ABSTRACT
OBJECTIVE: To evaluate the diagnostic efficacy of Qisexingtai hand diagnostic method in the diagnosis of coronary artery disease (CAD). METHODS: This was an investigator-initiated, prospective, multi-center, cross-sectional study. All the participants from three hospitals in China had been diagnosed by both Qisexingtai hand diagnostic method and coronary angiography. We compared the two diagnostic methods to calculate the sensitivity, the specificity, the omission diagnostic rate, the mistaken diagnostic rate and accuracy in order to evaluate the diagnostic efficacy of Qisexingtai hand diagnostic method for CAD. RESULTS: A total of 326 subjects were enrolled, diagnosed by both Qisexingtai hand diagnostic method and coronary angiography. As a result, there were 166 positive cases according to Qisexingtai hand diagnostic method, and 131 positive cases according to coronary angiography. Compared with the results of coronary angiography, the sensitivity of Qisexingtai hand dia-gnostic method was 80.2%, the specificity was 68.7%, the omission diagnostic rate was 19.8%, the mistaken diagnostic rate was 31.3%, and the accuracy was 73.3%. Area under the receiver operating characteristic curve was estimated as 0.735 for all, and 0.718, 0.735, 0.783 for the three sub-centers. CONCLUSION: Qisexingtai hand diagnostic method with high accuracy and sensitivity has certain application value in the diagnosis of CAD.
Subject(s)
Coronary Artery Disease , China , Coronary Angiography/methods , Coronary Artery Disease/diagnostic imaging , Cross-Sectional Studies , Humans , Prospective StudiesABSTRACT
In China and abroad, Traditional Chinese Medicine (TCM) have been applied and developed. That is depended on doctors and scholars of the past dynasties to inseparable from the inheritance, protection, development, and innovation of Traditional Knowledge of Chinese Medicine. With the progress of modern society and people's awareness of traditional culture protection, people are also improving the understanding of TCM. Through the analysis of the situation and significance of the protection of Traditional Knowledge of Chinese Medicine and the development of Japanese Kampo medicines, recognized that the development of Kampo medicines ignored the source. Their original intention and purpose of protection the Traditional Knowledge of Medicine are completely different from China. The protection of Traditional Knowledge of Chinese Medicine should be in accordance with the basic national conditions, and the system of the protection of Traditional Knowledge of Chinese Medicine should be formulated and perfected to ensure the sustainable development of TCM.
ABSTRACT
India is rich of traditional medicine knowledge. Due to inadequate protection on its traditional medicine knowledge, some of them have been illegally possessed or used by other countries, resulting in huge economic and cultural losses. In order to prevent such issues from happening, the Indian government has formulated a series of policies to protect and rationally develop traditional medicine knowledge, taken up many effective measures, such as collecting and archiving traditional medical knowledge, formulating laws and policies, establishing an administrative supervision system for traditional medicine knowledge, establish a Traditional Knowledge Digital Library (TKDL), as well as build a traditional medical knowledge registration and invention patent system. It also establishes an investment foundation, and conducts intellectual property culture building. At present, India has formed a relatively complete protection system for traditional medicine knowledge, which has achieved good results and gained recognition. To summarize the experience of traditional medicine knowledge protection in India can provide reference for China.
ABSTRACT
India is rich of traditional medicine knowledge. Due to inadequate protection on its traditional medicine knowledge, some of them have been illegally possessed or used by other countries, resulting in huge economic and cultural losses. In order to prevent such issues from happening, the Indian government has formulated a series of policies to protect and rationally develop traditional medicine knowledge, taken up many effective measures, such as collecting and archiving traditional medical knowledge, formulating laws and policies, establishing an administrative supervision system for traditional medicine knowledge, establish a Traditional Knowledge Digital Library (TKDL), as well as build a traditional medical knowledge registration and invention patent system. It also establishes an investment foundation, and conducts intellectual property culture building. At present, India has formed a relatively complete protection system for traditional medicine knowledge, which has achieved good results and gained recognition. To summarize the experience of traditional medicine knowledge protection in India can provide reference for China.
ABSTRACT
<p><b>OBJECTIVE</b>To develop an HPLC method for the quantification of six active components in three species (Swertia davidi, S. nervosa and S. mussotii) .</p><p><b>METHOD</b>The determination was performed on a Hypersil BDS colunm (4. 6 mm x 200 mm, 5 microm). Acetonitrile and 0.5% phosphoric acid solution were used as the mobile phases with a gradient elution. The flow rate was 1.0 mL x min(-1). The UV detection wavelength was at 240, 274, 325 and 334 nm. The column oven temperature was at 25 degrees C.</p><p><b>RESULT</b>Six components were separated commendably in 60 minutes. The calibration curves of swertiamarin, gentiopicroside, norswertianolin, swertianolin, demethylbellidifolin and bellidifolin were in good linearity over the range of 0.520-20.8, 0.202-8.06, 0.107-4.28, 0.097-3.86, 0.094-3.77, 0.101-4.02 microg, respectively (r = 0.999 9). The average recoveries were 98.7%, 98.1%, 98.3%, 98.8%, 98.1% and 98.6%, respectively, and the RSD were less than 3.0% (n = 6).</p><p><b>CONCLUSION</b>The method is accurate,simple and reproducible, and can be used to control the quality of Swertia.</p>