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Int J Mol Sci ; 22(13)2021 Jun 29.
Article in English | MEDLINE | ID: mdl-34209728

ABSTRACT

Parental behaviour is a comprehensive set of neural responses to social cues. The neural circuits that govern parental behaviour reside in several putative nuclei in the brain. Melanin concentrating hormone (MCH), a neuromodulator that integrates physiological functions, has been confirmed to be involved in parental behaviour, particularly in crouching behaviour during nursing. Abolishing MCH neurons in innate MCH knockout males promotes infanticide in virgin male mice. To understand the mechanism and function of neural networks underlying parental care and aggression against pups, it is essential to understand the basic organisation and function of the involved nuclei. This review presents newly discovered aspects of neural circuits within the hypothalamus that regulate parental behaviours.


Subject(s)
Hypothalamus/cytology , Nerve Net/physiology , Nesting Behavior/physiology , Aggression/psychology , Animals , Behavior, Animal/physiology , Hypothalamic Hormones/genetics , Hypothalamic Hormones/physiology , Hypothalamus/physiology , Male , Melanins/genetics , Melanins/physiology , Mice , Mice, Knockout , Pituitary Hormones/genetics , Pituitary Hormones/physiology
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