Towards personalized medicine for the treatment of equine asthma.
Vet J
; 305: 106125, 2024 Jun.
Article
en En
| MEDLINE
| ID: mdl-38704018
ABSTRACT
Although horses with asthma share similar clinical signs, the heterogeneity of the disease in terms of severity, triggering factors, inflammatory profile, and pathological features has hindered our ability to define biologically distinct subgroups. The recognition of phenotypes and endotypes could enable the development of precision medicine, including personalized, targeted therapy, to benefit affected horses. While in its infancy in horses, this review outlines the phenotypes of equine asthma and discusses how knowledge gained from targeted therapy in human medicine can be applied to evaluate the potential opportunities for personalized medicine in equine asthma and to suggest avenues for research to advance this emerging field.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Asma
/
Medicina de Precisión
/
Enfermedades de los Caballos
Límite:
Animals
Idioma:
En
Año:
2024
Tipo del documento:
Article