ABSTRACT
Hypnotherapy has emerged as a potential alternative to improve exclusive breastfeeding rates, particularly in countries like Indonesia where they are below optimal levels. This study aims to evaluate the impact of audio hypnotherapy on the psychological, exclusive breastfeeding behavior, the OXTR protein and mRNA expression gene OXTR in mothers of infants aged 0-6 months. This study employed a Pragmatic Randomized Controlled Trial design, conducted from November 2022 to May 2023 in 11 primary health centers. The study population included breastfeeding mothers with infants aged 0-6 months, with a total sample size of 70 respondents who were randomly divided into intervention (received audio hypnotherapy) and control groups (received standard care). The psychological condition was measured using the Depression Anxiety Stress Scale. Exclusive breastfeeding behavior was assessed based on both quality and quantity. Genetic factors were evaluated through mRNA OXTR expression using real-time PCR and protein OXTR levels using ELISA. Analyzing data using linear and logistic regression models. Both bivariate and multivariate analyses revealed significant differences in psychological condition (p < .0001). There were big differences in the exclusive breastfeeding behavior (p < .0001), as well as in the amounts of protein OXTR and mRNA expression of the OXTR gene (p < .0001). We recommend the implementation of audio hypnotherapy as an effective complementary therapeutic approach to manage the psychological well-being, exclusive breastfeeding behavior, the mRNA expression of the OXTR gene and levels of OXTR protein in mothers of infants aged 0-6 months.
Subject(s)
Breast Feeding , Hypnosis , RNA, Messenger , Receptors, Oxytocin , Humans , Female , Adult , Hypnosis/methods , Receptors, Oxytocin/genetics , Infant , RNA, Messenger/genetics , Infant, Newborn , Mothers/psychology , IndonesiaABSTRACT
Background: Male infertility accounts for â¼50% of all infertility cases. The reasons for male infertility may vary, and one of them is related to an idiopathic factor that may impair spermatogenesis. Acupuncture is one of the most well-known and widely accepted alternative treatments and is becoming known as an effective complementary therapy for infertility. Case: The case in this article demonstrated the effectiveness of electroacupuncture (EA) for improving male fertility by referring to the total motile sperm count (TMSC), sperm morphology and motility, DNA Fragmentation Index (DFI) of the sperm before and after EA, and pregnancy success in a couple with male infertility. Couples are given therapy with EA twice per week for up to 12 sessions and planned intercourse during the fertile period (ovulation). After planned intercourse, the wife became pregnant; an intrauterine gestational sac (GS) was seen on transvaginal ultrasound and her human chorionic gonadotropin urine test was positive. Results: The TMSC parameter, sperm morphology and sperm motility, post-EA DFI was improved, compared to pre-EA. The couple was became pregnant after undergoing EA 12 times to treat male infertility. Conclusions: This case illustrated that EA therapy for idiopathic male infertility has an effect toward improvement of the spermiogram test result, DFI, and success in achieving a pregnancy. However, further research is needed because there are many patients with different causes for their infertility.
ABSTRACT
An RCT on the efficacy of hypnosis in improving adherence to antituberculosis treatment using the Health Belief Model (HBM). Sixty study subjects were sampled at random from tuberculosis patients who visited the Center for Pulmonary Community Health in Solo, Indonesia. Hypnotherapy with posthypnotic suggestions was delivered once a week over 6 months. The data on pretested 7 HBM constructs were analyzed using t test and path analysis. Hypnotherapy had a positive effect on perceived susceptibility, seriousness, threat, benefit, and self-efficacy. It indirectly had a positive effect on adherence. Hypnotherapy had a negative effect on perceived barrier. This study supports the hypothesis that hypnotherapy effectively improves adherence to tuberculosis treatment, by enhancing health-related perception and beliefs in the HBM.