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Radiology and multi-scale data integration for precision oncology.
Paverd, Hania; Zormpas-Petridis, Konstantinos; Clayton, Hannah; Burge, Sarah; Crispin-Ortuzar, Mireia.
Afiliación
  • Paverd H; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Zormpas-Petridis K; Department of Oncology, University of Cambridge, Cambridge, UK.
  • Clayton H; Cancer Research UK Cambridge Centre, University of Cambridge, Cambridge, UK.
  • Burge S; Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
  • Crispin-Ortuzar M; Department of Oncology, University of Cambridge, Cambridge, UK.
NPJ Precis Oncol ; 8(1): 158, 2024 Jul 26.
Article en En | MEDLINE | ID: mdl-39060351
ABSTRACT
In this Perspective paper we explore the potential of integrating radiological imaging with other data types, a critical yet underdeveloped area in comparison to the fusion of other multi-omic data. Radiological images provide a comprehensive, three-dimensional view of cancer, capturing features that would be missed by biopsies or other data modalities. This paper explores the complexities and challenges of incorporating medical imaging into data integration models, in the context of precision oncology. We present the different categories of imaging-omics integration and discuss recent progress, highlighting the opportunities that arise from bringing together spatial data on different scales.