1.
Ann Noninvasive Electrocardiol
; 23(5): e12535, 2018 09.
Article
in English
| MEDLINE
| ID: mdl-29488680
ABSTRACT
Yew leaves poisoning is a rare life-threatening intoxication, whose diagnosis can be difficult. Initial symptoms are nausea, vomiting, abdominal pain, dizziness, tachycardia, muscle weakness, confusion, beginning within 1 hr from ingestion and followed by bradycardia, ventricular arrhythmias, ventricular fibrillation, severe hypotension, and death. Taxine-derived alkaloids are responsible for the toxicity of the yew leaves, blocking sodium and calcium channels, and causing conduction abnormalities. Because of lack of a specific antidote and limited efficacy of common antiarrhythmic drugs, prompt diagnosis, detoxification measures, and immediate hemodynamic support (also with transvenous cardiac stimulation) are essential.
Subject(s)
Arrhythmias, Cardiac/chemically induced , Cephalotaxus/poisoning , Electrocardiography/methods , Heart Arrest/chemically induced , Plant Extracts/poisoning , Plant Leaves/poisoning , Adrenergic alpha-Agonists/therapeutic use , Adult , Aged , Amiodarone/therapeutic use , Anti-Arrhythmia Agents/therapeutic use , Arrhythmias, Cardiac/therapy , Cardiopulmonary Resuscitation , Charcoal/therapeutic use , Female , Gastric Lavage , Heart Arrest/therapy , Humans , Magnesium Sulfate/therapeutic use , Male , Middle Aged , Norepinephrine/therapeutic use , Pacemaker, Artificial , Sodium Bicarbonate/therapeutic use , Treatment Outcome
2.
Farm. hosp
; 41(5): 640-641, sept.-oct. 2017.
Article
in Spanish
| IBECS
| ID: ibc-166603
ABSTRACT
No disponible