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1.
Medicine (Baltimore) ; 99(44): e22871, 2020 Oct 30.
Article in English | MEDLINE | ID: mdl-33126334

ABSTRACT

BACKGROUND: Neck pain is a common complaint in the general population. Despite the consistent ongoing pain and the resulting economic burden on affected individuals, there have only been a few studies investigating the treatment of acute neck pain. This study aims to evaluate the effectiveness, safety, and cost-effectiveness of the motion style acupuncture treatment (MSAT) and acupuncture treatment for acute neck pain. METHODS: This 2-armed, parallel, multi-centered randomized controlled trial will be conducted at 4 community-based hospitals in Korea. A total of 128 subjects will be randomly assigned, at a 1:1 ratio, to the MSAT and the acupuncture treatment groups. Treatment will be administered 2 to 3 times a week for 2 weeks. The primary outcome will be the visual analog scale of neck pain on movement. The secondary outcomes will be the numeric rating scale of the neck, neck disability index, Northwick Park questionnaire, patient global impression of change, range of motion of the neck, 5-level EuroQol-5 dimension, 12-item Short-Form Health Survey, and EuroQol visual analogue scale. This protocol has been registered at the Clinicaltrials.gov (NCT04539184). DISCUSSION: To our knowledge, this study is the first well-designed multi-centered randomized controlled trial to evaluate the effectiveness, safety, and cost-effectiveness of MSAT on acute neck pain. The results of this study will be useful for clinicians in primary medical institutions that frequently treat acute neck pain patients and for policymakers working with national health insurance.


Subject(s)
Acupuncture Therapy/methods , Neck Pain/therapy , Pain Management/economics , Pain Management/standards , Treatment Outcome , Acupuncture Therapy/economics , Acupuncture Therapy/standards , Acute Pain/psychology , Acute Pain/therapy , Adult , Aged , Cost-Benefit Analysis , Female , Humans , Male , Middle Aged , Neck Pain/psychology , Pain Management/methods , Pain Measurement/methods , Republic of Korea , Surveys and Questionnaires
2.
Sci Rep ; 9(1): 16873, 2019 11 14.
Article in English | MEDLINE | ID: mdl-31727949

ABSTRACT

Pain is susceptible to various cognitive factors. Suppression of pain by hunger is well known, but the effect of food intake after fasting (i.e. refeeding) on pain remains unknown. In the present study, we examined whether inflammatory pain behavior is affected by 24 h fasting and 2 h refeeding. In formalin-induced acute inflammatory pain model, fasting suppressed pain behavior only in the second phase and the analgesic effect was also observed after refeeding. Furthermore, in Complete Freund's adjuvant-induced chronic inflammatory pain model, both fasting and refeeding reduced spontaneous pain response. Refeeding with non-calorie agar produced an analgesic effect. Besides, intraperitoneal (i.p.) administration of glucose after fasting, which mimics calorie recovery following refeeding, induced analgesic effect. Administration of opioid receptor antagonist (naloxone, i.p.) and cannabinoid receptor antagonist (SR 141716, i.p.) reversed fasting-induced analgesia, but did not affect refeeding-induced analgesia in acute inflammatory pain model. Taken together, our results show that refeeding produce analgesia in inflammatory pain condition, which is associated with eating behavior and calorie recovery effect.


Subject(s)
Acute Pain/diet therapy , Chronic Pain/diet therapy , Eating/psychology , Glucose/administration & dosage , Hyperalgesia/diet therapy , Pain Management/methods , Acute Pain/etiology , Acute Pain/physiopathology , Acute Pain/psychology , Analgesics, Opioid/pharmacology , Animals , Chronic Pain/etiology , Chronic Pain/physiopathology , Chronic Pain/psychology , Disease Models, Animal , Eating/physiology , Food Deprivation/physiology , Formaldehyde/administration & dosage , Freund's Adjuvant/administration & dosage , Hot Temperature/adverse effects , Hyperalgesia/etiology , Hyperalgesia/physiopathology , Hyperalgesia/psychology , Inflammation , Injections, Intraperitoneal , Male , Mice , Mice, Inbred C57BL , Naloxone/pharmacology , Narcotic Antagonists/pharmacology , Pain Measurement , Rimonabant/pharmacology
4.
Eur J Pain ; 23(4): 727-738, 2019 Apr.
Article in English | MEDLINE | ID: mdl-30421547

