Gene therapy using human FMRP isoforms driven by the human <i>FMR1</i> promoter rescues fragile X syndrome mouse deficits.

Jiang, Yiru; Han, Linkun; Meng, Jian; Wang, Zijie; Zhou, Yunqiang; Yuan, Huilong; Xu, Hui; Zhang, Xian; Zhao, Yingjun; Lu, Jinsheng; Xu, Huaxi; Zhang, Chen; Zhang, Yun-Wu

Gene therapy using human FMRP isoforms driven by the human FMR1 promoter rescues fragile X syndrome mouse deficits.

Jiang, Yiru; Han, Linkun; Meng, Jian; Wang, Zijie; Zhou, Yunqiang; Yuan, Huilong; Xu, Hui; Zhang, Xian; Zhao, Yingjun; Lu, Jinsheng; Xu, Huaxi; Zhang, Chen; Zhang, Yun-Wu.

Afiliación

Jiang Y; Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, and Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian 361102, China.
Han L; Emergency Department, Xiang'an Hospital of Xiamen University, Xiamen, Fujian 361102, China.
Meng J; Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, and Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian 361102, China.
Wang Z; Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, and Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian 361102, China.
Zhou Y; Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, and Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian 361102, China.
Yuan H; Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, and Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian 361102, China.
Xu H; Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, and Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian 361102, China.
Zhang X; Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, and Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian 361102, China.
Zhao Y; Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, and Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian 361102, China.
Lu J; Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, and Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian 361102, China.
Xu H; Emergency Department, Xiang'an Hospital of Xiamen University, Xiamen, Fujian 361102, China.
Zhang C; Geriatrics Department, Geriatric Hospital of Hainan, Haikou, Hainan 571100, China.
Zhang YW; Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, and Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian 361102, China.