Contribution of cohort studies in understanding HIV pathogenesis: introduction of the GRIV cohort and preliminary results.
Biomed Pharmacother
; 50(10): 480-7, 1996.
Article
en En
| MEDLINE
| ID: mdl-9091061
ABSTRACT
In the present paper we review studies performed on HIV-infected patients cohorts in order to understand AIDS disease development. The interplay between diverse factors such as the HIV envelope proteins, cellular co-receptors, the immune response with chemokines and cytokines production define the viral tropism, cytopathicity and progression of HIV disease. We present the trends of the research particularly in the domain concerning host genetics. In this context, we describe the GRIV cohort of fast and slow/non-progressors, and its use for understanding basic features of the yet unknown HIV pathogenesis mechanisms.
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Banco de datos:
MEDLINE
Asunto principal:
Infecciones por VIH
/
Síndrome de Inmunodeficiencia Adquirida
/
VIH
/
Receptores de Quimiocina
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Año:
1996
Tipo del documento:
Article