[The morphological aspects of the protective action of enterosorbent K(2)9 during the use of the antitumor anthracycline antibiotic carminomycin]. / Morfologicheskie aspekty protektornogo deistviia énterosorbenta K(2)9 pri primenenii protivoopukholevogo antratsiklinovogo antibiotika karminomitsina.

The authors substantiate morphologically the protector effect of K(2)9 enterosorbent during its parallel use with the antitumour anthracyclin antibiotic carminomycin. The agent was administered intraperitoneally in animals at the maximum tolerable dose. Use of the K(2)9 enterosorbent reduces the cardiotoxic effect of carminomycin.

[Mutagenic effects of direct electric current]. / Mutagennyi éffekt postoiannogo élektricheskogo toka.

Mutagenic effect of direct electric current on sprouts of Vicia faba L. was detected. The effect manifested itself in increase in percentage of cells with chromosome aberrations in root meristem. The most considerable injuries are observed when root meristem contacts with the positive electrode during current passing. Typical peculiarity of mutagenic effect of current is appearance of dicentrics which exceed the control value 4 times. By the end of the first mitotic cycle, gradual reduction of percentage of injured cells, reaching the control value, is observed.

[Effect of different kinds of Ocean paste on rat liver biochemical indices in sodium fluoride poisoning]. / Vliianie razlichnzkh vidov pasty "Okean" na biokhimicheskie pokazateli pecheni krys pri intoksikatsii, vyzvannoi ftoridom natriia.

The paper is concerned with the effect of diets including three chemically different types of the "Ocean" paste on biochemical characteristics (glycolysis, the content of phosphofructokinase, dehydrogenase, glucoso-6- phosphate, demethylase, dimethylalaniline hydroxylase, ascorbic acid) of the liver of rats exposed to sodium fluoride overdosage. The test diets were compared with those containing conventional sources of protein (casein, beef). Acute exposure to sodium fluoride caused changes in the biochemical characteristics. The most appreciable changes were seen in the group of rats fed beef. As compared with control, the shifts in the biochemical characteristics were negligible provided the rats exposed to acute and chronic poisoning received the diet supplemented with the paste. No morphological changes were found in the internal organs. The data obtained indicate that the type C "Ocean" paste has a protective action in sodium fluoride poisoning.