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2.
J Vet Intern Med ; 33(5): 2057-2066, 2019 Sep.
Article in English | MEDLINE | ID: mdl-31490022

ABSTRACT

BACKGROUND: Gallbladder mucoceles (GBM) typically are treated by cholecystectomy. Medical management rarely has been reported and medical and surgical management have not been compared. HYPOTHESIS/OBJECTIVES: To compare survival of dogs treated for GBM by medical management or cholecystectomy or both. ANIMALS: Eighty-nine client-owned dogs diagnosed with GBM that received cholecystectomy or medical treatment or both from 2011 to 2017. METHODS: Potential cases were identified by searching the medical records database. Data collected included signalment, clinicopathologic results, treatments, and ultrasonographic images and reports. Dogs were grouped according to the treatment received (medical management, surgical treatment, or both) that was chosen at the discretion of the attending veterinarian. Survival analysis was performed and prognostic variables identified and compared between treatment groups. RESULTS: Of dogs surviving at least 14 days after diagnosis, median survival times were 1802 (95% confidence interval [CI], 855-not reached) days, 1340 (95% CI, 444-1340) days, and 203 (95% CI, 18-525) days, for the surgical, medical, and medical then surgical treatment groups, respectively, and differed significantly (P < .0001). Gallbladder mucocele type (P = .05), serum alkaline phosphatase activity (P = .0001), and serum creatinine (P = .002) and phosphorus (P = .04) concentrations were associated with decreased survival across groups. Suspicion of biliary rupture on abdominal ultrasound (AUS) examination was correlated with increased survival in the surgical group (P = .02). CONCLUSIONS AND CLINICAL IMPORTANCE: Cholecystectomy for the treatment of GBM results in the best long-term survival in dogs surviving the immediate postoperative period (14 days) compared to medical management. Although medical management is associated with shorter survival compared to surgical treatment, it is a reasonable alternative when surgery cannot be pursued.


Subject(s)
Cholecystectomy/veterinary , Dog Diseases/surgery , Dog Diseases/therapy , Gallbladder Diseases/veterinary , Mucocele/veterinary , Abdomen/diagnostic imaging , Alkaline Phosphatase/blood , Animals , Bile Duct Diseases/veterinary , Creatinine/blood , Dogs , Female , Gallbladder Diseases/surgery , Gallbladder Diseases/therapy , Male , Mucocele/surgery , Mucocele/therapy , Phosphorus/blood , Prognosis , Retrospective Studies , Survival Analysis , Ultrasonography/veterinary
3.
Eur Ann Otorhinolaryngol Head Neck Dis ; 136(1): 41-42, 2019 Feb.
Article in English | MEDLINE | ID: mdl-30337239

ABSTRACT

INTRODUCTION: Newborns are obligatory nasal breathers. Therefore, nasal obstruction can lead to cyanosis and desaturation. In spite of being very rare, congenital bilateral dacryocystocele is a possible etiology for neonatal respiratory distress. CASE SUMMARY: Case report of a male newborn with respiratory distress caused by a bilateral polypoid and bluish lesion occupying almost the entire inferior nasal meatus. Imaging confirmed bilateral dacryocystocele. Treatment was conservative. There was spontaneous drainage, with relief of respiratory distress. Discussion The diagnosis of congenital dacryocystocele is clinical, although imaging exams may be requested to confirm it. Treatment is controversial, because the natural history is variable. An initial conservative management may be recommended, but, if there is a permanent respiratory obstruction without improvement, surgical management is mandatory.


Subject(s)
Lacrimal Apparatus Diseases/congenital , Mucocele/congenital , Nasal Obstruction/etiology , Nose Diseases/congenital , Respiratory Distress Syndrome, Newborn/etiology , Anti-Bacterial Agents/therapeutic use , Conservative Treatment , Humans , Infant, Newborn , Lacrimal Apparatus Diseases/complications , Lacrimal Apparatus Diseases/therapy , Male , Massage , Mucocele/complications , Mucocele/therapy , Nasal Obstruction/therapy , Nose Diseases/complications , Nose Diseases/therapy , Respiratory Distress Syndrome, Newborn/therapy
4.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 50(10): 624-6, 2015 Oct.
Article in Chinese | MEDLINE | ID: mdl-26757633

ABSTRACT

OBJECTIVE: To evaluate the effect of bleomyin A5 combined with phosphorus-32 colloid in the treatment of mucocele. METHODS: A total of 214 patients divided into three groups, bleomyin A5 (50 cases), phosphorus-32 colloid (50 cases) and bleomyin A5 combined with phosphorus-32 colloid (114 cases). RESULTS: The efficacy of bleomyin A5 group, phosphorus-32 colloid group, and bleomyin A5 combined with phosphorus-32 colloid group was 84% (42/50), 82% (41/50) and 98% (112/114), respectively. There were significant difference in efficacy among the three groups (P < 0.05). The phosphorus-32 colloid group and the bleomyin A5 group had no significant difference in efficacy (P > 0.05). CONCLUSIONS: The independent use of bleomyin A5 and phosphorus-32 colloid is effective, but the combined use of the two methods is more effective.


Subject(s)
Bleomycin/analogs & derivatives , Mucocele/therapy , Phosphorus Radioisotopes/therapeutic use , Bleomycin/therapeutic use , Colloids , Combined Modality Therapy/methods , Humans , Phosphorus , Treatment Outcome
5.
Bol. Asoc. Argent. Odontol. Niños ; 42(1): 12-16, abr.-ago. 2013. ilus
Article in Spanish | LILACS | ID: lil-722385

ABSTRACT

El mucocele (MC) es la lesión más común de la mucosa bucal, como consecuencia de una alteración de las glándulas salivales menores. El tratamiento habitual es quirúrgico y consiste en la resección de la lesión. El objetivo de esta comunicación es presentar una modalidad de intervención multiprofesional no quirúrgica para el tratamiento del MC. Se presenta un estudio de caso que describe el proceso de atención psicológica - fonoaudiológica - odontológica, empleando una pantalla bucal con el propósito de reducir el trauma sobre la lesión del MC, que desaparece sin necesidad de recurrir al tratamiento quirúrgico


Subject(s)
Humans , Male , Adolescent , Dental Care for Children/methods , Child Behavior/psychology , Mucocele/therapy , Patient Care Team , Comprehensive Dental Care , Ferula , Logotherapy/methods
6.
Bol. Asoc. Argent. Odontol. Niños ; 42(1): 12-16, abr.-ago. 2013. ilus
Article in Spanish | BINACIS | ID: bin-130010

ABSTRACT

El mucocele (MC) es la lesión más común de la mucosa bucal, como consecuencia de una alteración de las glándulas salivales menores. El tratamiento habitual es quirúrgico y consiste en la resección de la lesión. El objetivo de esta comunicación es presentar una modalidad de intervención multiprofesional no quirúrgica para el tratamiento del MC. Se presenta un estudio de caso que describe el proceso de atención psicológica - fonoaudiológica - odontológica, empleando una pantalla bucal con el propósito de reducir el trauma sobre la lesión del MC, que desaparece sin necesidad de recurrir al tratamiento quirúrgico(AU)


Subject(s)
Humans , Male , Adolescent , Mucocele/therapy , Patient Care Team , Child Behavior/psychology , Dental Care for Children/methods , Logotherapy/methods , Comprehensive Dental Care , Ferula
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