ABSTRACT
Based on the systematic summary of the results of the fourth general survey of traditional Chinese medicine resources, the cultivation of large varieties of Chinese material medica and the latest research on health industrial development, the novel concepts and scientific connotations of generalized science of Chinese material medica are put forward, and the basic ideas and methods of a new Chinese medicine academic system, the cultivation system of large varieties of Chinese medicinal materials and the application system of the large health industry are constructed. This kind of generalized science of Chinese material medica, rooted in the traditional Chinese culture and the theory of "preventive treatment of disease", can avoid the narrow prospect induced by the increasing specialization and refinement of knowledge of science of Chinese material medica. It will play an important role in the modernization, industrialization, internationalization of traditional Chinese medicine.
Subject(s)
Humans , Drug Industry , Materia Medica , Therapeutic Uses , Medicine, Chinese Traditional , ResearchABSTRACT
<p><b>OBJECTIVE</b>To establish scientific and efficient quality control standard of Rhizoma et Radix Notopterygii through two quantitative parameters.</p><p><b>METHOD</b>The contents of isoimperatorin and volatile oils in 29 commercial samples from 22 localities of Rhizoma et Radix Notopterygii were determined by HPLC and the method in the pharmacopoeia respectively. The data were statistically analyzed.</p><p><b>RESULT</b>Only 3 of 29 samples met the required standard in the Chinese Pharmacopoeia (2005 edition), 87% of samples newly produced in 2005 not met the standard. Statistics showed that the contents of volatile oils and isoimperatorin should reach 1.63% and 0.17% respectively when the samples meet requirement of criterion with more than 80% probability. The contents of volatile oil and isoimperatorin were not significantly different (P < 0.05) in the samples of 2005 and 2003, while the contents of isoimperatorin were significantly different between Notopterygium incisum and N. forbesii samples.</p><p><b>CONCLUSION</b>Since the criterion of volatile oils in the Chinese Pharmacopoeia (2005 version) for Rhizoma et Radix Notopterygii is too high to satisfy for most Rhizoma et Radix Notopterygii samples, it is suggested to reduce it to 1.6% (mL x g(-1)). The content of isoimperatorin is proposed to add to the quality standard of Rhizoma et Radix Notopterygii as above 0.2% (mg x g(-1)).</p>
Subject(s)
Apiaceae , Chemistry , Classification , China , Chromatography, High Pressure Liquid , Furocoumarins , Oils, Volatile , Chemistry , Plant Roots , Chemistry , Plants, Medicinal , Chemistry , Reproducibility of Results , Rhizome , ChemistryABSTRACT
<p><b>OBJECTIVE</b>To explore the preparation technology of beta-cyclodextrin inclusion compound for chuanxiong volatile oil.</p><p><b>METHOD</b>Orthogonal test was used to evaluate the influence of the 4 factors, including the proportion of volatile oil to beta-cyclodextrin, the mode of mixing, inclusion temperature and mixing time.</p><p><b>RESULT</b>The best inclusion condition is the proportion of volatile oil to beta-cyclodextrin 1:9, the mode of mixing grinding, inclusion temperature 60 degrees C and inclusion time 90 min.</p><p><b>CONCLUSION</b>The best inclusion technology of chuanxiong volatile oil is confirmed.</p>