ABSTRACT
Aconitum kusnezoffi leaves and their extracts were analyzed and evaluated by fourier transform infrared spectroscopy, second derivative spectra, and two dimensional correlation infrared spectroscopy in this research. There was characteristic IR absorption peaks of polyose (767 cm(-1)) in the Aconitum kusnezoffii leaves. The IR spectra of the aether extract were similar with the ethanol extract of Aconitum kusnezoffi leaves. The strong absorption peaks of carbonyl (1 715 cm(-1)) and saturated alkyl groups (2 921, 2 851 cm(-1)) could be detected. Some fatty acids were also detected in the water extract. Infrared spectroscopy, combined with two dimensional correlation infrared spectroscopy, can provide much structural information for herbs, which will benefit the quality control, components tracing and identification of extraction process of herbs roundly and qualitatively.
Subject(s)
Aconitum , Chemistry , Plant Extracts , Chemistry , Plant Leaves , Chemistry , Spectroscopy, Fourier Transform InfraredABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy and feasibility of the Chinese drugs for supplementing Qi and activating blood circulation in preventing DVT after big operations in orthopaedics and traumatology and observe the change of D-dimer before and after treatment.</p><p><b>METHOD</b>Seventy patients ranging in age from 39 to 94 years who were treated by big operations in orthopaedics and traumatology were divided into two groups randomly. Traditional Chinese medinine (TCM) group (group A) and western medicine group (group B). On the 2rd day after operation d-dimer was tested from both groups and the patients in group A were given one dose of TCM every day and the patients in group B were subcutaneously injected low-molecular-weight heparins calcium (LMWH). On the 8th after operation d-dimer was tested again from both groups. The parameters, such as the incidence of DVT and pulmonary thromboembolism, bleeding condition, were evaluated respectively.</p><p><b>RESULT</b>The D-dimer decreased in group A and had significant difference (P < 0.05), group B had no significant difference, there was also no significant difference between two groups. DVT was found in 1 patient in group B (1/35). Petechiae were found in 10 patients in group A (10/35) and in 26 patients in group A (26/35), which had significant difference (P < 0.05).</p><p><b>CONCLUSION</b>Both the Chinese drugs and anti-coagulation drug can prevent the incidence of DVT effectively, and Chinese herbs are feasible in the prevention of DVT.</p>