ABSTRACT

BACKGROUND: This study investigated whether the ability to disengage quickly from pain-related stimuli moderated the relative efficacy of a mindfulness-based intervention versus distraction in response to an experimental pain task. METHODS: Participants (n = 100) completed a dot probe task with eye tracking and were then randomized (2:2:1) to receive a mindfulness-based interoceptive exposure task (MIET), distraction instructions or no instructions (control group) before engaging in the cold pressor test. RESULTS: Participants who were allocated to the MIET condition reported a significantly higher pain threshold and distress than the distraction group, although not significantly higher than the control group. Those in the MIET group had improved tolerance compared to both the distraction and control groups. Difficulty disengaging from pain-related stimuli, as measured by the duration of the first fixation on sensory words, was found to moderate the relative efficacy of mindfulness versus distraction in terms of pain threshold and distress, but not tolerance. Those with difficulty disengaging from sensory pain words benefited less from the MIET. Duration of first fixation on sensory and affective pain words were highly correlated, and duration of first fixation on affective pain words also moderated the relative efficacy of MIET and distraction on threshold, but not distress. CONCLUSIONS: These results show that a single brief session of a mindfulness task was sufficient to change an acute pain experience in comparison with a distraction task, and that those who disengaged quickly from pain words benefited most. SIGNIFICANCE: This study demonstrated the efficacy of a novel, exposure-based mindfulness technique for pain tolerance and showed that those who disengaged easily from pain stimuli benefited most. This brief task could be clinically useful, particularly for those who are not overly focused on their pain symptoms.


Subject(s)
Acute Pain/therapy , Attentional Bias , Mindfulness/methods , Pain Threshold , Stress, Psychological , Acute Pain/psychology , Adolescent , Attention , Catastrophization , Cold Temperature , Eye Movement Measurements , Female , Humans , Male , Pain Measurement , Pain Perception , Young Adult
5.
Georgian Med News ; (283): 137-140, 2018 Oct.
Article in Russian | MEDLINE | ID: mdl-30516510

ABSTRACT

The aim of the investigation was to study the protective properties of the herbal preparation - biotrite and tranquilizer diazepam under the modeling of emotional and painful stress in rats. Materials and methods. The experiment was conducted on 24 white male rats of 5 months of age. Animals (6 rats in the group) were kept on the standard diet of the vivarium: 1st group was intact; rats of the 2nd, 3rd and 4th groups were reproduced acute painful emotional stress for 3 hours. 60 minutes before the stress, rats received per os: the 2nd group - water, the 3rd group - diazepam in a dose of 1.25 mg / kg body weight of rats; 4th group - a preparation of biotrite in a dose of 50 mg / kg. Results and conclusion. The conducted studies demonstrated significant adaptive properties of the biotrite preparation, and the degree of their manifestations was higher than the stress-protective effects of diazepam.


Subject(s)
Acute Pain/prevention & control , Anti-Anxiety Agents/therapeutic use , Plant Preparations/therapeutic use , Polyphenols/therapeutic use , Stress, Psychological/prevention & control , Acute Pain/blood , Acute Pain/pathology , Acute Pain/psychology , Animals , Anti-Anxiety Agents/isolation & purification , Diazepam/therapeutic use , Gastric Mucosa/drug effects , Gastric Mucosa/pathology , Leukocyte Count , Male , Monocytes/cytology , Neutrophils/cytology , Plant Leaves/chemistry , Plant Preparations/isolation & purification , Polyphenols/isolation & purification , Rats , Rats, Wistar , Stress, Psychological/blood , Stress, Psychological/pathology , Stress, Psychological/psychology , Triticum/chemistry
6.
Psychosom Med ; 80(9): 788-790, 2018.
Article in English | MEDLINE | ID: mdl-30395102

ABSTRACT

Chronic pain is a major problem in clinical medicine and public health, affecting approximately one in five adults, and is associated with significant societal and familial burden. Early-life adversities, psychological, and biobehavioral factors are associated with an elevated risk of the subsequent development of chronic pain. In this special issue of Psychosomatic Medicine, articles address the neuroscientific, psychological, and biobehavioral processes involved in acute and chronic pain. We focus on the following themes that emerged in this special issue: (a) risk factors and early adversity as related to chronic pain; (b) the role of expectations in shaping pain perception; and (c) mechanisms of interventions targeting pain modulation. This article concludes by outlining important new targets for research, including the neurobiology of pain, important methodological challenges, and targets for personalized pain interventions.


Subject(s)
Adverse Childhood Experiences , Chronic Pain , Pain Perception/physiology , Acute Pain/etiology , Acute Pain/physiopathology , Acute Pain/psychology , Chronic Pain/etiology , Chronic Pain/physiopathology , Chronic Pain/psychology , Humans , Neurosciences , Risk Factors
7.
Int J Rheum Dis ; 21(4): 796-803, 2018 Apr.
Article in English | MEDLINE | ID: mdl-27125577

ABSTRACT

AIM: To understand the patient experience of being admitted to hospital with acute low back pain (LBP), with a view to developing suggestions for care and LBP management guidelines. METHOD: Interpretive phenomenological analysis (IPA) was adopted to examine semi-structured interviews from patients admitted to hospital with acute LBP. Sampling continued until thematic saturation was reached (n = 14). Data were analyzed using the Framework Method, so that data from multiple participants could be systematically summarized, compared, and analyzed. RESULTS: Four themes were identified: pain and helplessness, desire for validation, interactions with healthcare teams, and a return to pre-morbid identity and roles. Patients' initial presentation to hospital was characterized by severe pain, disability and difficulty in communicating their illness experience. Patients expected doctors to investigate for an underlying cause of the back pain. To recover, they were required to navigate a system they did not understand, interacting with healthcare workers who seemed to operate independently rather than as a team. Patients viewed medical treatment as a means of returning to pre-morbid activities of daily living, roles and relationships. Using these themes, a model of the inpatient journey was developed. CONCLUSION: We have described new patient insights which highlight how the hospital environment adds unique challenges to managing acute LBP. Several suggestions for acute LBP management guidelines are made: developing lay summaries for patients, including methods for communicating the team structure and roles to patients, and ensuring all members of treating teams are educated to ensure guidelines are consistently implemented.


