ABSTRACT
Based on data mining technology, the acupoints compatibility rules of acupuncture for depression diseases were explored. The randomized controlled trial (RCT) articles regarding acupuncture for depression diseases published from establishment of database to September 2nd, 2022 were searched in CNKI database, Wangfang database, VIP database, SinoMed database, PubMed, EMbase, Web of Science and Cochrane Library. The use frequency of acupoints, meridian tropism, selection of special acupoints and acupoint association rules for five common depression diseases, including primary depression, post-stroke depression, menopausal syndrome, psychoneurosis and anxiety disorder, were analyzed by Python programming language. Cytoscape software was used to analyze the acupoint association and the disease-acupoint co-occurrence network. As a result, totally 387 articles were included, and 319 acupoints prescriptions for the above five common depression diseases were extracted, involving 159 acupoints. The use frequency of acupoints was 2 574 times in total. The frequently-used acupoints were Baihui (GV 20), Sanyinjiao (SP 6), Taichong (LR 3), Neiguan (PC 6), Shenmen (HT 7), Yintang (GV 24+), Zusanli (ST 36), Hegu (LI 4), Sishencong (EX-HN 1) and Taixi (KI 3), etc. The frequently involved meridians were the governor vessel, foot-taiyang bladder meridian, foot-taiyin spleen meridian, and foot-jueyin liver meridian. The frequency of the special acupoints from high to low was crossing points, five-shu points, yuan-primary points, back-shu points, luo-connecting points, and eight confluent points, etc, which were often used in combination with "Baihui (GV 20)-Yintang (GV 24+)" (the highest degree of association). At the same time, the analysis of the co-occurrence network of depression diseases and acupoints showed that the core acupoints group of acupuncture for depression diseases were Baihui (GV 20), Taichong (LR 3), Shenmen (HT 7), Zusanli (ST 36), Neiguan (PC 6) and Sanyinjiao (SP 6). In conclusion, acupuncture treatment for depression diseases has gradually formed a rule of acupoint compatibility, with special acupoint as the main body and "unblocking the governor vessel, and regulating the spirit and qi " as the main therapeutic principle.
Subject(s)
Acupuncture Therapy , Meridians , Acupuncture Points , Data Mining , Depression , Randomized Controlled Trials as TopicABSTRACT
OBJECTIVE: To compare the contents of tanshinone IIA in Radix Salviae Miltorrhizae from different species, production places and collecting time, for study its quantity from Shandong. METHODS: HPLC method was used. RESULTS: The contents of tanshinone IIA in Radix Salviae Miltorrhizae of Shandong ranged from 0.330%-0.726%. CONCLUSION: Setting the contents of tanshinone IIA as index, the quantity of Salvia miltiorrhiza Bge. f. alba C. Y. Wu et H. W. L. is better than Salvia miltiorrhiza Bge.. The genuine production place-Mengyin is the best planting area; the plantable place is mountaing district hillyland. Planting in plain region is inadvisable; the best collecting time is middle September.
Subject(s)
Phenanthrenes/analysis , Plants, Medicinal/chemistry , Salvia miltiorrhiza/chemistry , Abietanes , China , Chromatography, High Pressure Liquid , Plant Roots/chemistry , Plants, Medicinal/growth & development , Rhizome/chemistry , Salvia miltiorrhiza/classification , Salvia miltiorrhiza/growth & development , SeasonsABSTRACT
OBJECTIVE: To provide evidence for identification of the morphology and histology of Pinellia pedatisecta Schott. METHODS: Using microscope and scanning electron microscope, characteristics of the Pinellia pedatisecta Schott. were studied comparatively. RESULTS: The surface of leaves, fruits, testa and pollen grain of the cultivated Pinellia pedatisecta Schott. showed different characteristics. CONCLUSION: The results of the study can be used for the identification of the Pinellia pedatisecta Schott. in Shandong.