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1.
Kyobu Geka ; 76(8): 633-637, 2023 Aug.
Article in Japanese | MEDLINE | ID: mdl-37500552

ABSTRACT

An 89-year-old man who had undergone aortic valve replacement with a 21 mm Mosaic bioprosthetic valve at another hospital 14 years ago was admitted to the emergency room for a sudden respiratory distress two days prior and was diagnosed with severe aortic regurgitation( AR) caused by valve insufficiency and acute heart failure secondary to low cardiac function. Upon admission, he was found to have severe hypoxia with PaO2 of 40 mmHg range, and transcatheter aortic valve replacement (TAVI, TAV in SAV) with a 20 mm SAPIEN3 was performed under local anesthesia for fear of hypotension while under general anesthesia. After confirming that AR had completely disappeared, the patient was intubated and discharged from the operating room on a mechanical ventilator. The patient was weaned from the ventilator on the second postoperative day and was transferred to the other hospital for rehabilitation, 48 days postoperatively. Although there is no report on the comparative study of anesthesia methods for emergency transcatheter aortic valve implantation( TAVI), TAVI under regional anesthesia is minimally invasive with a lower risk for hypotension than general anesthesia. Therefore, we believe it is useful for patients with acute heart failure and hypotension. In addition, it is important to use a balloon expandable valve with excellent implantability to complete the procedure in a short time.


Subject(s)
Aortic Valve Stenosis , Heart Failure , Heart Valve Prosthesis Implantation , Heart Valve Prosthesis , Hypotension , Transcatheter Aortic Valve Replacement , Male , Humans , Aged, 80 and over , Aortic Valve/surgery , Transcatheter Aortic Valve Replacement/methods , Anesthesia, Local , Aortic Valve Stenosis/surgery , Treatment Outcome , Heart Valve Prosthesis Implantation/methods , Hypotension/etiology , Hypotension/surgery , Heart Failure/etiology , Heart Failure/surgery
2.
ScientificWorldJournal ; 2013: 709059, 2013.
Article in English | MEDLINE | ID: mdl-24228013

ABSTRACT

In this retrospective cohort study, we aimed to determine the incidence of intraoperative maternal hypotension during fetoscopic surgery for twin-twin transfusion syndrome (TTTS) and to evaluate the impact of intraoperative hypotension on fetal survival. A total of 328 TTTS patients with recipient twin cardiomyopathy who underwent fetoscopic surgery under epidural anesthesia were included. The exposure of interest was maternal medical therapy with nifedipine for the treatment of fetal cardiomyopathy. We found that intraoperative hypotension occurred in 53.4% (175/328 patients). There was no statistically significant difference in incidence of hypotension between nifedipine exposure and nonexposure groups (54.8% versus 50.8%, P = 0.479). However, the nifedipine exposure group received a statistically significant higher dose of phenylephrine (7.04 ± 6.38 mcg/kg versus 4.70 ± 4.14 mcg/kg, P = 0.018) and higher doses of other vasopressor, as counted by number of treatments (6.06 ± 4.58 versus 4.96 ± 3.42, P = 0.022). There were no statistically significant differences in acute fetal survival rate (within 5 days) and fetal survival rate at birth between hypotensive and nonhypotensive patients. We concluded that preoperative exposure to nifedipine resulted in increased intraoperative maternal vasopressor requirement during fetoscopic surgery under epidural anesthesia. In patients who had intraoperative maternal hypotension, there was no correlation between the presence of maternal hypotension and postoperative fetal survival.


Subject(s)
Fetofetal Transfusion/mortality , Fetofetal Transfusion/surgery , Fetoscopy/mortality , Hypotension/mortality , Hypotension/prevention & control , Nifedipine/therapeutic use , Pregnancy Complications, Cardiovascular/mortality , Adult , Cohort Studies , Female , Fetal Death/epidemiology , Fetofetal Transfusion/pathology , Humans , Hypotension/surgery , Incidence , Ohio/epidemiology , Pregnancy , Pregnancy Complications, Cardiovascular/surgery , Retrospective Studies , Risk Factors , Survival Rate , Treatment Outcome , Vasodilator Agents/administration & dosage
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