Necrotizing enterocolitis in premature infants at different gestation ages.
Wiad Lek
; 77(3): 409-416, 2024.
Article
en En
| MEDLINE
| ID: mdl-38691780
ABSTRACT
OBJECTIVE:
Aim:
To compare X-ray signs in different gestational and body weight groups of patients with NEC. PATIENTS ANDMETHODS:
Materials andMethods:
We conducted a retrospective study, enrolling 52 preterm newborns with symptoms of NEC regardless of onset time, who underwent treatment at Neonatal Intensive Care Units in Municipal Non-commercial enterprise "City Children Hospital â2", Odesa. The patients were split into 3 clinical groups very preterm newborns (VPN), moderately preterm newborns (MPN), and moderately preterm newborns with intrauterine growth restriction (MPN+IUGR).RESULTS:
Results:
In the VPN group NEC was diagnosed at stage II (58,82±12,30) % and III (41,18±12,30) % by Bell MJ, Ñ>0,05. In the group MPN+IUGR, NEC stage II (33,33±14,21) % and stage III (66,66 ±14,21) %, Ñ>0,05, were equally observed. In the MPN group, NEC was diagnosed at stage I (41,67±10,28) % and II (58,33±10,28) %, Ñ>0,05, without prevalence of any. Also only localized forms were observed. In VPN, we observed localized forms in most cases, while diffuse forms were diagnosed in (11,76±8,05) % cases, Ñ<0,05. In the MPN+IUGR group, we found diffuse form of the NEC in half of the cases - (50,00±15,08) %. In the VPN and MPN+IUGR groups, NEC developed at 13,23±0,39 and 14,33±1,19 days, respectively. However, in MPN without IUGR, NEC developed at 17,75±0,55 days, significantly later than in the MPN+IUGR group, Ñ<0,05.CONCLUSION:
Conclusions:
We have described distinct features of NEC in MPN with IUGR. Compared to MPN without IUGR, NEC had more severe course and earlier manifestation in such neonates.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Recien Nacido Prematuro
/
Edad Gestacional
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Enterocolitis Necrotizante
Límite:
Female
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Humans
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Male
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Newborn
Idioma:
En
Año:
2024
Tipo del documento:
Article