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RO6807936 as a novel positron emission tomography (PET) radiotracer for in vitro and in vivo visualization and quantification of beta-site amyloid precursor protein cleaving enzyme (BACE1) in the rodent and baboon brain.
Honer, Michael; Polara, Alessandra; Kuwabara, Hiroto; Jacobsen, Helmut; Pähler, Axel; Hartung, Thomas; Caruso, Antonello; Esterhazy, Daria; Stoffel, Markus; Dannals, Robert F; Wong, Dean F; Borroni, Edilio; Gobbi, Luca C.
Afiliación
  • Honer M; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Polara A; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Kuwabara H; Department of Radiology, Nuclear Medicine, PET Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Jacobsen H; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Pähler A; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Hartung T; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Caruso A; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Esterhazy D; Institute of Molecular Systems Biology, ETH, Zurich, Switzerland.
  • Stoffel M; Institute of Molecular Systems Biology, ETH, Zurich, Switzerland.
  • Dannals RF; Department of Radiology, Nuclear Medicine, PET Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Wong DF; Department of Radiology, Nuclear Medicine, PET Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Borroni E; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Gobbi LC; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
J Labelled Comp Radiopharm ; 66(9): 222-236, 2023 07.
Article en En | MEDLINE | ID: mdl-37095603
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Precursor de Proteína beta-Amiloide / Enfermedad de Alzheimer Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Precursor de Proteína beta-Amiloide / Enfermedad de Alzheimer Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article