Subject(s)
Acute Pain/psychology , Delivery of Health Care, Integrated , Low Back Pain/psychology , Patient Admission , Patient Satisfaction , Acute Pain/diagnosis , Acute Pain/physiopathology , Acute Pain/therapy , Adaptation, Psychological , Adult , Aged , Aged, 80 and over , Attitude of Health Personnel , Communication , Cost of Illness , Female , Health Knowledge, Attitudes, Practice , Humans , Interviews as Topic , Low Back Pain/diagnosis , Low Back Pain/physiopathology , Low Back Pain/therapy , Male , Middle Aged , Pain Perception , Pain Threshold , Patient Care Team , Professional-Patient Relations , Qualitative Research , Recovery of Function , Severity of Illness Index
8.
J Gen Intern Med ; 32(10): 1106-1113, 2017 Oct.
Article in English | MEDLINE | ID: mdl-28702870

ABSTRACT

BACKGROUND: Medical management of acute pain among hospital inpatients may be enhanced by mind-body interventions. OBJECTIVE: We hypothesized that a single, scripted session of mindfulness training focused on acceptance of pain or hypnotic suggestion focused on changing pain sensations through imagery would significantly reduce acute pain intensity and unpleasantness compared to a psychoeducation pain coping control. We also hypothesized that mindfulness and suggestion would produce significant improvements in secondary outcomes including relaxation, pleasant body sensations, anxiety, and desire for opioids, compared to the control condition. METHODS: This three-arm, parallel-group randomized controlled trial conducted at a university-based hospital examined the acute effects of 15-min psychosocial interventions (mindfulness, hypnotic suggestion, psychoeducation) on adult inpatients reporting "intolerable pain" or "inadequate pain control." Participants (N = 244) were assigned to one of three intervention conditions: mindfulness (n = 86), suggestion (n = 73), or psychoeducation (n = 85). KEY RESULTS: Participants in the mind-body interventions reported significantly lower baseline-adjusted pain intensity post-intervention than those assigned to psychoeducation (p < 0.001, percentage pain reduction: mindfulness = 23%, suggestion = 29%, education = 9%), and lower baseline-adjusted pain unpleasantness (p < 0.001). Intervention conditions differed significantly with regard to relaxation (p < 0.001), pleasurable body sensations (p = 0.001), and desire for opioids (p = 0.015), but all three interventions were associated with a significant reduction in anxiety (p < 0.001). CONCLUSIONS: Brief, single-session mind-body interventions delivered by hospital social workers led to clinically significant improvements in pain and related outcomes, suggesting that such interventions may be useful adjuncts to medical pain management. TRIAL REGISTRATION: Trial Registry: ClinicalTrials.gov ; registration ID number: NCT02590029 URL: https://clinicaltrials.gov/ct2/show/NCT02590029.


Subject(s)
Acute Pain/psychology , Acute Pain/therapy , Hospitalization , Hypnosis/methods , Mindfulness/methods , Pain Management/methods , Acute Pain/diagnosis , Adult , Aged , Female , Hospitalization/trends , Humans , Male , Middle Aged , Pain Management/psychology , Pain Measurement/methods , Time Factors
9.
Cochrane Database Syst Rev ; 7: CD009984, 2017 07 12.
Article in English | MEDLINE | ID: mdl-28701028

