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1.
Acta Psychol (Amst) ; 245: 104240, 2024 May.
Article in English | MEDLINE | ID: mdl-38569321

ABSTRACT

In our study, we use the post-hypnotic suggestion of easy remembering to improve memory with long-lasting effects. We tested 24 highly suggestible participants in an online study. Participants learned word lists and recalled them later in a recognition memory task. At the beginning of the study, participants were hypnotized and the post-hypnotic suggestion to remember easily was associated with a cue that participants used during the recognition memory task. In a control condition, the same participants used a neutral cue. One week later, participants repeated both conditions with new word lists. Participants were significantly faster and more confident in their recognition ratings in the easy-remembering condition compared to the control condition, and this effect persisted over one week. Crucially, the increased speed and confidence in the easy-remembering condition did not affect memory accuracy. That makes our hypnosis intervention promising for patients experiencing subjective memory impairments. APA PSYCINFO CODES: 2343 (Learning and Memory), 2380 (Consciousness States), 3351 (Clinical Hypnosis).


Subject(s)
Hypnosis , Suggestion , Humans , Learning , Mental Recall
2.
Hua Xi Kou Qiang Yi Xue Za Zhi ; 42(1): 19-27, 2024 Feb 01.
Article in English, Chinese | MEDLINE | ID: mdl-38475947

ABSTRACT

At present, the commonly used clinical protocols of oral comestic restoration are mostly based on the aesthetic indicators proposed by Western developed countries (referred to as Western aesthetics). Mechanically copying the Western aesthetic scheme, ignoring the difference between it and the Chinese oral aesthetic indicators (referred to as Chinese aesthetics), is unable to effectively support personalized cosmetic restoration diagnosis and treatment. In addition, new technologies and new solutions for cosmetic restoration, which are developing rapidly in recent years, are emerging one after another, but many popular concepts are confusing and lack of proper hierarchical diagnosis and treatment norms, and there is indeed an urgent need for discussion and clarity. From the perspective of serving clinical application, this paper discusses the deficiencies of the Chinese translation of the word "aesthetics", the diffe-rence and connection between aesthetics and cosmetology, and the relationship between cosmetic restoration and fixed restoration. It also discusses the difference between anterior teeth, esthetic zone and exposed zone, the diagnostic and therapeutic value of oral aesthetic analysis, as well as the application methods of desensitization, suggestion, and other therapies in difficult oral cosmetic restoration cases. We further introduce the decision tree and the clinical pathway for restoration and reconstruction of teeth in exposed zone guided by aesthetic analysis, and introduce the clinical process of aesthetic analysis and evaluation, the clinical triclassification of oral cosmetic restoration, and the corresponding clinical classification diagnosis and treatment points.


Subject(s)
Critical Pathways , Esthetics, Dental , Dental Implantation, Endosseous , Decision Trees
3.
BJA Educ ; 24(4): 121-128, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38481420
4.
Sci Rep ; 14(1): 3548, 2024 02 12.
Article in English | MEDLINE | ID: mdl-38347065

ABSTRACT

Effective coping with acute stress is important to promote mental health and to build stress resilience. Interventions improving stress coping usually require long training periods. In this study, we present a hypnosis-based intervention that produces long-term effects after a single hypnosis session. In that session, we established a post-hypnotic safety suggestion that participants can activate afterwards with a cue, the Jena Safety Anchor. We tested 60 participants in our study who all received the hypnosis session and a stress task. The safety group used the Jena Safety Anchor during acute stress (Trier Social Stress Test, TSST). The control group used a neutral anchor. We measured subjective stress responses via self-reports and physiological stress responses via saliva and blood samples as well as heart rate. One week later, all participants filled in an online survey to measure long-term effects of the post-hypnotic safety suggestion. We found that participants using the Jena Safety Anchor during the TSST reported significantly lower stress compared to the control group. The safety group also reported significantly fewer negative thoughts concerning their TSST performance than the control group during the stress recovery phase and 1 week later. All participants indicated that the Jena Safety Anchor still worked 1 week after its establishment. Suggestibility did not affect the efficacy of the Jena Safety Anchor. Our findings demonstrate that post-hypnotic safety suggestions improve stress coping with long-lasting effects, which makes it a promising intervention to promote mental health and establish stress resilience in just one hypnosis session.


