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Spectral tweezers: Single sample spectroscopy using optoelectronic tweezers.
Zaman, Mohammad Asif; Wu, Mo; Ren, Wei; Jensen, Michael A; Davis, Ronald W; Hesselink, Lambertus.
Afiliación
  • Zaman MA; Department of Electrical Engineering, Stanford University, Stanford, California 94305, USA.
  • Wu M; Department of Electrical Engineering, Stanford University, Stanford, California 94305, USA.
  • Ren W; Department of Electrical Engineering, Stanford University, Stanford, California 94305, USA.
  • Jensen MA; Department of Biochemistry, Stanford University, Stanford, California 94305, USA.
  • Davis RW; Department of Biochemistry, Stanford University, Stanford, California 94305, USA.
  • Hesselink L; Department of Electrical Engineering, Stanford University, Stanford, California 94305, USA.
Appl Phys Lett ; 124(7): 071104, 2024 Feb 12.
Article en En | MEDLINE | ID: mdl-38356894
ABSTRACT
A scheme that combines optoelectronic tweezers (OET) with spectroscopic analysis is presented. Referred to as spectral tweezers, the approach uses a single focused light beam that acts both as the trapping beam for OET and the probe beam for spectroscopy. Having simultaneous manipulation and spectral characterization ability, the method is used to isolate single micro-samples from clusters and perform spectral measurements. Experimental results show that a characteristic spectral signature can be obtained for a given sample. The proposed approach can be easily integrated into the optical setups used for conventional OETs with only a few additional optical components, making it a convenient tool for bio-analytical applications.