ABSTRACT

BACKGROUND: This is an update of a Cochrane review previously published in 2014. Acute postoperative pain is one of the most disturbing complaints in open heart surgery, and is associated with a risk of negative consequences. Several trials investigated the effects of psychological interventions to reduce acute postoperative pain and improve the course of physical and psychological recovery of participants undergoing open heart surgery. OBJECTIVES: To compare the efficacy of psychological interventions as an adjunct to standard care versus standard care alone or standard care plus attention control in adults undergoing open heart surgery for pain, pain medication, psychological distress, mobility, and time to extubation. SEARCH METHODS: For this update, we searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, Web of Science, and PsycINFO for eligible studies up to February 2017. We used the 'related articles' and 'cited by' options of eligible studies to identify additional relevant studies. We checked lists of references of relevant articles and previous reviews. We searched the ProQuest Dissertations and Theses Full Text Database, ClinicalTrials and the WHO International Clinical Trials Registry Platform to identify any unpublished material or ongoing trials. We also contacted the authors of primary studies to identify any unpublished material. In addition, we wrote to all leading heart centres in Germany, Switzerland, and Austria to check whether they were aware of any ongoing trials. SELECTION CRITERIA: Randomised controlled trials comparing psychological interventions as an adjunct to standard care versus standard care alone or standard care plus attention in adults undergoing open heart surgery. DATA COLLECTION AND ANALYSIS: Two review authors (SZ and SK) independently assessed trials for eligibility, estimated the risk of bias and extracted all data. We calculated effect sizes for each comparison (Hedges' g) and meta-analysed data using a random-effects model. We assessed the evidence using GRADE and created 'Summary of findings' tables. MAIN RESULTS: We added six studies to this update. Overall, we included 23 studies (2669 participants).For the majority of outcomes (two-thirds), we could not perform a meta-analysis since outcomes were not measured, or data were provided by one trial only.No study reported data on the number of participants with pain intensity reduction of at least 50% from baseline. Only one study reported data on the number of participants below 30/100 mm on the Visual Analogue Scale (VAS) in pain intensity (very low-quality evidence). Psychological interventions did not reduce pain intensity in the short-term interval (g 0.39, 95% CI -0.18 to 0.96, 2 studies, 104 participants, low-quality evidence), medium-term interval (g -0.02, 95% CI -0.24 to 0.20, 4 studies, 413 participants, moderate-quality evidence) or in the long-term interval (g 0.05, 95% CI -0.20 to 0.30, 2 studies, 200 participants, moderate-quality evidence).No study reported data on median time to re-medication or on number of participants re-medicated. Only two studies provided data on postoperative analgesic use in the short-term interval, showing that psychological interventions did not reduce the use of analgesic medication (g 1.18, 95% CI -2.03 to 4.39, 2 studies, 104 participants, low-quality evidence). Studies revealed that psychological interventions reduced mental distress in the medium-term (g 0.37, 95% CI 0.13 to 0.60, 13 studies, 1388 participants, moderate-quality evidence) and likewise in the long-term interval (g 0.32, 95% CI 0.10 to 0.53, 14 studies, 1586 participants, moderate-quality evidence). Psychological interventions did not improve mobility in the medium-term interval (g 0.23, 95% CI -0.22 to 0.67, 3 studies, 444 participants, low-quality evidence), nor in the long-term interval (g 0.09, 95% CI -0.10 to 0.28, 4 studies, 458 participants, moderate-quality evidence). Only two studies reported data on time to extubation, indicating that psychological interventions reduced the time to extubation (g 0.56, 95% CI 0.08 to 1.03, 2 studies, 154 participants, low-quality evidence).Overall, the very low to moderate quality of the body of evidence on the efficacy of psychological interventions for acute pain after open heart surgery cannot be regarded as sufficient to draw robust conclusions.Most 'Risk of bias' assessments were low or unclear. We judged selection bias (random sequence generation) and attrition bias to be mostly low risk for included studies. However, we judged the risk of selection bias (allocation concealment), performance bias, detection bias and reporting bias to be mostly unclear. AUTHORS' CONCLUSIONS: In line with the conclusions of our previous review, there is a lack of evidence to support or refute psychological interventions in order to reduce postoperative pain in participants undergoing open heart surgery. We found moderate-quality evidence that psychological interventions reduced mental distress in participants undergoing open heart surgery. Given the small numbers of studies, it is not possible to draw robust conclusions on the efficacy of psychological interventions on outcomes such as analgesic use, mobility, and time to extubation respectively on adverse events or harms of psychological interventions.


Subject(s)
Acute Pain/therapy , Behavior Therapy/methods , Cardiac Surgical Procedures/adverse effects , Pain, Postoperative/therapy , Relaxation Therapy/methods , Acute Pain/psychology , Adult , Aged , Analgesics/therapeutic use , Cognitive Behavioral Therapy , Female , Humans , Male , Middle Aged , Pain Measurement , Pain, Postoperative/psychology , Randomized Controlled Trials as Topic , Stress, Psychological/epidemiology
10.
J Med Toxicol ; 13(3): 249-254, 2017 Sep.
Article in English | MEDLINE | ID: mdl-28646359

ABSTRACT

Epidemic increases in opioid use in the USA and globally highlight the need for effective adjunctive therapies to opioid-based analgesia. Given the shortcomings of behavioral adjuncts to opioid-based pain treatment, an urgent need exists for pain-related behavioral interventions that resonate with broad patient populations, can be delivered confidentially in any environment, and can incorporate new content automatically. Understanding the potential for automated behavioral therapies like music therapy in modulating the experience of pain may unlock methods to transition patients to lower doses of pharmacologic therapy or provide alternatives to opioids during acute exacerbations of pain. This manuscript describes the neurologic mechanism of action, theoretical basis, and potential applications of personalized music as a smartphone-based mHealth intervention for acute and chronic pain management.


