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1.
Science ; 382(6666): 73-75, 2023 10 06.
Article in English | MEDLINE | ID: mdl-37797035

ABSTRACT

Human footprints at White Sands National Park, New Mexico, USA, reportedly date to between ~23,000 and 21,000 years ago according to radiocarbon dating of seeds from the aquatic plant Ruppia cirrhosa. These ages remain controversial because of potential old carbon reservoir effects that could compromise their accuracy. We present new calibrated 14C ages of terrestrial pollen collected from the same stratigraphic horizons as those of the Ruppia seeds, along with optically stimulated luminescence ages of sediments from within the human footprint-bearing sequence, to evaluate the veracity of the seed ages. The results show that the chronologic framework originally established for the White Sands footprints is robust and reaffirm that humans were present in North America during the Last Glacial Maximum.


Subject(s)
Biological Evolution , Hominidae , Animals , Humans , Luminescence , North America , Radiometric Dating/methods , New Mexico , Parks, Recreational , Pollen , Alismatales , Carbon Radioisotopes , Seeds
2.
J Tissue Viability ; 31(1): 173-179, 2022 Feb.
Article in English | MEDLINE | ID: mdl-34774393

ABSTRACT

As the skin is the main protective organ of the body, it is exposed to wounds or injuries which carry out a healing process during a period of approximately 15 days depending on the severity of the injury. In the present research, the development of chitosan-based hydrogels loaded with silver nanoparticles and calendula extract (Ch-AgNPs-Ce) was proposed. This can be used to fulfill the hemostatic, anti-infective, antibacterial, healing and anti-inflammatory functions through controlled release of the nanoparticles and calendula extract in substitution of commonly used drugs. The physical properties of the silver nanoparticles were analyzed by UV-visible spectroscopy, scanning and transmission electron microscopy, showing a size between 50 and 100 nm. The antibacterial properties were evaluated by the agar well diffusion method. Antimicrobial testing of the hydrogels showed that the inclusion of silver nanoparticles provides concentration-dependent antibacterial behavior against E. coli and S. aureus. The healing properties of the system were tested in two diabetic patients to whom said hydrogels were placed, obtaining a positive curative result after a few weeks. Therefore, it can be concluded that Ch-AgNPs-Ce hydrogels can achieve healing in chronic or exposed wounds after a period of time which can be used in alternative treatments in patients with poor healing capacity.


Subject(s)
Chitosan , Metal Nanoparticles , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/therapeutic use , Calendula , Chitosan/pharmacology , Delayed-Action Preparations , Escherichia coli , Humans , Hydrogels/pharmacology , Plant Extracts , Silver/pharmacology , Staphylococcus aureus , Wound Healing
3.
Rev. med. vet. (Bogota) ; (7): 83-93, mayo 2004. tab
Article in Spanish | LILACS | ID: lil-560465

ABSTRACT

En este estudio se suplementaron cerdas con aminoácidos y vitaminas durante el último tercio de gestación y la lactancia para evaluar la respuesta sobre algunos parámetros reproductivos de la cerda. El estudio se realizó en una granja porcina localizada en el municipio de San Antonio del Tequendama con cerdas de la línea Dekalb. Se trabajó con dos grupos de animales cada uno compuesto por 30 cerdas seleccionadas y tratadas de la siguiente forma: Grupo experimental 1, al día 85 de gestación se le administró 3ml de Vitacalier vía intramuscular, al mismo tiempo que se le comenzó la administración de 5 gr diarios de Promocalier en el concentrado hasta el destete y 5ml de Robavit vía intramuscular al comienzo del parto; el grupo control 2, no recibió tratamiento. Se evaluaron los siguientes parámetros: a. Peso de la camada al nacimiento, b. Peso de la camada al destete, c. Nacidos muertos, d. Ganancia de pesos, e. Días de lactancia. En lo que respecta a los parámetros a, b, c, y d, no hubo diferencias significativas entre grupos; los resultados fueron: a. Con un peso de 1.52 y 1.40 Kg para los grupos 1 y 2 respectivamente; el parámetro b. Con valores de 5.97 Kg (grupo1) y (6.27 Kg (grupo2); el parámetro c. Nacidos muertos 1.83 lechones (grupo1) y 2.17 lechones (grupo 2); en lo que respecta al parámetro d. Los resultados obtenidos fueron de 0.2441 Kg (grupo 1) y 0.2399 Kg (grupo 2); a diferencia de los parámetros anteriores el parámetro e. reveló una diferencia significativa (p<0.05) entre grupos (18.6 días grupo 1 y 20.2 días grupo 2.) A diferencia del análisis estadístico el estudio representa ganancias económicas para el productor por el aumento de los kilogramos producidos y disminución de los días de lactancia, siendo rentable el uso de suplementos en granjas con estas características...


Subject(s)
Animals , Avitaminosis , Amino Acid Chloromethyl Ketones , Pregnancy , Stillbirth , Birth Weight
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