Subject(s)
Hypnosis , Suggestion , Humans , Surveys and Questionnaires , Self Report , Coping Skills
5.
Psychol Sport Exerc ; 72: 102602, 2024 May.
Article in English | MEDLINE | ID: mdl-38280537

ABSTRACT

Differences in expectations between experimental and control groups can influence the outcomes of exercise interventions, emphasizing the need to match expectations across study groups. This online study examined whether the expectations to improve the performance of different cognitive tasks differ between various activities commonly used in research on the effects of exercise and cognitive function. Two hundred and five middle-aged adults performed two reaction-time tasks and one memory task. They were then asked to rate, on a 1-5 Likert scale, their expectations to improve performance in those tasks should they engage in six types of activities for three months: brisk walking, resistance exercise, stretching and balance exercises, watching videos with lectures on art, history, and science, a program of relaxation techniques, and yoga/tai chi/meditation. Results revealed that the highest expectations for improvement were associated with relaxation techniques and yoga/tai chi/meditation. Some activities, such as brisk walking and stretch and balance exercises, shared similar expectations. Previous knowledge of the possible beneficial effects of exercise on cognitive performance also led to higher expectations. To establish causal relationships, researchers should strive to use activities that share similar expectations to improve performance for the experimental and control groups. The findings of this study provide such activity pairs. Finally, researchers should also try to match participants with and without prior knowledge of the benefits of exercise to cognitive function between experimental and control groups.


Subject(s)
Exercise , Yoga , Adult , Middle Aged , Humans , Control Groups , Walking , Cognition
6.
Int J Clin Exp Hypn ; 72(1): 64-83, 2024.
Article in English | MEDLINE | ID: mdl-38060715

ABSTRACT

The author proposes that hypnosis is a culture-bound concept that has misattributed - to suggestion and hypnosis - the functioning of a natural, freestanding, human ability to alter personal experience. The 18th-century attribution of these phenomena (to the suggestions of a magnetizer) continues today because science and Western culture still do not explicitly acknowledge that humans possess a natural capacity to intentionally alter their own experiences. Like every other human ability (e.g. athletic, artistic, musical, mathematical, etc.), utilization of the natural human ability to intentionally alter one's personal experience does not require suggestion, trance, or hypnotic induction. This ability has been studied for over 200 years under the conceptual aegis of suggestibility and hypnosis. As a consequence, the phenomena of this freestanding ability have been veiled and conflated with hypnosis, suggestion, suggestibility, and hypnotizability. One serious consequence of this conflation is an underdeveloped, nomological network of hypnosis-centric concepts that has impeded the integration of hypnosis with the rest of science.


Subject(s)
Hypnosis , Humans , Suggestion
7.
Gen Hosp Psychiatry ; 86: 92-102, 2024.
Article in English | MEDLINE | ID: mdl-38154334

ABSTRACT

OBJECTIVE: Functional neurological disorder (FND) involves the presence of neurological symptoms that cannot be explained by neurological disease. FND has long been linked to hypnosis and suggestion, both of which have been used as treatments. Given ongoing interest, this review examined evidence for the efficacy of hypnosis and suggestion as treatment interventions for FND. METHOD: A systematic search of bibliographic databases was conducted to identify group studies published over the last hundred years. No restrictions were placed on study design, language, or clinical setting. Two reviewers independently assessed papers for inclusion, extracted data, and rated study quality. RESULTS: The search identified 35 studies, including 5 randomised controlled trials, 2 non-randomised trials, and 28 pre-post studies. Of 1584 patients receiving either intervention, 1379 (87%) showed significant improvements, including many who demonstrated resolution of their symptoms in the short-term. Given the heterogeneity of interventions and limitations in study quality overall, more formal quantitative synthesis was not possible. CONCLUSIONS: The findings highlight longstanding and ongoing interest in using hypnosis and suggestion as interventions for FND. While the findings appear promising, limitations in the evidence base, reflecting limitations in FND research more broadly, prevent definitive recommendations. Further research seems warranted given these supportive findings.