Subject(s)
Acute Pain/prevention & control , Analgesics, Opioid/administration & dosage , Chronic Pain/prevention & control , Music Therapy/methods , Pain Management/methods , Telemedicine/methods , Acute Pain/diagnosis , Acute Pain/physiopathology , Acute Pain/psychology , Affect , Analgesics, Opioid/adverse effects , Chronic Pain/diagnosis , Chronic Pain/physiopathology , Chronic Pain/psychology , Combined Modality Therapy , Humans , Mobile Applications , Music Therapy/instrumentation , Opioid-Related Disorders/prevention & control , Pain Management/adverse effects , Pain Management/instrumentation , Pain Measurement , Pain Perception/drug effects , Pain Threshold/drug effects , Patient Care Team , Smartphone , Telemedicine/instrumentation , Treatment Outcome
11.
Trials ; 17: 189, 2016 Apr 06.
Article in English | MEDLINE | ID: mdl-27052991

ABSTRACT

BACKGROUND: To study the effect of Lanconone® (1000 mg) on acute pain on exertion as compared to the standard of care, Ibuprofen (400 mg). METHOD: The study recruited 72 subjects diagnosed with mild to moderate knee joint pain on exertion. Subjects with Pain Visual Analogue Scale of more than 40 mm were included. Uphill walking was provided as the stressor using Naughton's protocol on a treadmill. The subjects walked for 10 minutes continuously followed by a rest period and baseline pain score for index knee joint was recorded. Subjects were administered a single dose of Lanconone® (1000 mg)/Ibuprofen (400 mg). Thereafter the same stressor was provided at 0.5, 1, 2, 3, 4, and 6 hours, subsequently, pain scores were recorded on a visual analogue scale. Double stopwatch method was used to evaluate the onset of pain relief and time taken to meaningful pain relief. RESULT: Both Lanconone® and Ibuprofen showed the first perceived pain relief at 65.31 ± 35.57 mins as compared to 60.82 ± 32.56 mins respectively. The mean time taken to experience meaningful pain relief in Lanconone® group was 196.59 ± 70.85 mins compared to 167.13 ± 71.41 mins amongst Ibuprofen group. The meaningful pain relief continued for 6 hours. CONCLUSION: The current study successfully demonstrated rapid pain-relieving potential of Lanconone® which was comparable to Ibuprofen. No adverse event related to the interventions was reported in the study. TRIAL REGISTRATION: Clinical trials.gov NCT02417506 . 21 January 2015.


Subject(s)
Acute Pain/drug therapy , Analgesics/therapeutic use , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Arthralgia/drug therapy , Ibuprofen/therapeutic use , Knee Joint/drug effects , Pain Perception/drug effects , Plant Extracts/therapeutic use , Acute Pain/diagnosis , Acute Pain/physiopathology , Acute Pain/psychology , Adult , Analgesics/adverse effects , Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Arthralgia/diagnosis , Arthralgia/physiopathology , Arthralgia/psychology , Double-Blind Method , Exercise Test , Female , Humans , Ibuprofen/adverse effects , Knee Joint/physiopathology , Male , Middle Aged , Pain Measurement , Plant Extracts/adverse effects , Reaction Time , Severity of Illness Index , Time Factors , Treatment Outcome , United States , Walking
12.
Trials ; 16: 233, 2015 May 27.
Article in English | MEDLINE | ID: mdl-26013142

ABSTRACT

BACKGROUND: Neck pain is a common musculoskeletal condition with a point prevalence of around 15% in males and 23% in females that often presents in physiotherapy practice. Physical therapy and/or manipulation therapy is generally the first management option for patients with mechanical neck pain. Physical therapists treat mechanical neck pain with a number of interventions including joint mobilization and/or manipulation, therapeutic exercises or education. However, manipulation of the cervical spine carries some risks. Treating the thoracic spine for neck pain is an alternative approach. Emerging evidence suggests that it may be effective for treating neck pain without the risks associated with cervical spine manipulation. A new electromechanical device has recently been developed and tested for delivering multiple high velocity, low amplitude thrust manipulations to the spine. This device incorporates both auditory and visual systems that provide real time feedback on the applied treatment. The objective of this study is to compare the short- and long-term effects of manual versus mechanically assisted manipulations of the thoracic spine for neck pain patients. METHODS/DESIGN: A 6-month, randomized controlled trial consisting of 54 patients with acute or chronic neck pain patients will be conducted. Patients with no signs of major pathology and with little or no interference with daily activities will be recruited. Three treatment sessions with 4-day intervals will be carried out. The patients will be randomly assigned to receive either manually performed manipulations or electromechanical manipulations at the thoracic spine. The primary outcome is pain intensity as measured by the Visual Analogue Pain Rating Scale. The secondary outcome measures are neck physical disability using the Neck Disability Index, quality of life measured by the European Quality of Life 5 Dimensions 5 Levels and patients' improvement using the Patient's Global Impression of Change Scale. DISCUSSION: It is expected that both interventions will improve neck pain. This would be a significant finding, as thoracic spine manipulation for neck pain does not carry the same risk of injury as cervical spine manipulation. In addition, the results may provide useful information about therapeutic options for health care providers and patients for the problem of neck pain. TRIAL REGISTRATION: Current Controlled Trials ISRCTN88585962, registered January 2013.


