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FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms.
Stoklund Dittlau, Katarina; Terrie, Lisanne; Baatsen, Pieter; Kerstens, Axelle; De Swert, Lim; Janky, Rekin's; Corthout, Nikky; Masrori, Pegah; Van Damme, Philip; Hyttel, Poul; Meyer, Morten; Thorrez, Lieven; Freude, Kristine; Van Den Bosch, Ludo.
Afiliación
  • Stoklund Dittlau K; Department of Neurosciences, Experimental Neurology and Leuven Brain Institute, KU Leuven - University of Leuven, 3000, Leuven, Belgium.
  • Terrie L; VIB Center for Brain & Disease Research, Laboratory of Neurobiology, 3000, Leuven, Belgium.
  • Baatsen P; Department of Development and Regeneration, KU Leuven - University of Leuven, Campus Kulak, 8500, Kortrijk, Belgium.
  • Kerstens A; KU Leuven - University of Leuven, EM-Platform of the VIB Bio Imaging Core and VIB Center for Brain and Disease Research, Research Group Molecular Neurobiology, 3000, Leuven, Belgium.
  • De Swert L; KU Leuven - University of Leuven, VIB Bio Imaging Core; VIB Center for Brain & Disease Research, 3000, Leuven, Belgium.
  • Janky R; VIB Nucleomics Core, VIB, Herestraat 49, 3000, Leuven, Belgium.
  • Corthout N; VIB Nucleomics Core, VIB, Herestraat 49, 3000, Leuven, Belgium.
  • Masrori P; KU Leuven - University of Leuven, VIB Bio Imaging Core; VIB Center for Brain & Disease Research, 3000, Leuven, Belgium.
  • Van Damme P; Department of Neurosciences, Experimental Neurology and Leuven Brain Institute, KU Leuven - University of Leuven, 3000, Leuven, Belgium.
  • Hyttel P; VIB Center for Brain & Disease Research, Laboratory of Neurobiology, 3000, Leuven, Belgium.
  • Meyer M; Department of Neurology, University Hospitals Leuven, 3000, Leuven, Belgium.
  • Thorrez L; Department of Neurosciences, Experimental Neurology and Leuven Brain Institute, KU Leuven - University of Leuven, 3000, Leuven, Belgium.
  • Freude K; VIB Center for Brain & Disease Research, Laboratory of Neurobiology, 3000, Leuven, Belgium.
  • Van Den Bosch L; Department of Neurology, University Hospitals Leuven, 3000, Leuven, Belgium.
Mol Neurodegener ; 18(1): 5, 2023 01 18.
Article en En | MEDLINE | ID: mdl-36653804
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article