A double-switch pHLIP system enables selective enrichment of circulating tumor microenvironment-derived extracellular vesicles.

Zong, Zhiyou; Liu, Xinzhuo; Ye, Zhuo; Liu, Dingbin

Zong, Zhiyou; Liu, Xinzhuo; Ye, Zhuo; Liu, Dingbin.

Afiliación

Zong Z; State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin 300071, China.
Liu X; State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin 300071, China.
Ye Z; State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin 300071, China.
Liu D; State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin 300071, China.

Proc Natl Acad Sci U S A ; 120(2): e2214912120, 2023 01 10.

Article en En | MEDLINE | ID: mdl-36595702

Asunto(s)

Vesículas Extracelulares; Neoplasias; Animales; Ratones; Biomarcadores de Tumor/genética; Microambiente Tumoral; Vesículas Extracelulares/genética; Biopsia Líquida

Palabras clave

computational design; conformational switch; extracellular vesicle; pHLIP; tumor microenvironment

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vesículas Extracelulares / Neoplasias Límite: Animals Idioma: En Año: 2023 Tipo del documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vesículas Extracelulares / Neoplasias Límite: Animals Idioma: En Año: 2023 Tipo del documento: Article