Glycoprotein-like large glucagon immunoreactive species in extracts of the fetal bovine pancreas.
Diabetes
; 31(11): 1002-5, 1982 Nov.
Article
en En
| MEDLINE
| ID: mdl-6897390
ABSTRACT
Large glucagon immunoreactive substances, extracted from the fetal bovine pancreas and separated by gel filtration in the presence of 6 M guanidinium-hydrochloride, were submitted to lectin-sepharose affinity column chromatograph. Gel-filtered peak I (approximately 45 K delta) and peak II (approximately 10 K delta) interacted biospecifically with concanavalin-A- and wheat-germ-lectin-sepharoses, suggesting glycoproteins as possible constituents of large glucagon immunoreactive substances in extracts of the fetal bovine pancreas. The glucagon-like immunochemical identity of the lectin-sepharose-bound substances was further substantiated by binding to antiglucagon antibodies-sepharose and by characteristic proportional dilutions in the glucagon radioimmunoassay.
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Banco de datos:
MEDLINE
Asunto principal:
Páncreas
/
Péptidos
/
Glucagón
/
Glicoproteínas
Límite:
Animals
Idioma:
En
Año:
1982
Tipo del documento:
Article