William Burroughs: Sailor of the Soul.

In 1953, William Seward Burroughs made several important and largely unrecognized discoveries relating to the composition and clinical pharmacological effects of the hallucinogenic plant potion known as yagé or ayahuasca. Illustrations of Burroughs' voucher sample of Psychotria viridis and his letter to the father of modern ethnobotany, Richard Evans Schultes, are published here for the very first time.

[Protestant clergymen among Hahnemann's clientele. Patient histories in letters]. / Evangelische Geistliche in Hahnemanns Patientenschaft. Krankengeschichten in Briefen.

As part of the research project, developments in the history of science and in the regional and ecclesiastic history of the late feudal petty state of Köthen-Anhalt have been assessed and numerous documents of the Nagel and Mühlenbein family histories examined that place the transcribed patient letters of the two Protestant clergymen within the context of the Hahnemann Archives. These findings complement and extend previous insights into Hahnemann's Köthen clientele, especially when it comes to the structure and milieu of the local clerical elite. Inspired by the interpretive methods of sequential textual analysis, form and content of the letters of the two clergymen and their relatives were also investigated as methodically structured lines of communication. The body of sources published here presents--embedded in the body-image (of sickness and health) prevalent at the time--the medical cultures of educated patients as well as the increasingly professionalized medical practices of Samuel Hahnemann in a flourishing urban doctor's surgery. The correspondence between the pastors Albert Wilhelm Gotthilf Nagel (1796-1835) and August Carl Ludwig Georg Mühlenbein (1797-1866), presented here in a standard edition, has been investigated at Fulda University as part of the project 'Homöopathisches Medicinieren zwischen alltäglicher Lebensführung und professioneller Praxis' ('Homeopathic medicine between everyday use and professional practice'). Of the altogether 78 transcribed documents, 53 are letters written by either of the two pastors, 16 are patient journals by Samuel Hahnemann, 9 letters by the pastors' wives and Mühlenbein's mother. The two series of letters, originally composed between 1831 and 1833 in old German cursive script, can now be used as sources for research into the history of homeopathy.

Lady Brilliana Harley (1598-1643): Her medicines and her doctors.

Lady Brilliana Harley was the redoubtable chatelaine of Brampton Bryan Castle in Herefordshire during the mid-seventeenth century. Her many letters reveal much about the medications which she dispensed to her family and about the family's medical attendants. Whenever possible the Harleys preferred to consult university-educated physicians rather than the local apothecary or surgeon. These physicians are all known from other sources but Brilliana's letters add to what is known of their provincial practices. In particular, they reveal their willingness to undertake blood-letting, often thought to be the province of the more lowly surgeon, and they emphasise the great distances travelled by these practitioners and the difficulties faced by two of them during the Civil War.

[Analysis of Peng Zemin's medical letter].

Mr. Peng Zemin, a senior leader of the Kuomintang leftist and patriotic overseas Chinese, had acknowledged the famous Guangdong modern TCM masters Chen Botan as his mentor in TCM for six years, and deeply affected by Chen Botan's way of prescribing large dose of classical recipes. Guang-dong Chinese Medicine Museum has collected a number of Mr. Peng Zernin' s letters, which were handwriting works written by Mr. Peng Zemin himself to his nephew Peng Bingtang who worked in the government of Guyang Wulanchabu League, Inner Mongolia. Among them, nine are related to medicine, reflecting Mr. Peng Zemin' s medical activities, medical ethics and medical practice experience, the way he prescribed after Chen Botan's characteristics of prescribing and applying materia medica.

Huygens' headache.

BACKGROUND: Christiaan Huygens (1629-1695) was a Dutch mathematician, physicist, and astronomer. He became well-known as inventor of the pendulum clock and described light as a wave phenomenon. He became Fellow of the Royal Society (London) and member of the Académie des Sciences (Paris). From the correspondence with family members and famous scientists, we learn that he suffered from frequent headaches. AIM: To study Huygens' 22-volume Oeuvres Complètes (1888-1950) to find letters in which his headaches are mentioned and translate pertinent sections into English. CONCLUSIONS: Although a posthumous diagnosis of Huygens' headaches is somewhat hazardous, the recurrent episodes with incapacitating headache and family history over two generations are suggestive for migraine. It becomes clear that it impeded his writing, reading, and research. From the letters we get an impression of the impact of the headache upon his life and the treatments that were applied in the 17th century.

Leadership lessons in global nursing and health from the Nightingale Letter Collection at the University of Alabama at Birmingham.