Subject(s)
Conversion Disorder , Hypnosis , Humans , Conversion Disorder/therapy , Dissociative Disorders/therapy , Nervous System Diseases/therapy
8.
Conscious Cogn ; 115: 103569, 2023 10.
Article in English | MEDLINE | ID: mdl-37660419

ABSTRACT

This study examined whether and how emotional hypnotic suggestions modulate the visual recognition of negative words. We investigated the influence of hypnotic suggestions aimed at modifying emotional reactivity on the arousal effect in negative words. High and low suggestible individuals performed a go/no-go lexical decision task in three intra-individual conditions: with a suggestion to increase emotional reactivity, with a suggestion to decrease emotional reactivity and without hypnotic suggestion. Results showed that hypnotic suggestions modulated the arousal facilitation effect differently depending on the level of suggestibility of the participants. In high suggestible individuals, response times for low-arousal negative words varied oppositely according to the suggestion administered, while no modulations were retrieved for high-arousal ones. In contrast, no suggestion effects were found for low suggestible participants. Altogether, these findings suggest a higher influence of hypnotic suggestions on emotional words that require longer processing times in high suggestible individuals.


Subject(s)
Hypnosis , Humans , Suggestion , Arousal/physiology , Recognition, Psychology , Reaction Time
9.
J Pain ; 24(12): 2153-2161, 2023 Dec.
Article in English | MEDLINE | ID: mdl-37394049

ABSTRACT

Two common elements in patient care are reoccurring painful events (eg, blood draws) and verbal suggestions from others for lessened pain. Research shows that verbal suggestions for lower pain can decrease subsequent pain perception from novel noxious stimuli, but it is less clear how these suggestions and prior painful experiences combine to influence the perception of a reoccurring painful event. The presented experiment tested the hypothesis that the order of these 2 factors influence pain perception for a reoccurring painful event. All participants (702 healthy college-student volunteers, 58% women, 85.5% White) experienced a novel painful event on one arm, then again on their other arm (now a familiar pain event). Participants who received the suggestion that they can tolerate more pain on the second arm relative to the first from the outset, before the initial pain event, perceived relatively less pain during the repeated event as compared to participants who received the same suggestion after the first painful event or no-suggestion (control). Given many pain events within medical contexts are, or become, familiar to patients, further researching the timing at which patients receive verbal suggestions for lower pain can inform practices to optimize the therapeutic, pain-reducing potential of such suggestions. PERSPECTIVE: Providing suggestions that a familiar pain event (ie, the second of 2) will be less painful than a prior event can reduce perceived pain for the familiar event depending on when it is presented. These findings can inform practices to optimize the therapeutic potential of verbal suggestions for reduced pain.


Subject(s)
Pain Perception , Pain , Humans , Female , Male , Pain/drug therapy , Suggestion , Pain Measurement
10.
Medicentro (Villa Clara) ; 27(2)jun. 2023.
Article in Spanish | LILACS | ID: biblio-1440538

ABSTRACT

Introducción: Se conocen diversos tratamientos para tratar y curar la depresión. Entre los más utilizados se encuentran la psicoterapia y la medicación. La hipnosis clínica utiliza un discurso basado en la sugestión y en los reflejos condicionados del sueño, para lograr la estabilidad en la desregulación del ciclo sueño / vigilia, lo cual es un factor esencial en el tratamiento de las personas deprimidas por la COVID-19. Objetivo: Comparar la evolución en la calidad y cantidad de sueño en pacientes con depresión post-COVID que fueron tratados con medicación e hipnosis. Métodos: Se realizó un estudio explicativo-comparativo, y un diseño cuasi-experimental. La muestra fue de 40 pacientes que fueron ingresados en el Hospital Universitario Clínico Quirúrgico «Cmdte. Manuel Fajardo Rivero», de Santa Clara, entre enero y marzo de 2021, con COVID-19. En un grupo de pacientes se empleó el inventario de depresión de Beck y un cuestionario para evaluar la cantidad y calidad del sueño antes y después de la intervención con medicación; en el otro grupo se empleó la hipnosis. Se utilizó la estadística descriptiva. Resultados: En ambos grupos la terapia empleada fue efectiva, redujo los niveles de depresión y eliminó las alteraciones del sueño. Conclusiones: Ambas formas de tratamiento se pueden emplear para tratar la depresión y los desórdenes propios del sueño. El método sugestivo de despertar de sueño hipnótico a sueño natural fue tan efectivo como los psicofármacos empleados.


