ABSTRACT
Lipemia retinalis is an unusual ocular finding associated with hypertriglyceridemia. We report the case of an infant treated for retinopathy of prematurity who later developed lipemia retinalis, with triglyceride levels of 4736 mg/dl. There was a paradoxical worsening of hypertriglyceridemia with the use of medium chain triglyceride supplement. On discontinuing the supplement, the triglycerides level drastically dropped, and retinal vasculature returned to a normal hue.
Subject(s)
Diet, High-Fat/adverse effects , Hypertriglyceridemia/etiology , Laser Coagulation , Retinal Diseases/etiology , Retinopathy of Prematurity/surgery , Triglycerides/adverse effects , Female , Food, Formulated , Humans , Hypertriglyceridemia/diagnosis , Infant Food , Infant, Newborn , Retinal Diseases/diagnosis , Retinal Vessels/pathologyABSTRACT
We describe the use of optical coherence tomography angiography (OCTA) in detecting and monitoring regression of the neovascular complex (NVC) in a case of aggressive posterior retinopathy of prematurity (AP-ROP). A premature Asian Indian girl with AP-ROP underwent laser photoablation at 26 days of life. Persistent NVC at the posterior border of the lasered retinal bed was detected clinically. On en face spectral domain optical coherence tomography (SD-OCT) and OCTA, the NVC appeared as an arborizing vascular net in the superficial capillary plexus. The deep capillary plexus and outer retinal layers showed corresponding flow outlines that suggested deeper extensions of the lesion. Supplemental laser treatment of the NVC was performed. Ten days later repeat en face SD-OCT and OCTA of the identical retinal location revealed that the vascular tortuosity and dilatation had reduced and that the flow lesions in the deeper layers were undetectable. Our findings in this case suggest that the NVC in AP-ROP extends beyond the superficial retina.
Subject(s)
Fluorescein Angiography , Retinal Neovascularization/diagnosis , Retinal Vessels/pathology , Retinopathy of Prematurity/diagnosis , Tomography, Optical Coherence/methods , Female , Gestational Age , Humans , Infant, Newborn , Infant, Very Low Birth Weight , Laser Coagulation , Lasers, Solid-State/therapeutic use , Retinal Neovascularization/surgery , Retinopathy of Prematurity/surgeryABSTRACT
OBJECTIVE: To report a case of toxic anterior uveitis probably secondary to the use of topical podophyllum. DESIGN: Case report, interventional. METHODS: The authors present a 78-year-old male with acute anterior uveitis that developed within a couple of hours of application of topical podophyllum. In vivo confocal microscopy showed unique findings that disappeared following treatment with topical steroids alone. The patient reapplied podophyllum 2 months later and a recurrence of uveitis was noted. RESULTS: A score of 7 was obtained using the adverse drug reaction probability scale, suggesting that the anterior uveitis is a probable adverse reaction to topical podophyllum. CONCLUSIONS: Anterior uveitis may occur after topical application of podophyllum.