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Farmakol Toksikol ; 48(6): 49-53, 1985.
Article in Russian | MEDLINE | ID: mdl-4085630

ABSTRACT

Material is presented on combined effects of mm-band radio waves and cyclophosphane on the hemopoietic system and inoculated tumor sarcoma-180. The role of the bone marrow truncal cells in the acceleration of regenerative processes and a two-fold increase of clonogenic activity of the bone marrow were determined in the combined group in comparison with the bone marrow of animals receiving just the preparation. The sensitizing effect of mm-waves in combination with cyclophosphane was distinctly manifested after two courses of administration of the preparation, leading to 85-100% resorption of the tumours without further relapses during the year of observation over the animals.


Subject(s)
Cyclophosphamide/therapeutic use , Hematopoiesis/drug effects , Microwaves/therapeutic use , Animals , Bone Marrow/drug effects , Bone Marrow/physiopathology , Bone Marrow/radiation effects , Colony-Forming Units Assay , Combined Modality Therapy , Drug Evaluation, Preclinical , Hematopoiesis/radiation effects , Mice , Mice, Inbred C57BL , Mice, Inbred CBA , Neoplasm Transplantation , Sarcoma 180/physiopathology , Sarcoma 180/therapy , Time Factors
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