Subject(s)
Acute Pain/therapy , Chronic Pain/therapy , Manipulation, Spinal/methods , Neck Pain/therapy , Thoracic Vertebrae/physiopathology , Acute Pain/diagnosis , Acute Pain/physiopathology , Acute Pain/psychology , Chronic Pain/diagnosis , Chronic Pain/physiopathology , Chronic Pain/psychology , Clinical Protocols , Disability Evaluation , Equipment Design , Humans , Manipulation, Spinal/adverse effects , Manipulation, Spinal/instrumentation , Neck Pain/diagnosis , Neck Pain/physiopathology , Neck Pain/psychology , Pain Measurement , Quality of Life , Recovery of Function , Research Design , Surveys and Questionnaires , Switzerland , Time Factors , Treatment Outcome
13.
J Health Psychol ; 20(3): 273-85, 2015 Mar.
Article in English | MEDLINE | ID: mdl-25762383

ABSTRACT

Drawing upon narrative data generated in a semi-structured interview with an 82-year-old female patient in geriatric physical rehabilitation, this clinical case study provides a detailed example of recognizing, assessing, and addressing spiritual distress as a symptom of physical pain. Data analysis focused on narrative content as well as on the interactive and performative aspects of narrating spiritual health issues in a close reading of two "attachment narratives." Results support the "narrative turn" in healthcare, including the therapeutic benefits of empathic listening as "narrative care" in geriatric rehabilitation and in healthcare in general.


Subject(s)
Narration , Physical Therapy Modalities/psychology , Spirituality , Acute Pain/psychology , Acute Pain/rehabilitation , Aged, 80 and over , Female , Humans , Interviews as Topic , Stress, Psychological/etiology , Stress, Psychological/psychology
14.
Cochrane Database Syst Rev ; (5): CD009984, 2014 May 26.
Article in English | MEDLINE | ID: mdl-24861376

ABSTRACT

BACKGROUND: Acute postoperative pain is one of the most disturbing complaints in open heart surgery, and is associated with a risk of negative consequences. Several trials investigated the effects of psychological interventions to reduce acute postoperative pain and improve the course of physical and psychological recovery of participants undergoing open heart surgery. OBJECTIVES: To compare the efficacy of psychological interventions as an adjunct to standard care versus standard care alone or standard care plus attention in adults undergoing open heart surgery on pain, pain medication, mental distress, mobility, and time to extubation. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2013, Issue 8), MEDLINE (1946 to September 2013), EMBASE (1980 to September 2013), Web of Science (all years to September 2013), and PsycINFO (all years to September 2013) for eligible studies. We used the 'related articles' and 'cited by' options of eligible studies to identify additional relevant studies. We also checked lists of references of relevant articles and previous reviews. We also searched the ProQuest Dissertations and Theses Full Text Database (all years to September 2013) and contacted the authors of primary studies to identify any unpublished material. SELECTION CRITERIA: Randomised controlled trials comparing psychological interventions as an adjunct to standard care versus standard care alone or standard care plus attention in adults undergoing open heart surgery. DATA COLLECTION AND ANALYSIS: Two review authors (SK and JR) independently assessed trials for eligibility, estimated the risk of bias and extracted all data. We calculated effect sizes for each comparison (Hedges' g) and meta-analysed data using a random-effects model. MAIN RESULTS: Nineteen trials were included (2164 participants).No study reported data on the number of participants with pain intensity reduction of at least 50% from baseline. Only one study reported data on the number of participants below 30/100 mm on the Visual Analogue Scale (VAS) in pain intensity. Psychological interventions have no beneficial effects in reducing pain intensity measured with continuous scales in the medium-term interval (g -0.02, 95% CI -0.24 to 0.20, 4 studies, 413 participants, moderate quality evidence) nor in the long-term interval (g 0.12, 95% CI -0.09 to 0.33, 3 studies, 280 participants, low quality evidence).No study reported data on median time to remedication or on number of participants remedicated. Only one study provided data on postoperative analgesic use. Studies reporting data on mental distress in the medium-term interval revealed a small beneficial effect of psychological interventions (g 0.36, 95% CI 0.10 to 0.62, 12 studies, 1144 participants, low quality evidence). Likewise, a small beneficial effect of psychological interventions on mental distress was obtained in the long-term interval (g 0.28, 95% CI 0.05 to 0.51, 11 studies, 1320 participants, low quality evidence). There were no beneficial effects of psychological interventions on mobility in the medium-term interval (g 0.23, 95% CI -0.22 to 0.67, 3 studies, 444 participants, low quality evidence) nor in the long-term interval (g 0.29, 95% CI -0.14 to 0.71, 4 studies, 423 participants, low quality evidence). Only one study reported data on time to extubation. AUTHORS' CONCLUSIONS: For the majority of outcomes (two-thirds) we could not perform a meta-analysis since outcomes were not measured, or data were provided by one trial only. Psychological interventions have no beneficial effects on reducing postoperative pain intensity or enhancing mobility. There is low quality evidence that psychological interventions reduce postoperative mental distress. Due to limitations in methodological quality, a small number of studies, and large heterogeneity, we rated the quality of the body of evidence as low. Future trials should measure crucial outcomes (e.g. number of participants with pain intensity reduction of at least 50% from baseline) and should focus to enhance the quality of the body of evidence in general. Altogether, the current evidence does not clearly support the use of psychological interventions to reduce pain in participants undergoing open heart surgery.


