Brodimoprim, a new bacterial dihydrofolate reductase inhibitor: a minireview.
J Chemother
; 7(3): 221-3, 1995 Jun.
Article
en En
| MEDLINE
| ID: mdl-7562018
ABSTRACT
This brief review article synthesizes the principal literature regarding the clinical status of co-trimoxazole compared to monotherapy with one of the two diaminopyrimidines available commercially trimethoprim or brodimoprim. Both these inhibitors of bacterial dihydrofolate reductase compare favorably to co-trimoxazole as antimicrobial chemotherapy. Brodimoprim is characterized by its advantageous pharmacokinetics in comparison to both co-trimoxazole and trimethoprim.
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Banco de datos:
MEDLINE
Asunto principal:
Tetrahidrofolato Deshidrogenasa
/
Trimetoprim
/
Antagonistas del Ácido Fólico
Límite:
Humans
Idioma:
En
Año:
1995
Tipo del documento:
Article