ABSTRACT
The compound of active ingredients of traditional Chinese medicine (TCM),whose material base is relatively clear,adheres to the concept and advantages of formula compatibility of TCM.Thus,it is an important approach to modern TCMresearch.The significance of research on compound of TCMcomponents/ingredients,as well as the research ideas,is sketched out,and the current research on compound of TCMcomponents for the prevention and treatment of liver diseases is reviewed.The research strategies for TCMcomposition/compound for the prevention and treatment of liver diseases are elucidated from the following two aspects:exploring the compound of TCM components based on clinical TCM compound and studying the composition aiming at the effective components or ingredients of TCM that have been known;it is pointed out that the compatibility of effective TCM components,which provides the method and technology system for innovative drug research,is an innovative research model for inheriting and developing the TCMtheory and is one of the important approaches to modern TCM research.
ABSTRACT
Systems biology, which includes genomics, proteomics, transcriptomics and metabolomics, is an integration of system theory and biology. It studies the life phenomena with thinking method of systems theory. And it provides an important methodological basis and technical conditions for recognizing syndrome of traditional Chinese medicine (TCM) and mechanism of therapeutic effect from multiple disciplines and perspectives. Systems biology is similar to the core idea of TCM system and holism concept. Therefore, systems biology can be used as a platform and pivot of non-alcoholic fatty liver disease (NAFLD) in modern TCM study. Systems biology will accelerate the modernization research of TCM in the prevention and treatment of NAFLD. It will also provide new ideas and methods for TCM study on NAFLD.
ABSTRACT
This article was aimed to expound current complexity and diversity about Chinese medicine dose-ef-fect relationship . It demonstrated that the study on Chinese medicine dose-effect relationship should be based on clinical effect as its foundation , and be guided by the traditional Chinese medicine ( TCM ) theories . Differ-ent modern science and technology means and methods should be applied for the multi-perspective , multi-lev-el and multidisciplinary systematic study of the Chinese medicine dose-effect relationship .