Effect of Saccharolactone on CYP-mediated Metabolism of Xenobiotics.

Behera, Dayanidhi; Jain, Pankaj; Kurawattimath, Vishwanath; Gowda, Nagaraj

Behera, Dayanidhi; Jain, Pankaj; Kurawattimath, Vishwanath; Gowda, Nagaraj.

Afiliación

Behera D; Department of Drug Metabolism and Pharmacokinetics, Glenmark Pharmaceuticals Limited, Glenmark Research Centre, MIDC Mahape, Navi-Mumbai, Maharashtra, India.
Jain P; Department of Drug Metabolism and Pharmacokinetics, Glenmark Pharmaceuticals Limited, Glenmark Research Centre, MIDC Mahape, Navi-Mumbai, Maharashtra, India.
Kurawattimath V; Department of Drug Metabolism and Pharmacokinetics, Glenmark Pharmaceuticals Limited, Glenmark Research Centre, MIDC Mahape, Navi-Mumbai, Maharashtra, India.
Gowda N; Department of Drug Metabolism and Pharmacokinetics, Glenmark Pharmaceuticals Limited, Glenmark Research Centre, MIDC Mahape, Navi-Mumbai, Maharashtra, India.

Drug Metab Bioanal Lett ; 16(2): 121-132, 2023.

Article en En | MEDLINE | ID: mdl-37612873

Asunto(s)

Citocromo P-450 CYP1A2; Sistema Enzimático del Citocromo P-450; Humanos; Citocromo P-450 CYP1A2/metabolismo; Sistema Enzimático del Citocromo P-450/metabolismo; Citocromo P-450 CYP3A/metabolismo; Glucurónidos/metabolismo; Uridina Difosfato Ácido Glucurónico/metabolismo; Quinidina/farmacología; Xenobióticos/farmacología; NADP/metabolismo; Fenacetina/metabolismo; Microsomas Hepáticos; Isoformas de Proteínas/metabolismo; Peptaiboles/metabolismo

Palabras clave

CYP inhibition; Cytochrome P450 (CYP); UDP-glucuronosyltransferases (UGT); human liver microsomes; metabolism; saccharolactone; ß-glucuronidase

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Citocromo P-450 CYP1A2 / Sistema Enzimático del Citocromo P-450 Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article

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