Introduction: various treatments are known to treat and cure depression. Psychotherapy and medication are among the most used. Clinical hypnosis uses a discourse based on suggestions and conditioned sleep reflexes to achieve stability in sleep-wake cycle dysregulation, which is an essential factor in the treatment of people depressed by COVID-19. Objective: to compare the evolution in sleep quality and quantity in patients with post-COVID depression who were treated with medication and hypnotherapy. Methods: an explanatory comparative study with a quasi-experimental design was carried out. The sample consisted of 40 patients who were admitted due to COVID-19 at "Cmdte. Manuel Fajardo Rivero" Clinical and Surgical University Hospital from Santa Clara between January and March 2021. Beck Depression Inventory and a questionnaire were used in a group of patients to assess the sleep quality and quantity before and after the intervention with medication; hypnosis was used in the other group. Descriptive statistics was also used. Results: the used therapy was effective in both groups, reduced levels of depression and eliminated sleep disturbances. Conclusions: both forms of treatment can be used to treat depression and sleep disorders. The suggestive method of awakening from hypnotic sleep to natural sleep was as effective as the psychoactive drugs used.


Subject(s)
Psychotropic Drugs , Suggestion , Depression , Hypnosis
11.
Zhongguo Zhong Yao Za Zhi ; 48(3): 608-613, 2023 Feb.
Article in Chinese | MEDLINE | ID: mdl-36872223

ABSTRACT

This paper introduced the overview of the "eight trends" of Chinese medicinal materials(CMM) industry in 2021, analyzed the problems of CMM production, and put forward development suggestions. Specifically, "eight trends" could be summarized as follows.(1) The growing area of CMM tended to be stable, and some provinces began to release the local catalog of Dao-di herbs.(2) The protection process of new varieties accelerated, and a number of excellent varieties were bred.(3) The theory of ecological cultivation was further enriched, and the demonstration effect of ecological cultivation technology was prominent.(4) Some CMM realized complete mechanization and formed typical model cases.(5) The number of cultivation bases using the traceability platform increased, and provincial internet trading platforms were set up.(6) The construction of CMM industrial clusters accelerated, and the number of provincial-level regional brands increased rapidly.(7) Many new agricultural business entities were founded nationwide, and a variety of methods were used to drive the intensified development of CMM.(8) A number of local TCM laws were promulgated, and the management regulation of food and medicine homology substances catalogs was issued. On this basis, four suggestions for CMM production were proposed.(1) It is suggested to speed up the formulation of the national catalog of Dao-di herbs and carry out the certification of Dao-di herbs production bases.(2) Ecological planting of forest and grassland medicine should be further strengthened in terms of technical research and promotion based on the principle of ecological priority.(3) The basic work of disaster prevention should be paid more attention and technical measures for disaster mitigation should be developed.(4) The planted area of commonly used CMM should be incorporated into the national regular statistical system.


