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The H163A mutation unravels an oxidized conformation of the SARS-CoV-2 main protease.
Tran, Norman; Dasari, Sathish; Barwell, Sarah A E; McLeod, Matthew J; Kalyaanamoorthy, Subha; Holyoak, Todd; Ganesan, Aravindhan.
Afiliación
  • Tran N; Department of Biology, Faculty of Science, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada.
  • Dasari S; Department of Chemistry, Faculty of Science, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada.
  • Barwell SAE; Department of Biology, Faculty of Science, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada.
  • McLeod MJ; Physics Department, Cornell University, Ithaca, NY, 14853, USA.
  • Kalyaanamoorthy S; Department of Chemistry, Faculty of Science, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada.
  • Holyoak T; Department of Biology, Faculty of Science, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada. tholyoak@uwaterloo.ca.
  • Ganesan A; ArGan's Lab, School of Pharmacy, Faculty of Science, University of Waterloo, 10A Victoria Street South, Kitchener, ON, N2G 1C5, Canada. aravindhan.ganesan@uwaterloo.ca.
Nat Commun ; 14(1): 5625, 2023 09 12.
Article en En | MEDLINE | ID: mdl-37699927
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: COVID-19 Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: COVID-19 Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article