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Am J Trop Med Hyg ; 109(6): 1238-1241, 2023 12 06.
Article in English | MEDLINE | ID: mdl-37962328

ABSTRACT

The clinical manifestations of leptospirosis range from mild to life-threatening and can impact on multiple organ systems. A wide array of neurological manifestations of leptospirosis have been reported, although the pathophysiology of neuroleptospirosis remains incompletely understood. We present a case of leptospirosis complicated by bilateral sensorineural deafness, with nodular meningitis demonstrated in the internal auditory meatus on magnetic resonance imaging. The patient was treated with doxycycline, ceftriaxone, systemic and topical steroids, and hyperbaric oxygen therapy, with modest, but incomplete, improvement.


Subject(s)
Hearing Loss, Sensorineural , Hyperbaric Oxygenation , Leptospirosis , Humans , Ceftriaxone/therapeutic use , Hearing Loss, Bilateral/etiology , Hearing Loss, Sensorineural/etiology , Hearing Loss, Sensorineural/drug therapy , Hyperbaric Oxygenation/methods , Leptospirosis/complications , Leptospirosis/diagnosis , Leptospirosis/drug therapy , Male , Middle Aged , Dexamethasone/therapeutic use , Doxycycline/therapeutic use , Treatment Outcome
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