Subject(s)
Acute Pain/therapy , Behavior Therapy/methods , Cardiac Surgical Procedures/adverse effects , Pain, Postoperative/therapy , Relaxation Therapy/methods , Acute Pain/psychology , Adult , Aged , Cognitive Behavioral Therapy , Female , Humans , Male , Middle Aged , Pain Measurement , Pain, Postoperative/psychology , Randomized Controlled Trials as Topic
15.
Pain Manag Nurs ; 15(1): 59-68, 2014 Mar.
Article in English | MEDLINE | ID: mdl-24602425

ABSTRACT

The purpose of this study was to investigate the effect of transcutaneous electrical nerve stimulation (TENS) for pain relief during extracorporeal shock-wave lithotripsy (ESWL) procedure. An experimental study with repeated measures design was used in this study. Fifty patients aged 20-65 years receiving ESWL treatment were used for this convenience sample. Two applications were used for each patient: one involving administration of TENS instrument for ESWL treatment and the other without TENS. For effective stimulation, 2 stimulator electrodes were placed paravertebrally at L1 and 2 near the lithotripter shock tube before ESWL. Blood pressure, heart rate, pain intensity, analgesic use, and side effects were measured every 10 minutes during the procedure and after the end of ESWL. Results showed that TENS application decreased patients' intensity of pain and amount of analgesic requests and, related to that, decreased the incidence of side effects and increased patients' satisfaction during ESWL. TENS application is recommended as a pain-relieving technique during ESWL.


Subject(s)
Acute Pain/nursing , Acute Pain/therapy , Lithotripsy/adverse effects , Lithotripsy/nursing , Nephrology Nursing/methods , Transcutaneous Electric Nerve Stimulation/methods , Acute Pain/psychology , Adult , Aged , Anxiety/nursing , Anxiety/psychology , Female , Humans , Male , Middle Aged , Pain Management/methods , Pain Management/nursing , Pain Measurement , Treatment Outcome , Young Adult
16.
Am Psychol ; 69(2): 188-96, 2014.
Article in English | MEDLINE | ID: mdl-24547804

ABSTRACT

This article provides an illustrative overview of neurophysiological changes related to acute and chronic pain involving structural and functional brain changes, which might be the targets of psychological interventions. A number of psychological pain treatments have been examined with respect to their effects on brain activity, ranging from cognitive- and operant behavioral interventions, meditation and hypnosis, to neuro- and biofeedback, discrimination training, imagery and mirror treatment, as well as virtual reality and placebo applications. These treatments affect both ascending and descending aspects of pain processing and act through brain mechanisms that involve sensorimotor areas as well as those involved in affective-motivational and cognitive-evaluative aspects. The analysis of neurophysiological changes related to effective psychological pain treatment can help to identify subgroups of patients with chronic pain who might profit from different interventions, can aid in predicting treatment outcome, and can assist in identifying responders and nonresponders, thus enhancing the efficacy and efficiency of psychological interventions. Moreover, new treatment targets can be developed and tested. Finally, the use of neurophysiological measures can also aid in motivating patients to participate in psychological interventions and can increase their acceptance in clinical practice.


Subject(s)
Acute Pain/physiopathology , Brain/physiopathology , Chronic Pain/physiopathology , Acute Pain/psychology , Acute Pain/therapy , Biofeedback, Psychology , Chronic Pain/psychology , Chronic Pain/therapy , Cognitive Behavioral Therapy , Discrimination Learning , Functional Neuroimaging , Humans , Imagery, Psychotherapy , Magnetic Resonance Imaging , Meditation , Neurofeedback
17.
Pain Manag Nurs ; 14(4): e196-e203, 2013 Dec.
Article in English | MEDLINE | ID: mdl-24315273

ABSTRACT

There are adverse physiologic effects of pain in neonates, and effective pain management must be an essential aspect of neonatal care. In this study we assessed the effect of a nonmaternal familiar scent on the neonatal pain responses. This study included 135 neonates randomly assigned to one of three groups. During arterial puncture, one group was exposed to a vanillin scent on a gauze pad held next to their nose. They were familiarized with it the night before blood sampling by a scented gauze pad placed in the incubator next to their head for an average duration of 8.65 hours. The second group was not familiarized with the scent but was exposed to it during the procedure. The third group was neither familiarized nor exposed to the scent. The duration of crying in the familiar scent group was significantly lower than in the two other groups. Comparison of the physiologic parameters showed less variation in oxygen saturation level during arterial puncture in the familiar scent group. In this study, a familiar scent could reduce crying and oxygen consumption during arterial puncture.


