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J Postgrad Med ; 70(2): 105-108, 2024 Apr 01.
Article in English | MEDLINE | ID: mdl-38629272

ABSTRACT

ABSTRACT: Arsenic compounds are colorless and odorless and toxicity can occur either acutely following ingestion of arsenicals with gastrointestinal disturbances or due to chronic exposure usually presenting with dermatologic lesions and peripheral neuropathy. We report a young couple who presented with signs and symptoms of painful sensorimotor peripheral neuropathy in a typical "stocking and glove" pattern. They had raised urinary arsenic levels with normal blood levels and thus, a diagnosis of chronic arsenic poisoning due to contaminated water intake was made after detecting elevated arsenic levels in their home water supply. Both patients underwent chelation therapy with dimercaprol for 14 days and reported subjective and objective improvement in symptoms with the reduction in urinary arsenic levels at the end of therapy.


Subject(s)
Arsenic Poisoning , Peripheral Nervous System Diseases , Humans , Arsenic/urine , Arsenic Poisoning/complications , Chelating Agents/therapeutic use , Chelation Therapy , Chronic Disease , Dimercaprol/therapeutic use , Peripheral Nervous System Diseases/chemically induced , Treatment Outcome
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