ABSTRACT
Quantitative imaging biomarkers of liver disease measured by using MRI and US are emerging as important clinical tools in the management of patients with chronic liver disease (CLD). Because of their high accuracy and noninvasive nature, in many cases, these techniques have replaced liver biopsy for the diagnosis, quantitative staging, and treatment monitoring of patients with CLD. The most commonly evaluated imaging biomarkers are surrogates for liver fibrosis, fat, and iron. MR elastography is now routinely performed to evaluate for liver fibrosis and typically combined with MRI-based liver fat and iron quantification to exclude or grade hepatic steatosis and iron overload, respectively. US elastography is also widely performed to evaluate for liver fibrosis and has the advantage of lower equipment cost and greater availability compared with those of MRI. Emerging US fat quantification methods can be performed along with US elastography. The author group, consisting of members of the Society of Abdominal Radiology (SAR) Liver Fibrosis Disease-Focused Panel (DFP), the SAR Hepatic Iron Overload DFP, and the European Society of Radiology, review the basics of liver fibrosis, fat, and iron quantification with MRI and liver fibrosis and fat quantification with US. The authors cover technical requirements, typical case display, quality control and proper measurement technique and case interpretation guidelines, pitfalls, and confounding factors. The authors aim to provide a practical guide for radiologists interpreting these examinations. © RSNA, 2023 See the invited commentary by Ronot in this issue. Quiz questions for this article are available in the supplemental material.
Subject(s)
Elasticity Imaging Techniques , Iron Overload , Liver Diseases , Humans , Iron , Liver Cirrhosis/diagnostic imaging , Liver Cirrhosis/pathology , Liver/diagnostic imaging , Liver/pathology , Magnetic Resonance Imaging/methods , Liver Diseases/pathology , Iron Overload/diagnostic imaging , Elasticity Imaging Techniques/methods , Radiologists , BiomarkersABSTRACT
OBJECTIVE: The purpose of this article is to present our experience using multimodality interventional radiologic techniques for the treatment of cancer-related pain across a spectrum of abnormalities. CONCLUSION: Percutaneous imaging-guided thermal ablation has emerged as a safe and efficacious treatment for painful osseous metastases. The implementation of interventional thermal ablative techniques for the treatment of intractable pain secondary to malignancy can be further expanded to include transcatheter and combination procedures.