Glutamicibacter nicotianae AT6: A new strain for the efficient biodegradation of tilmicosin.
J Environ Sci (China)
; 142: 182-192, 2024 Aug.
Article
en En
| MEDLINE
| ID: mdl-38527883
ABSTRACT
The degradation of tilmicosin (TLM), a semi-synthetic 16-membered macrolide antibiotic, has been receiving increasing attention. Conventionally, there are three tilmicosin degradation methods, and among them microbial degradation is considered the best due to its high efficiency, eco-friendliness, and low cost. Coincidently, we found a new strain, Glutamicibacter nicotianae sp. AT6, capable of degrading high-concentration TLM at 100 mg/L with a 97% removal efficiency. The role of tryptone was as well investigated, and the results revealed that the loading of tryptone had a significant influence on TLM removals. The toxicity assessment indicated that strain AT6 could efficiently convert TLM into less-toxic substances. Based on the identified intermediates, the degradation of TLM by AT6 processing through two distinct pathways was then proposed.
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1
Banco de datos:
MEDLINE
Asunto principal:
Tilosina
/
Aguas Residuales
/
Micrococcaceae
Idioma:
En
Año:
2024
Tipo del documento:
Article