1.
Chembiochem
; 14(5): 564-7, 2013 Mar 18.
Article
in English
| MEDLINE
| ID: mdl-23483642
ABSTRACT
Ringing the changes: Selenazolines have applications in medicinal chemistry, but their synthesis is challenging. We report a new convenient and less toxic route to these heterocycles that starts from commercially available selenocysteine. The new route depends on a heterocyclase enzyme that creates oxazolines and thiazolines from serines/threonines and cysteines.