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1.
Rev. Esc. Enferm. USP ; Rev. Esc. Enferm. USP;57: e20220324, 2023. tab, graf
Article in English, Portuguese | LILACS, BDENF - Nursing | ID: biblio-1440975

ABSTRACT

ABSTRACT Objective: To identify risk factors for mental health in the population in times of COVID-19 through the analysis of levels of socio-cognitive mindfulness and perception of stress in individuals. Method: This is a cross-sectional observational study with a quantitative approach, carried out through online data collection using the Perceived Stress Scale and the Langer Mindfulness Scale in a sample of 955 individuals from different regions of Brazil. Results: Women, younger people and individuals with low socioeconomic conditions had higher levels of perceived stress; on the other hand, older men and individuals with high socioeconomic status had higher levels of mindfulness. Conclusion: Socio-cognitive mindfulness was not a protective factor for perceived stress in the context of the COVID-19 pandemic.


RESUMEN Objetivo: Identificar factores de riesgo para la salud mental en la población en tiempos de COVID-19 a través del análisis de los niveles de mindfulness sociocognitivo y percepción de estrés en los individuos. Método: Se trata de un estudio observacional transversal con enfoque cuantitativo, realizado a través de la recolección de datos en línea utilizando la Escala de Estrés Percibido y la Escala de Mindfulness de Langer en una muestra de 955 individuos de diferentes regiones de Brasil. Resultados: Las mujeres, los jóvenes y las personas con condiciones socioeconómicas bajas presentaron mayores niveles de estrés percibido. Por el contrario, los hombres mayores y las personas con un nivel socioeconómico alto tenían niveles más altos de atención plena. Conclusión: El mindfulness sociocognitivo no fue un factor protector para el estrés percibido en el contexto de la pandemia de COVID-19.


RESUMO Objetivo: Identificar fatores de risco para a saúde mental na população em tempos de COVID-19 por meio da análise dos níveis atenção plena sociocognitiva e de percepção ao estresse nos indivíduos. Método: Trata-se de um estudo observacional do tipo transversal com abordagem quantitativa, realizado por meio de coleta de dados online utilizando a Escala de Estresse Percebido e a Escala de Atenção Plena de Langer em uma amostra de 955 indivíduos de diversas regiões do Brasil. Resultados: Mulheres, pessoas mais jovens e indivíduos com baixas condições socioeconômicas apresentaram maiores níveis de estresse percebido. Em contrapartida, os homens mais velhos e indivíduos com altas condições socioeconômicas apresentaram maiores níveis de atenção plena. Conclusão: A atenção plena sociocognitiva não se constituiu fator de proteção ao estresse percebido no contexto pandêmico da COVID-19.


Subject(s)
Mental Health , Nursing , Coronavirus Infections , Stress, Psychological , Mindfulness , COVID-19
2.
Biofouling ; 34(7): 815-825, 2018 08.
Article in English | MEDLINE | ID: mdl-30322278

ABSTRACT

This study evaluated the antibacterial activity of terpinen-4-ol against Streptococcus mutans and Lactobacillus acidophilus and its influence on gbpA (S. mutans) and slpA (L. acidophilus) gene expression. As measured by XTT assay, the concentrations of terpinen-4-ol that effectively inhibited the biofilm were 0.24% and 0.95% for S. mutans and L. acidophilus, respectively. Confocal microscopy revealed the presence of a biofilm attached to the enamel and dentin block surfaces with significant terpinen-4-ol effects against these microorganisms. The expression of the gbpA and slpA genes involved in adherence and biofilm formation was investigated using RT-PCR. Expression of these genes decreased after 15 min with 0.24% and 0.95% terpinen-4-ol in S. mutans and L. acidophilus, respectively. These findings demonstrate the antimicrobial activity of terpinen-4-ol and its ability to modulate the expression of gbpA and slpA genes, emphasizing the therapeutic capacity of terpinen-4-ol as an alternative to inhibit adherence in biofilm.


Subject(s)
Anti-Bacterial Agents/pharmacology , Dental Caries/prevention & control , Lactobacillus acidophilus/drug effects , Streptococcus mutans/drug effects , Terpenes/pharmacology , Adult , Anti-Infective Agents , Bacterial Proteins/genetics , Bacterial Proteins/metabolism , Biofilms/drug effects , Humans , Lactobacillus acidophilus/genetics , Lactobacillus acidophilus/metabolism , Male , Microbial Sensitivity Tests , Phytotherapy , Streptococcus mutans/genetics , Streptococcus mutans/metabolism , Tea Tree Oil/chemistry
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