Effect of sucralfate on gastric intramucosal pH in critically ill patients.
Intensive Care Med
; 23(7): 738-42, 1997 Jul.
Article
en En
| MEDLINE
| ID: mdl-9290986
ABSTRACT
OBJECTIVE:
To determine whether sucralfate administration affects the tonometric measurement of gastric intramucosal pH (pHi).DESIGN:
Non-randomized observational study.SETTING:
General intensive care unit of a teaching hospital. PATIENTS Twenty critically ill, mechanically ventilated, consecutively admitted patients requiring an arterial catheter and nasogastric tube.INTERVENTIONS:
Tonometer placement and sucralfate administration. MEASUREMENTS AND MAINRESULTS:
We simultaneously determined tonometer saline PCO2 (PCO2i), arterial blood gases, pH of gastric juice and pHi. These parameters were evaluated immediately before sucralfate administration, and 2 h and 4 h after. We did not detect any change in either PCO2i or pHi after sucralfate administration (PCO2i basal 6.4 +/- 1.7, 2 h 6.3 +/- 1.7, 4 h 6.3 +/- 1.7; pHi basal 7.35 +/- 0.13, 2 h 7.36 +/- 0.12, 4 h 7.36 +/- 0.12).CONCLUSIONS:
Sucralfate does not affect the tonometric measurement of PCO2i and pHi.
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Banco de datos:
MEDLINE
Asunto principal:
Sucralfato
/
Enfermedad Crítica
/
Mucosa Gástrica
/
Antiulcerosos
Tipo de estudio:
Clinical_trials
/
Observational_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Año:
1997
Tipo del documento:
Article