Subject(s)
Commerce , Industry , Agriculture , Certification , China
12.
Conscious Cogn ; 108: 103473, 2023 02.
Article in English | MEDLINE | ID: mdl-36706563

ABSTRACT

Bodily awareness is informed by both sensory data and prior knowledge. Although misleading sensory signals have been repeatedly shown to affect bodily awareness, only scant attention has been given to the influence of cognitive variables. Hypnotic suggestion has recently been shown to impact visuospatial and sensorimotor representations of body-part size although the mechanisms subserving this effect are yet to be identified. Mental imagery might play a causal or facilitative role in this effect, as it has been shown to influence body awareness in previous studies. Nonetheless, current views ascribe only an epiphenomenal role to imagery in the implementation of hypnotic suggestions. This study compared the effects of hypnotic suggestion and imagery instruction for influencing the visuospatial and sensorimotor aspects of body-size representation. Both experimental manipulations produced significant increases (elongation) in both representations compared to baseline, although the effects were larger in the hypnotic suggestion condition. The effects of both manipulations were highly correlated across participants, suggesting overlapping mechanisms. Self-reports suggested that the use of voluntary imagery did not significantly contribute to the efficacy of either manipulation. Rather, top-down effects on body representations seem to be partly driven by response expectancies, spontaneous imagery, and hypnotic suggestibility in both conditions. These results are in line with current theories of suggestion and raise fundamental questions regarding the mechanisms driving the influence of cognition on body representations.


Subject(s)
Hypnosis , Humans , Hypnosis/methods , Suggestion , Imagery, Psychotherapy , Awareness , Cognition
13.
Cogn Emot ; 37(3): 397-411, 2023.
Article in English | MEDLINE | ID: mdl-36591900

ABSTRACT

Hypnosis is considered a unique tool capable of modulating cognitive processes. The extent to which hypnotic suggestions intervenes is still under debate. This study was designed to provide a new insight into this issue, by focusing on an unintentional emotional process: attentional bias. In Experiment 1, highly suggestible participants performed three sessions of an emotional Stroop task where hypnotic suggestions aiming to increase and decrease emotional reactivity towards emotional stimuli were administered within an intra-individual design. Compared to a baseline condition (without hypnotic suggestion), a significant increase in attentional bias was found when a hypnotic suggestion to increase emotional reactivity was administered. In contrast, the bias was eliminated when a suggestion to decrease emotional reactivity was administered. Experiment 2 investigated the effect of session repetition on attentional bias across three successive experimental sessions without hypnosis, and showed that the emotional Stroop effect did not vary across sessions. Hence, session repetition could not account for part of the modulation of attentional bias in Experiment 1. Taken together, the results suggest that specific hypnotic suggestions can influence elicitation of unintentional emotional processing. The implications are discussed regarding the locus of intervention of hypnotic suggestion in cognitive and emotional processes.


Subject(s)
Attentional Bias , Hypnosis , Humans , Stroop Test , Suggestion , Emotions
14.
Am J Clin Hypn ; 65(3): 186-210, 2023 Jan.
Article in English | MEDLINE | ID: mdl-36108171

ABSTRACT

Irving Kirsch is a leading figure in the field of psychological science who has advanced our understanding of hypnosis in key respects that have withstood the tests of time and replication. We honor his prodigious contributions over his distinguished career and extend his response expectancy theory in an integrative model that encompasses predictive coding. We review the construct of expectancies that he articulated and championed for decades and extended in response set theory. We propose novel hypotheses to align his innovative contributions with the most current findings in psychological science and to acknowledge the heuristic value of his work. We especially focus on (I) how the response set theory can be conceptualized in terms of the predictive coding model and (II) psycho-social constructs that need to be considered to better understand the effects of expectancies on hypnotic phenomena in an open and evidence-based integrative model of hypnosis.


Subject(s)
Hypnosis , Male , Humans , Suggestion
15.
Memory ; 30(9): 1205-1211, 2022 10.
Article in English | MEDLINE | ID: mdl-35670581

ABSTRACT

There is ample evidence to suggest that posing leading questions is dangerous, in that it may elicit compliant responses that are not necessarily accurate. Further, suggestive questioning is considered to possibly result in the development of false memories, implied in the suggestion. [Crombag, H. F. M., Wagenaar, W. A., & van Koppen, P. J. (1996). Crashing memories and the problem of 'source monitoring'. Applied Cognitive Psychology, 10(2), 95-104. https://doi.org/10.1002/(SICI)1099-0720(199604)10:2<95::AID-ACP366>3.0.CO;2-#] introduced a crashing memories paradigm in which participants are asked a single leading question about a non-existent film. The present research sought to replicate the false-memory-eliciting effect of the crashing memory induction. Further, we sought to explore associations with forensically relevant personality traits, particularly acquiescence, compliance, and suggestibility. In two studies, a significant minority of participants endorsed the leading question about the non-existent film (25.7%, and 38% respectively). We found no support for an association with acquiescence or compliance, but suggestibility was associated with the development of false memories.


