ABSTRACT
Perioperative chemotherapy (CT) and chemoradiotherapy are widely used for advanced esophageal cancer. We evaluated the chemosensitivity of patients displaying recurrent esophageal cancer after esophagectomy with perioperative CT. From the database at National Cancer Center Hospital in Tokyo, we extracted recurrent esophageal cancer cases after perioperative CT and evaluated the effectiveness of the first CT against the recurrent disease according to the duration between termination of the original perioperative CT and recurrence with treatment-free intervals (TFIs) Subject(s)
Antineoplastic Agents/therapeutic use
, Carcinoma, Squamous Cell/drug therapy
, Carcinoma, Squamous Cell/secondary
, Esophageal Neoplasms/drug therapy
, Esophageal Neoplasms/surgery
, Aged
, Carcinoma, Squamous Cell/surgery
, Chemotherapy, Adjuvant
, Cisplatin/therapeutic use
, Cohort Studies
, Databases, Factual
, Disease-Free Survival
, Esophageal Neoplasms/pathology
, Esophagectomy
, Female
, Fluorouracil/therapeutic use
, Humans
, Male
, Middle Aged
, Retrospective Studies