The use of polydimethylsiloxane in the treatment of incontinence after radical prostatectomy.
Br J Urol
; 80(6): 923-6, 1997 Dec.
Article
en En
| MEDLINE
| ID: mdl-9439411
ABSTRACT
OBJECTIVE:
To report the results of transurethral submucosal injection therapy of polydimethylsiloxane (PDS) to treat incontinence after radical prostatectomy (RP). PATIENTS ANDMETHODS:
Since 1993, about 80 retropubic RPs have been carried out at our institution each year. Severe post-operative incontinence occurred in six patients, with a mean duration of incontinence after RP of 28 months. The pre-operative evaluation consisted of cysto-urethroscopy and urodynamics. Because we have no experience with artificial sphincter implantation, transurethral injection therapy was used to treat the post-operative incontinence, using PDS (vulcanized silicone rubber particles). This material has a mean particle size of 188 microns, providing stability of the material at the injection site. The six patients with severe post-operative incontinence were treated using injection therapy with PDS.RESULTS:
After a mean follow up of 15.5 months, five patients, who suffered from day and night incontinence and required at least five pads per day, were dry after injection therapy. One patient improved significantly but still required two pads during the day, but was continent during the night; three patients required a second injection. A mean of 7.5 mL of PDS was used per patient and the side-effects of therapy (dysuria and urinary retention) were minimal.CONCLUSION:
Because PDS has excellent biocompatibility, few side-effects or complications, transurethral injection therapy using silicone particles is a justifiable procedure for treating incontinence after RP.
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Banco de datos:
MEDLINE
Asunto principal:
Prostatectomía
/
Siliconas
/
Incontinencia Urinaria
/
Agentes Mojantes
/
Dimetilpolisiloxanos
Tipo de estudio:
Etiology_studies
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Año:
1997
Tipo del documento:
Article