1.
Brain Res Dev Brain Res
; 91(2): 300-3, 1996 Feb 26.
Article
in English
| MEDLINE
| ID: mdl-8852382
ABSTRACT
Developmental expression of the estrogen receptor (ER) in rat hypothalamus was examined using immunohistochemistry. In the medial preoptic nucleus and ventromedial nucleus ER-immunoreactivity was detected as early as E17, whereas ER protein expression in the periventricular preoptic nucleus and arcuate nucleus was delayed until E19. These results show that following a region specific onset of the ER protein expression sex differences in ER levels are already detectable during the perinatal period.