Subject(s)
Individuality , Repression, Psychology , Humans , Memory , Mental Recall/physiology , Suggestion
16.
Neurosci Biobehav Rev ; 139: 104751, 2022 08.
Article in English | MEDLINE | ID: mdl-35760389

ABSTRACT

Elevated responsiveness to verbal suggestions is hypothesized to represent a predisposing factor for the dissociative disorders (DDs) and related conditions. However, the magnitude of this effect has not been estimated in these populations nor has the potential moderating influence of methodological limitations on effect size variability across studies. This study assessed whether patients with DDs, trauma- and stressor-related disorders (TSDs), and functional neurological disorder (FND) display elevated hypnotic suggestibility. A systematic literature search identified 20 datasets. A random-effects meta-analysis revealed that patients displayed greater hypnotic suggestibility than controls, Hedges's g = 0.92 [0.66, 1.18]. This effect was observed in all subgroups but was most pronounced in the DDs. Although there was some evidence for publication bias, a bias-corrected estimate of the group effect remained significant, g = 0.57 [0.30, 0.85]. Moderation analyses did not yield evidence for a link between effect sizes and methodological limitations. These results demonstrate that DDs and related conditions are characterized by elevated hypnotic suggestibility and have implications for the mechanisms, risk factors, and treatment of dissociative psychopathology.


Subject(s)
Hypnosis , Dissociative Disorders , Humans , Hypnosis/methods , Hypnotics and Sedatives , Suggestion
17.
J Forensic Sci ; 67(5): 2122-2129, 2022 Sep.
Article in English | MEDLINE | ID: mdl-35652501

ABSTRACT

We report on a unique Italian criminal case in which a court ruled that a therapist implanted false memories of abuse in a young girl. Using therapeutic excerpts, we show that the therapist used a multitude of problematic interventions that are all linked to false memory creation. Specifically, an analysis of the therapeutic excerpts showed that across many sessions, the therapist asked highly suggestive questions to the girl, implying that she was abused by her father. In addition, the girl underwent EMDR techniques that have been associated with memory undermining effects. Our analyses showed that although before treatment the girl did not have any recollection of being abused by her father, she gradually started to remember the abuse and identified the father as her abuser during the therapeutic sessions. Our case report clearly shows the danger of suggestive pressure in a therapeutic context causing patients to form false memories of abuse and supports the need to prevent the therapeutic practice of suggestive techniques.


Subject(s)
Criminals , Memory , Female , Humans , Mental Recall , Suggestion
18.
Zhongguo Zhong Yao Za Zhi ; 47(5): 1144-1152, 2022 Mar.
Article in Chinese | MEDLINE | ID: mdl-35343138

ABSTRACT

This study steps through the future perspectives and gives the development suggestions of Chinese medicinal materials(CMM) industry by presenting the characteristics and open problems during the 13 th Five-Year Plan period. The development of CMM industry presents the following trends:(1)the development of Dao-di herbs speeds up with the increasing demand for high-quality CMM;(2)the mismatch between supply and demand is aggravating, which presses for supply-side structural reform;(3)ecological planting will become the core mode of production and bolster rural revitalization;(4)the demand for CMM with both medical and edible values keeps growing, and the antibiotic-free feed policy brings significant opportunities;(5)the "Internet Plus CMM" wave emerges, which promotes the construction of traceability system. Finally, we put forward the following suggestions for the sustainable development of CMM industry:(1)optimizing the layout for the production of Dao-di herbs according to local conditions;(2)strengthening the commercialization of the seeds and the breeding, multiplication, and extension of CMM to accelerate the realization of specialized seed production, mechanized seed processing, localized variety layout, and county-based unified seed supply;(3)ensuring the safety of pesticide use and accelerating the registration of special pesticides;(4)promoting both theoretical and practical research on ecological production of CMM;(5)publicizing the demonstration and popularization of CMM traceability system. Overall, significant progress has been achieved in the CMM industry during the 13 th Five-Year Plan period, and this industry is in a critical stage of high-quality development, facing both challenges and opportunities.