This article analyzes the components of Florence Nightingale's visionary leadership for global health and nursing within the historical context of Great Britain's colonization of India. The descriptive study used the qualitative approach of narrative analysis to analyze selected letters in the Nightingale Letter Collection at the University of Alabama at Birmingham that Nightingale wrote to or about Dr. Thomas Gillham Hewlett, a physician and health officer in Bombay, India. The authors sought to increase understanding of Nightingale's visionary leadership for global nursing and health through a study of the form and content of the letters analyzed as temporally contextualized data, focusing on how the narratives are composed and what is conveyed. Several recurring themes central to Nightingale's leadership on global nursing and health emerge throughout these letters, including health and sanitation reform, collaborative partnerships, data-driven policy development, and advocacy for public health. These themes are illustrated through her letters to and testimony about Dr. Thomas Gillham Hewlett in her vivid descriptions of health education and promotion, data-driven policy documents, public health and sanitation advice, and collaboration with citizens, medicine, policy makers, and governments to improve the health and welfare of the people of India. The focus on leadership in nursing as a global construct highlights the lessons learned from University of Alabama at Birmingham's Nightingale Letter Collection that has relevance for the future of nursing and health care, particularly Nightingale's collaboration with policy leaders, her analysis of data to set policy agendas, and public health reform centered on improving the health and well-being of underserved populations.

[Augustin Delondre and Friedrich AuguIst Flückiger : an unpublished correspondence 1868-1869]. / Augustin Delondre et Friedrich August Flückiger : une correspondance inédite 1868-1869.

This article describes an unpublished correspondence between Augustin-Ambroise Delondre (1823- 1879), son of the famous pharmacist Augustin - Pierre Delondre and Friedrich August Flückiger, Swiss pharmacist (1828-1894), professor between 1873 to 1892 of the Chair in pharmacy at the university of Strasbourg and considered as the father of pharmacognosy. This set of 9 unique hand- written letters (1868 and 1869) allows to have an clearer idea of their scientific and human relations.

Breve histórico dos cursos de Rudolf Steiner aos estudantes de medicina e jovens médicos / Brief history of Rudolf Steiner's courses to medical students and young doctors

O autor, baseado em comunicação pessoal com Madeleine van Deventer e em obras publicadas de Rudolf Steiner e Peter Selg, faz um relato dos preparativos e fatos que antecederam os primeiros cursos de antroposofia voltados aos jovens médicos e estudantes de medicina, na década de 1920. Destaca-se a figura de Helene von Grunelius, fundamental para a mobilização e entusiasmo daqueles que ouviriam de Steiner as bases para a humanização da medicina, fundamentada na antroposofia.(AU)

The author, based on personal communication from Madeleine van Deventer and from published lectures of Rudolf Steiner and Peter Selg, reports the preparations and events before the first courses of anthroposophy to young doctors and medical students in the 1920s. Helene von Grunelius was highlighted. She was fundamental for the mobilization and enthusiasm of those who would hear Steiner foundations for the humanization of medicine, based on anthroposophy.(AU)

Medical men, women of letters, and treatments for eighteenth-century hysteria.

This paper explores evolving treatments for hysteria in the eighteenth century by examining a selection of works by both physician-writers and educated literary women. The treatments I identify--which range from aggressive bloodlettings, diets, and beatings, to exercise, fresh air, and writing cures--reveal a unique culture of therapy in which female sufferers and doctors exert an influence on one another's notions of what constitutes appropriate management of women's mental illness. A scrutiny of this exchange of ideas suggests that female patients were not simply oppressed and silenced by male practitioners; rather, their collective voice, intellect, and expertise helped to form progressive treatments for eighteenth-century hysteria.

An extraordinary testimonial of thermal rehabilitation: Giuseppe Garibaldi - 2011: 150th Anniversary of the Italian Unification.

On the occasion of the 150th Anniversary of the Italian Unification, the discovery of some letters by Giuseppe Garibaldi - referring to a period of thermal treatments at the Baths in Civitavecchia (Rome) - gave us the opportunity for writing a commentary about a not well known experience in the Two World Hero's life: the numerous treatments carried out at many Italian spa centres for treating a rheumatic pathology (probably a rheumatoid polyarthritis) and the outcomes of various war wounds, especially the famous gunshot-wound in his right ankle during the Battle of Aspromonte, in 1862.

The concept of health - in the history of medicine and in the writings of Hahnemann.

