ABSTRACT
The study presents the findings of longitudinal observations of the changes in the parameters of simple auditory-motor response in children-users of mobile communication. The obtained results indicate the multivariability of possible effects of radiation from mobile phones on the auditory system of children.
Subject(s)
Audiometry/methods , Auditory Perceptual Disorders/etiology , Cell Phone/standards , Hearing/radiation effects , Psychomotor Performance/radiation effects , Radio Waves/adverse effects , Acoustic Stimulation , Age Factors , Auditory Perceptual Disorders/diagnosis , Auditory Perceptual Disorders/epidemiology , Case-Control Studies , Child , Child, Preschool , Dose-Response Relationship, Radiation , Humans , Longitudinal Studies , Psychomotor Performance/physiology , Reaction Time/physiology , Reaction Time/radiation effects , Task Performance and Analysis , Time FactorsABSTRACT
There are cases of development of a convulsive syndrome at influence of electromagnetic field (EMF) in physiotherapy practice, and in conditions of a professional work. There is a point of view that EMF can render medical effect at treatment of a epilepsy syndrome. Some publications specify on develop of epilepsy convulsions in experiment at EMF of various frequencies exposure. Four conditions which can promote development of convulsions at EMF exposure are considered.
Subject(s)
Brain/radiation effects , Electromagnetic Fields/adverse effects , Magnetic Field Therapy/adverse effects , Seizures/etiology , Animals , Brain/physiopathology , Cell Phone , Humans , Occupational Exposure , Seizures/physiopathology , SyndromeABSTRACT
The experiments with dogs exposed to 100 Gy of accelerated electrons demonstrated a significant role of prostaglandins in the origin of early post-radiation dyspepsia. Their significance for genesis of post-radiation dyspeptic disturbance caused by exposure to superhigh doses becomes clear-cut when a combination of an antiemetic and inhibitors of prostaglandin biosynthesis is used. A study of the effect of dexamethasone, a blocker of arachidonic acid release, and of voltaren, an inhibitor of prostaglandin formation from cyclic endoperoxide, suggests that it would be appropriate to prevent radiation vomiting and diarrhea by inhibiting both of the above stages in prostaglandin biosynthesis.
Subject(s)
Dyspepsia/etiology , Electrons , Prostaglandins/radiation effects , Radiation Injuries, Experimental/complications , Acute Disease , Animals , Antiemetics/therapeutic use , Benzamides/therapeutic use , Dexamethasone/therapeutic use , Diclofenac/therapeutic use , Disease Models, Animal , Dogs , Dose-Response Relationship, Radiation , Drug Evaluation, Preclinical , Drug Therapy, Combination , Dyspepsia/drug therapy , Female , Male , Particle Accelerators , Prostaglandin Antagonists/therapeutic use , Radiation Injuries, Experimental/drug therapy , Random Allocation , Time FactorsABSTRACT
The experiments with M. fasciculata monkeys exposed to 137Cs gamma-radiation with a dose of 6.9 Gy showed that Latranum, a blocker of serotonin 5-HT3 receptors, is a more efficient antiemetic than Dimetphramidum, a D2 dophamin lytic. This is suggested by fewer animals with emetic reaction of by less severe vomiting in case they have any. The results agree well with a hypothesis that serotonin receptors are dominant in the chemoreceptor trigger zone of monkeys.
Subject(s)
Antiemetics/pharmacology , Benzamides/pharmacology , Dopamine Antagonists/pharmacology , Dopamine D2 Receptor Antagonists , Radiation Injuries, Experimental/complications , Receptors, Serotonin/drug effects , Serotonin Antagonists/pharmacology , Vomiting/etiology , Animals , Antiemetics/therapeutic use , Benzamides/therapeutic use , Disease Models, Animal , Dopamine Antagonists/therapeutic use , Drug Evaluation, Preclinical , Female , Gamma Rays , Macaca fascicularis , Male , Radiation Injuries, Experimental/drug therapy , Receptors, Dopamine D2/drug effects , Receptors, Dopamine D2/radiation effects , Receptors, Serotonin/radiation effects , Receptors, Serotonin, 5-HT3 , Serotonin Antagonists/therapeutic use , Time Factors , Vomiting/drug therapy , Whole-Body IrradiationABSTRACT
In the experiments of dogs exposed to ionizing radiations at doses of 50 and 70 Gy, an essential role of the central mechanism in the origin of early postradiation vomiting has been confirmed. Insufficient efficiency of dimethpramide, a dophamynolytics, in this case may be connected either with initiation of other (non-dophamynosensitive) structures of the chemoreceptor trigger zone of with a growing role of the reflex way of vomiting arising due to a considerable intestinal injury that causes diarrhea. The inhibition of intestinal M-cholinoreceptors by methacine prevented diarrhea but didn't change the intensity of the vomiting reaction which, however, does not eliminate the possibility of afferentation from receptors that respond to others biologically active substances.
Subject(s)
Radiation Injuries, Experimental/complications , Vomiting/etiology , Whole-Body Irradiation/adverse effects , Acute Disease , Animals , Antiemetics/therapeutic use , Benzamides/therapeutic use , Benzilates/therapeutic use , Choline/analogs & derivatives , Choline/therapeutic use , Cholinergic Antagonists/therapeutic use , Dogs , Dopamine Antagonists/therapeutic use , Dose-Response Relationship, Radiation , Drug Evaluation, Preclinical , Drug Therapy, Combination , Electrons/adverse effects , Female , Male , Particle Accelerators , Radiation Injuries, Experimental/drug therapy , Random Allocation , Time Factors , Vomiting/prevention & controlABSTRACT
In experiments with thirty rabbits the influence of thirty-minute microwave irradiation (1.5 GHz, pulse intensity 0.3 mW/cm2; pulsed modes: 0.12 Hz, 16 ms or 1000 Hz, 0.4 ms; pack-pulsed mode: pulse frequency 1000 Hz, pack frequency 0.12 Hz) on the total bioelectrical activity of brain structures was studied. The reliable effect was detected only in hippocamp. The total bioelectrical activity of cortex, caudate nucleus, hypothalamus, amygdala and septum was not changed reliably in animal group studied. The reaction of hippocamp was displayed as amplification of theta-range in spectrum within of normal functioning.