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Compartmentalizing damaged DNA: A double-edged sword.
Georgiades, Emily; Crosetto, Nicola; Bienko, Magda.
Afiliación
  • Georgiades E; Human Technopole, Viale Rita Levi-Montalcini 1, 20157 Milano, Italy.
  • Crosetto N; Human Technopole, Viale Rita Levi-Montalcini 1, 20157 Milano, Italy; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden; Science for Life Laboratory, Solna, Sweden. Electronic address: nicola.crosetto@fht.org.
  • Bienko M; Human Technopole, Viale Rita Levi-Montalcini 1, 20157 Milano, Italy; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden; Science for Life Laboratory, Solna, Sweden. Electronic address: magda.bienko@fht.org.
Mol Cell ; 84(1): 12-13, 2024 Jan 04.
Article en En | MEDLINE | ID: mdl-38181754
ABSTRACT
A recent publication in Nature by Arnould et al.1 describes a novel chromatin compartment, termed "damaged" or "D compartment," that facilitates the repair of DNA double-strand breaks but also increases the risk of potentially oncogenic translocation formation.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatina / Roturas del ADN de Doble Cadena Límite: Humans Idioma: En Año: 2024 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatina / Roturas del ADN de Doble Cadena Límite: Humans Idioma: En Año: 2024 Tipo del documento: Article