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Ann Pharm Fr ; 80(1): 76-80, 2022 Jan.
Article in French | MEDLINE | ID: mdl-33878309

ABSTRACT

This is a case of voluntary ingestion of Nerium oleander leaves in an adolescent requiring the use of atropine and emergency chartering of antidigoxin antibodies (Digifab®) due to the difficulty of assessing oleandrin level and associated toxicity. Upon hospital admission, a digoxinemia was performed (0.44µg/mL) and the presence of oleandrine was detected. Oleandrin levels at toxic levels may be suspected by a measure of blood digoxin and explain the patient's clinical signs, which could adapt the therapeutic management.


Subject(s)
Cardenolides/poisoning , Digoxin/poisoning , Nerium , Adolescent , Humans , Nerium/poisoning , Plant Leaves/poisoning
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