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Therapeutic Methods and Therapies TCIM
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Acta Pharmaceutica Sinica ; (12): 1231-1236, 2011.
Article in Chinese | WPRIM | ID: wpr-233006

ABSTRACT

In order to clarify the chemical constituents in Qiliqiangxin capsule, a rapid ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry (UPLC-Q-TOF/MS(E)) method was established. Forty peaks were identified on line using this method. The herbal sources of these peaks were assigned. The results implied that triterpenoid saponins, flavonoid glycosides, C21-steroids and phenolic acids were included in the main components of Qiliqiangxin capsule. The method is simple and rapid for elucidation of the constituents of Qiliqiangxin capsule and the results are useful for the quality control of Qiliqiangxin capsule.


Subject(s)
Capsules , Chromatography, High Pressure Liquid , Drugs, Chinese Herbal , Chemistry , Flavones , Ginsenosides , Glycosides , Hydroxybenzoates , Plants, Medicinal , Chemistry , Quality Control , Saponins , Spectrometry, Mass, Electrospray Ionization , Steroids , Tandem Mass Spectrometry , Triterpenes
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