Subject(s)
Acute Pain/psychology , Acute Pain/therapy , Aromatherapy/methods , Pain Management/methods , Smell , Acute Pain/nursing , Aromatherapy/nursing , Benzaldehydes , Crying/psychology , Female , Humans , Infant Behavior/psychology , Infant, Newborn , Jaundice/nursing , Jaundice/psychology , Male , Odorants , Pain Management/nursing , Phlebotomy/adverse effects , Punctures/adverse effects , Punctures/psychology
18.
Am J Clin Hypn ; 55(4): 325-42, 2013 Apr.
Article in English | MEDLINE | ID: mdl-23724568

ABSTRACT

This article details a self-hypnosis technique designed to teach patients how to manage acute or chronic pain through directed focus. The focused suggestion with somatic anchoring technique has been used with various types of pain, including somatic pain (arthritis, post-injury pain from bone breaks, or muscle tears), visceral pain (related to irritable bowel disease), and neuropathic pain (related to multiple sclerosis). This technique combines cognitive restructuring and mindfulness meditation with indirect and direct suggestions during hypnosis. The case examples demonstrate how the focused suggestion with somatic anchoring technique is used with both acute and chronic pain conditions when use of long-term medication has been relatively ineffective.


Subject(s)
Hypnosis/methods , Meditation/methods , Pain Management/methods , Pain/psychology , Acute Pain/psychology , Acute Pain/therapy , Adult , Chronic Pain/psychology , Chronic Pain/therapy , Female , Humans , Meditation/psychology , Middle Aged , Pain Management/psychology , Suggestion
19.
Klin Padiatr ; 225(3): 110-4, 2013 May.
Article in English | MEDLINE | ID: mdl-23709132

ABSTRACT

OBJECTIVES: Blood drawings are very painful and stressful for children. In a prospective control group study we investigated if using a picture book could reduce the children's pain expectation. In addition, the children's pain experience and the observed pain behaviour was monitored. PATIENTS/METHODS: Block-randomization were used and 120 children at the age of 6-12 years who were visiting the general pediatric and coagulation outpatient clinics were included in this study. Pain expectation and experience were assessed with the Face-Pain-Scale-Revised and the pain behavior with the Faces-Legs-Activity-Cry-Consolability Scale. Multivariate covariance analysis was used for data analysis. RESULTS: The results showed that with statistical controlling the influence of the primary pain expectation (baseline) the pain expectation before blood withdrawal was reduced significantly (p=0.001) and effectively (ES=0.56) using the picture book. Children who received no local anaesthesia reported that they felt less pain during blood drawing after reading the picture book. The few children with local anaesthesia reported no benefit from the picture book. The observed use of local anaesthesia was very heterogeneous. CONCLUSIONS: The results recommend the usage of this picture book in everyday practice, if the use of local anaesthesia could not be used in an appropriate way.


Subject(s)
Acute Pain/prevention & control , Acute Pain/psychology , Bibliotherapy/methods , Blood Specimen Collection/psychology , Set, Psychology , Anesthesia, Local , Child , Female , Germany , Humans , Male , Outpatient Clinics, Hospital , Pain Measurement/methods , Prospective Studies
20.
Eur J Pain ; 17(5): 742-52, 2013 May.
Article in English | MEDLINE | ID: mdl-23169690

ABSTRACT

BACKGROUND: This study aimed to investigate the efficacy of mindfulness training in comparison with relaxation training on pain, threshold and tolerance during the cold pressor task. METHODS: Undergraduate psychology students (n = 140) were randomly assigned to receive reassuring or threatening information about the cold pressor. Participants were then re-randomized to receive mindfulness or a control intervention: relaxation training. RESULTS: Analyses confirmed that the threat manipulation was effective in increasing worry, fear of harm and expectations of pain, and reducing coping efficacy. Interaction effects revealed that mindfulness was effective in increasing curiosity and reducing decentring under conditions of high threat but not low threat. Other interactions on cognitive variables (attentional bias to pain and self-focus) confirmed that mindfulness and relaxation appeared to exert influences under different conditions (i.e. mindfulness: high threat; and relaxation: low threat). Despite these cognitive effects being discerned under different conditions, there were no differences between mindfulness and relaxation on pain, tolerance or threshold in either threat group. CONCLUSIONS: These results show that a single, brief session of mindfulness based on body scanning is not sufficient to change the way in which individuals approach an experimental pain task in comparison with relaxation, which has previously been shown to be ineffective.


Subject(s)
Acute Pain/psychology , Pain Threshold/psychology , Relaxation/psychology , Acute Pain/physiopathology , Adolescent , Adult , Anxiety/psychology , Attention/physiology , Female , Humans , Male , Pain Measurement , Young Adult
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