Subject(s)
Drugs, Chinese Herbal , Medicine, Chinese Traditional , China , Drugs, Chinese Herbal/analysis , Industry , Plant Breeding
19.
Psychophysiology ; 59(7): e14015, 2022 07.
Article in English | MEDLINE | ID: mdl-35103984

ABSTRACT

Increased reward sensitivity has been proposed as an important transdiagnostic feature for a series of disorders, including addictive behaviors. Earlier studies suggest that a positive affective state characterized by the feeling of safety could reduce an individual's reward sensitivity. A promising technique to establish a feeling of safety on demand is to utilize post-hypnotic suggestions. We hypothesized that the feeling of safety elicited by post-hypnotic suggestions reduces neural signals of reward sensitivity. To test our predictions, we hypnotized 24 highly suggestible participants, suggested them to feel safe and coupled this feeling of safety to a post-hypnotic trigger that reactivates the feeling of safety outside the hypnotic state. Participants then played a risk game both in a safety condition using the post-hypnotic safety trigger and in a control condition using a neutral trigger. Simultaneously, we recorded their EEG. Participants reported significantly higher ratings of safety in the safety condition compared to the control condition. Even several weeks after the main experimental session, the post-hypnotic safety trigger still elicited a significantly stronger feeling of safety compared to the control condition. Moreover, the Reward Positivity (RewP) was significantly reduced in the safety condition. As the RewP amplitude has been proposed as a psychophysiological marker for reward sensitivity, we conclude that the suggestion of safety by post-hypnotic suggestions turns participants into a quiescence motivational state that makes them less reward sensitive. Therefore, we discuss implications of the post-hypnotic safety trigger for the treatment of disorders associated with increased reward sensitivity such as addictive behaviors.


Subject(s)
Electroencephalography , Hypnosis , Humans , Hypnosis/methods , Hypnotics and Sedatives , Reward , Suggestion
20.
Exp Dermatol ; 31(6): 878-889, 2022 06.
Article in English | MEDLINE | ID: mdl-35000228

ABSTRACT

Nocebo effects, that is, negative treatment outcomes due to negative expectancies, can increase itch. Moreover, indirect evidence has shown that nocebo hyperknesis can generalize to another itch modality. Knowledge on response generalization can help to prevent and decrease negative effects. The aims of this study were to investigate (1) the efficacy of inducing nocebo effects on cowhage-evoked itch via verbal suggestions and (2) whether these effects can generalize to (2a) mechanically evoked touch and (2b) mechanically evoked itch. Forty-four healthy participants watched a video suggesting that a nocebo solution increases cowhage-evoked itch and that a control solution does not affect itch. Subsequently, cowhage, mechanical itch, and mechanical touch stimuli were applied. Nocebo effects were measured as the difference in both mean and peak of the outcomes itch and urge to scratch between nocebo and control trials. Main analyses revealed significant nocebo effects on mean and peak itch for all stimuli. For urge to scratch, a significant nocebo effect was only observed for mechanical touch (peak). As mechanical stimuli did not induce pure sensations as planned, posthoc sensitivity analyses were run for mechanical stimuli that individually induced either touch or itch at baseline. These analyses showed similar results for generalization to mechanical itch, but generalization to mechanical touch was non-significant. This study showed that merely verbal suggestion can induce nocebo effects on cowhage-evoked itch and that these effects can generalize to another itch modality. Future studies may examine how to prevent negative experiences from generalizing to subsequent encounters.


Subject(s)
Nocebo Effect , Pruritus , Healthy Volunteers , Histamine , Humans , Pruritus/therapy , Suggestion , Treatment Outcome
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