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Therapeutic Methods and Therapies TCIM
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1.
Ear Nose Throat J ; 91(11): 488-92, 2012 Nov.
Article in English | MEDLINE | ID: mdl-23288796

ABSTRACT

We report our assessment of the effectiveness of bipolar radiofrequency-induced interstitial thermoablation (BRIT) for the treatment of certain oral cavity vascular malformations in 5 children. Two of these patients had lymphangiomatous macroglossia (LM), 1 had lymphangioma circumscriptum (LC), and 2 had a venous malformation (VM). Each patient underwent BRIT at least twice; treatment was delivered at 4- to 8-week intervals according to each patient's circumstances. The 2 patients with LM required three treatment sessions; although their tongue volume decreased after each session, both still required a partial glossectomy to achieve a satisfactory reduction in volume. The patient with LC underwent two BRIT treatments, which reduced the size of the lesion by half; the remainder was excised. The 2 patients with a VM (1 buccal and 1 lingual) responded well to BRIT, and their malformations almost completely disappeared. Our early results with BRIT suggest that it is an effective treatment for oral cavity vascular malformations-more so for patients with venous rather than lymphangiomatous lesions.


Subject(s)
Catheter Ablation/methods , Hyperthermia, Induced/methods , Lymphangioma/therapy , Tongue Neoplasms/therapy , Vascular Malformations/therapy , Adolescent , Child , Child, Preschool , Female , Humans , Macroglossia/therapy , Male , Tongue Diseases/therapy , Treatment Outcome
2.
Otol Neurotol ; 27(4): 478-83, 2006 Jun.
Article in English | MEDLINE | ID: mdl-16791038

ABSTRACT

OBJECTIVE: The functional evaluation of the effect of the hyperbaric oxygen therapy (HBOT) onset time on cochlea by using distortion product otoacoustic emission. STUDY DESIGN: Animal study. METHODS: Twenty-four Wistar albino rats were divided into six groups and their right ears were directly exposed to a 110-dB sound pressure level (1-12 kHz) white noise for 25 minutes. The first group was considered the control group. HBOT was started at 1 hour postexposure for the second group, at 2 hours postexposure for the third group, at 6 hours postexposure for the fourth group, at 24 hours postexposure for the fifth group, and at 48 hours postexposure for the sixth group. Signal-to-noise ratios (SNRs) were recorded before the noise exposure; immediately after the noise exposure; and on the 3rd, 7th, and 10th day of postexposure. RESULTS: SNRs at 6 to 8 kHz were significantly decreased after the acoustic trauma. The evaluation on the third day of postexposure showed that recovery begun in all groups except the group in which the HBOT was started at 1 hour postexposure. SNRs in the control group and HBOT groups were back to the preexposure levels at 10 days postexposure, except the 1- and 2-hour postexposure groups. However, in the group in which the HBOT was started at 1 hour postexposure, distortion product otoacoustic emissions were lost except at 4 kHz. The recovery of the SNRs in hyperbaric oxygen administration at 2 hours postexposure almost completed on the 10th day after noise exposure. CONCLUSION: Immediate HBOT in acoustic trauma treatment is not necessary; on the contrary, it has an adverse effect.


Subject(s)
Hearing Loss, Noise-Induced/therapy , Hyperbaric Oxygenation/adverse effects , Noise/adverse effects , Otoacoustic Emissions, Spontaneous/physiology , Acute Disease , Animals , Hearing Loss, Noise-Induced/physiopathology , Hyperbaric Oxygenation/methods , Rats , Rats, Wistar , Time Factors , Treatment Failure
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