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Zhongguo Dang Dai Er Ke Za Zhi
; 26(6): 611-618, 2024 Jun 15.
Article
en Zh
| MEDLINE
| ID: mdl-38926378
ABSTRACT
OBJECTIVES:
To investigate the risk factors for bronchopulmonary dysplasia (BPD) in twin preterm infants with a gestational age of <34 weeks, and to provide a basis for early identification of BPD in twin preterm infants in clinical practice.METHODS:
A retrospective analysis was performed for the twin preterm infants with a gestational age of <34 weeks who were admitted to 22 hospitals nationwide from January 2018 to December 2020. According to their conditions, they were divided into group A (both twins had BPD), group B (only one twin had BPD), and group C (neither twin had BPD). The risk factors for BPD in twin preterm infants were analyzed. Further analysis was conducted on group B to investigate the postnatal risk factors for BPD within twins.RESULTS:
A total of 904 pairs of twins with a gestational age of <34 weeks were included in this study. The multivariate logistic regression analysis showed that compared with group C, birth weight discordance of >25% between the twins was an independent risk factor for BPD in one of the twins (OR=3.370, 95%CI 1.500-7.568, P<0.05), and high gestational age at birth was a protective factor against BPD (P<0.05). The conditional logistic regression analysis of group B showed that small-for-gestational-age (SGA) birth was an independent risk factor for BPD in individual twins (OR=5.017, 95%CI 1.040-24.190, P<0.05).CONCLUSIONS:
The development of BPD in twin preterm infants is associated with gestational age, birth weight discordance between the twins, and SGA birth.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Gemelos
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Displasia Broncopulmonar
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Recien Nacido Prematuro
Límite:
Female
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Humans
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Male
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Newborn
Idioma:
Zh
Año:
2024
Tipo del documento:
Article