The number of notions of health is not infinite. In the history of medicine we can only find a number of different conceptions or paradigmatic ideas of health, in a variety of references and combinations. Health was seen as: 1. harmonious balance between principles or entities, 2. result of a struggle against opposing forces, 3. continuous dialectical process, 4. hierarchy of components or functions, 5. potential to perform and to develop, 6. transcendence towards higher levels of being, 7. result of conscious autonomous action, 8. optimal causal functioning, or 9. public task and responsibility. Hahnemann's view of health, as reflected in his writings, utilized virtually all of these elements. They reappear for instance as: 1. harmonious tuning of the life force, 2. defeat of pathogenetic influences, 3. admittance of aggravations, 4. autocracy of the spirit-like life principle, 5. reference to a higher goal of human existence, 6. perfecting character of medical service, 7. concern about dietetics and life style, 8. utilization of causality and natural science, and 9. appealing to governmental provisions and medical police. These paradigms have been repeatedly recombined and applied. The theory of medicine is the attempt to analyze, adjust, and develop concepts that meet the demand of contemporary medical practice. Medical theory lies between the fields of observable facts and metaphysical convictions. Distinguishing the levels of practice, theory, and metaphysics could allow the open discussion of theoretical issues, such as the concept of health or disease, without raising purely theoretical objections to well-established practice.

["And thus there was another pointless thing in the country [...]". The failed homoeopathic training of missionaries at the Basle Mission]. / "[...] und war ein Stück Grümpel mehr im Lande". Die gescheiterten Versuche einer homöopathischen Aus- bildung für Missionare der Basler Mission.

This article deals with the unsuccessful attempts to allow missionaries of the Basle Mission to undergo homoeopathic training. Before the Mission undertook systematic medical missionary work in society in the 1880s, there were various requests and suggestions to train the missionaries in homoeopathy. Here, these attempts are put into a greater context of the research into "Homoeopathy and Mission". It becomes clear that Hahnemann's teachings were certainly used in the Mission, even if finding this out is sometimes arduous.

[Samuel Hahnemann: physician and adviser to the Princess Luise of Prussia from 1829 to 1835]. / Samuel Hahnemann: Arzt und Berater der Prinzessin Luise von Preussen in den Jahren 1829 bis 1835.

The nearly 500 pages of letters (edited and commented in a medical dissertation by the author), written by a Prussian Princess in the 19th century to Dr. Samuel Hahnemann, the founder of homoeopathy, provide a fairly complete patient history thanks to the homoeopathic method which obliges patients to observe and describe the complaints and the changes they experience during treatment. The achievements of Hahnemann's therapy were so remarkable that the patient engaged his disciple Dr.Julius Aegidi as her court physician during the years 1831 to 1834. In no other of Hahnemann's published case histories so many dreams are described. The diagnosis within the historical context could be hysteria, hypochondria and melancholy. The therapy consisted in the prescription of homoeopathic remedies but also, among other prescriptions, in taking placebos, application of mesmerism, diet and life style advice. Hahnemann was opposed to vaccination. The doctor-patient-relationship became very intense. It can be said that Hahnemann acted as a psychotherapist. As the Princess rather liked speaking about her complaints her compliance in describing symptoms was excellent. It was less so in taking verum, applying mesmerism and changing her lifestyle. The success of the treatment was limited by the Princess's court and family circumstances and probably by Hahnemann's restriction to psora theory and C30 potencies. The dissertation is the most extensive patient history from Hahnemann's medical practice ever published.

Correspondence of Charles Darwin on James Torbitt's project to breed blight-resistance potatoes.

The most prolific of Darwin's correspondents from Ireland was James Torbitt, an enterprising grocer and wine merchant of 58 North Street, Belfast. Between February 1876 and March 1882, 141 letters were exchanged on the feasibility and ways of supporting one of Torbitt's commercial projects, the large-scale production and distribution of true potato seeds (Solan um tuberosum) to produce plants resistant to the late blight fungus Phytophthora infestans, the cause of repeated potato crop failures and thus the Irish famines in the nineteenth century. Ninety-three of these letters were exchanged between Torbitt and Darwin, and 48 between Darwin and third parties, seeking or offering help and advice on the project. Torbitt's project required selecting the small proportion of plants in an infested field that survived the infection, and using those as parents to produce seeds. This was a direct application of Darwin's principle of selection. Darwin cautiously lobbied high-ranking civil servants in London to obtain government funding for the project, and also provided his own personal financial support to Torbit.