ABSTRACT
OBJECTIVE: The internet plays an important role in the search for health-specific information. So far, only a few studies exist on the user-friendliness of medical websites. This study thus examines the web presence of otorhinolaryngologists in private practice in Bavaria. METHODS: All otorhinolaryngologists registered with statutory health insurance in Bavaria were evaluated using a standardized checklist. IBM SPSS version 25 (IBM Corp., Armonk, NY, USA) statistical software was used for the analysis. RESULTS: Among all otorhinolaryngologists (nâ¯= 448), 73.0% (nâ¯= 327) had their own functioning website. Only a minority of websites (1.5%) had options to adjust the font size. Regarding functional possibilities of the websites, 18.3% of the physicians offered an online appointment calendar and 3.7% the possibility of feedback. A liability disclaimer was missing on 21.6% of all websites. CONCLUSION: The results exhibit an inadequate use of criteria catalogues for web presence. A patient-oriented website configuration could help to improve customer acquisition and satisfaction, which is particularly relevant for cities with a high density of physicians.
Subject(s)
Internet , Otolaryngology , Patient Education as Topic , Private Practice , Communication , Humans , National Health Programs , SoftwareABSTRACT
Allergic contact dermatitis (ACD) may account for at least 20% of all childhood dermatitis. Clinically, its morphology is identical to other forms of dermatitis in acute, subacute and chronic forms. A persistent or unusual and localized pattern is often the key to diagnosis. Treatment has centered around the use of corticosteroids, with the adjunct of antihistamines, wet dressings, and emollients for alleviation of symptoms. The newer topical immunosuppressives, tacrolimus and pimecrolimus, may also hold promise as alternative therapies, although they have not been well-studied in this regard. Allergen identification, sometimes through patch testing and allergen avoidance are the keys to preventing recurrences of this disease.
Subject(s)
Adrenal Cortex Hormones/therapeutic use , Dermatitis, Allergic Contact/drug therapy , Animals , Child , Dermatitis, Allergic Contact/immunology , Histamine H1 Antagonists/therapeutic use , Humans , Immunosuppressive Agents/therapeutic useABSTRACT
An analytical assay is presented for the determination of the enantiomeric composition of galanthamine and related synthetic and natural compounds. (-)-Galanthamine is isolated from Galanthus nivalis and is used in this optical pure form in the therapy of Alzheimer's disease. Recent efforts for a total synthesis of unichiral (-)-galanthamine is connected with the need for a fast and reliable assay for the determination of the optical purity of the end product, as well as for optimizing and controlling the final steps in total synthesis particularly the asymmetric transformation of narwedine. In this paper the enantiomeric resolution of these compounds is reported employing a capillary electrophoretic system with beta-cyclodextrin derived chiral selectors. With the proposed system a number of galanthamine and narwedine derived analogous compounds could be separated, including 1-bromo- and N-alkyl-substituted compounds.
Subject(s)
Alzheimer Disease/drug therapy , Electrophoresis, Capillary/methods , Galantamine/isolation & purification , Nootropic Agents/isolation & purification , Galantamine/chemistry , Galantamine/therapeutic use , Galanthus , Humans , Nootropic Agents/chemistry , Nootropic Agents/therapeutic use , Reproducibility of Results , Sensitivity and Specificity , StereoisomerismABSTRACT
La coca es una de las plantas de cultivo más antiguo de los pueblos de Sur américa, constituyendo uno de los más importantes de Bolivia. Una parte de la producción es consumida tradicionalmente por los campesinos (principalmente bajo la forma del acullicu) alrededor de 10.000 toneladas sobre las 60.000 a 80.000 toneladas producidas anualmente en el país (Carter y Mamani, 1986). Las preguntas que habitualmente se hace la población boliviana sobre las cualidades de la hoja de coca son las siguientes: ¿Existen distintas variedades de coca cultivadas en Bolivia? ¿La hoja de coca en su estado natural, tiene o no cocaína? ¿Cuántos compuestos diferentes están presentes en la hoja de coca? ¿Cuál es el compuesto responsable de sus propiedades medicinales? (AU)