ABSTRACT
BACKGROUND: Thalamic blood supply consists of four major vascular territories. Out of them paramedian arteries supply ipsilateral paramedian thalami and occasionally rostral mid brain. Rarely both paramedian arteries arise from a common trunk that arise from P1 segment of one sided posterior cerebral artery (PCA). This is usually due to hypoplastic or absent other P1 and this common trunk is termed Artery of Percheron (AOP). Its prevalence is in the range of 7-11% among the general population and AOP infarcts account in an average of 0.4-0.5% of ischemic strokes. Clinical presentation of AOP infarction is characterized by impaired arousal and memory, language impairment and vertical gaze palsy. It also can present with cerebellar signs, hemi paresis and hemi sensory loss. We herein present a case of AOP infarction presenting as transient loss of consciousness and nuclear third nerve palsy. CASE PRESENTATION: A 51 year old previously healthy male, was brought to us, with a Glasgow coma scale (GCS) of 7/15. GCS improved to 11/15 by the next day, however he had a persisting expressive aphasia. Right sided nuclear third nerve palsy was apparent with the improvement of GCS. He did not have pyramidal or cerebellar signs. Thrombolysis was not offered as the therapeutic window was exceeded by the time of diagnosis. Diagnosis was made using magnetic resonance imaging (MRI) that was done after the initial normal non-contrast computer tomography (NCCT) brain. He was enrolled in stroke rehabilitation. Aspirin and atorvastatin was started for the secondary prevention of stroke. He achieved independency of advanced daily living by 1 month, however could not achieve full recovery to be employed as a taxi driver. CONCLUSIONS: Because of the rarity and varied clinical presentation with altered levels of consciousness, AOP infarcts are easily overlooked as a stroke leading to delayed diagnosis. Timely diagnosis can prevent unnecessary investigations and the patient will be benefitted by early revascularization. As it is seldom reported, case reports remain a valuable source of improving awareness among physicians about this clinical entity.
Subject(s)
Cerebral Infarction/diagnosis , Oculomotor Nerve Diseases/diagnosis , Unconsciousness/etiology , Arteries/pathology , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Neuroimaging , Stroke/prevention & control , Thalamus/blood supplyABSTRACT
We describe a patient presenting with vertical one-and-a-half syndrome and concomitant contralesional horizontal gaze paresis as the result of a solitary neurocysticercosis (NCC) lesion in the right midbrain extending into the thalamomesencephalic junction. The patient received an albendazole-dexamethasone course which resulted in resolution of his symptoms. The neuro-ophthalmological complications of NCC are reviewed and the clinical topography of the neuro-ophthalmological findings of this unusual observation are discussed.
Subject(s)
Diplopia/etiology , Neurocysticercosis/complications , Nystagmus, Pathologic/etiology , Ocular Motility Disorders/etiology , Oculomotor Nerve Diseases/etiology , Abducens Nerve Diseases/diagnosis , Adult , Albendazole/therapeutic use , Anthelmintics/therapeutic use , Blepharoptosis/etiology , Dexamethasone/therapeutic use , Diagnosis, Differential , Diplopia/drug therapy , Drug Therapy, Combination , Headache/etiology , Humans , Male , Mesencephalon/parasitology , Mesencephalon/physiopathology , Neurocysticercosis/diagnosis , Neurocysticercosis/drug therapy , Neurocysticercosis/physiopathology , Nystagmus, Pathologic/drug therapy , Ocular Motility Disorders/drug therapy , Oculomotor Nerve Diseases/diagnosis , Oculomotor Nerve Diseases/drug therapy , Oculomotor Nerve Diseases/parasitology , Reflex, Abnormal , Thalamus/parasitology , Thalamus/physiopathologyABSTRACT
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Subject(s)
Humans , Male , Aged , Paresis/diagnosis , Oculomotor Nerve Diseases/diagnosis , Brain Stem/injuries , Anesthesia, Local/adverse effects , Cataract ExtractionABSTRACT
We report the cases of five patients who have experienced postoperative diplopia after cataract surgery under peribulbar anaesthesia and in whom orbital Magnetic Resonance Imaging was performed immediately after the diagnosis. In four patients, the imaging study showed a T2 hyper-intensity signal and swelling of one extraocular muscle that was interpreted as oedema. Therefore, these cases were most probably a result of an accidental i.m. injection of local anaesthetics. In the other patient, the imaging study revealed no abnormality.
Subject(s)
Anesthesia, Local/adverse effects , Diplopia/etiology , Phacoemulsification , Aged , Aged, 80 and over , Female , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Oculomotor Nerve Diseases/diagnosis , Oculomotor Nerve Diseases/etiologyABSTRACT
A 71-year-old woman developed complete third nerve palsy and total blindness of the right eye one month after completing a course of radiotherapy for sphenoid sinus carcinoma over a 13-month period. Differential diagnosis included recurrence of the tumor, radiation-induced second neoplasm, empty sella with chiasmal prolapse and secondary chiasmal arachnoid adhesions, and radionecrosis. Magnetic resonance imaging demonstrated gadolinium contrast enhancement of the right intracranial optic nerve and chiasm, suggesting a radionecrosis process.
Subject(s)
Blindness/etiology , Carcinoma/radiotherapy , Optic Chiasm/radiation effects , Optic Nerve/radiation effects , Paranasal Sinus Neoplasms/radiotherapy , Radiation Injuries/etiology , Sphenoid Sinus/radiation effects , Aged , Carcinoma/etiology , Chemotherapy, Adjuvant , Cisplatin/therapeutic use , Diagnosis, Differential , Female , Fluorouracil/therapeutic use , Humans , Magnetic Resonance Imaging , Neoplasms, Radiation-Induced/etiology , Neoplasms, Second Primary/etiology , Oculomotor Nerve Diseases/diagnosis , Oculomotor Nerve Diseases/etiology , Optic Atrophy/etiology , Optic Chiasm/pathology , Optic Nerve/pathology , Paranasal Sinus Neoplasms/etiology , Visual FieldsABSTRACT
A 43-year-old man with Behçet's disease developed a left oculomotor palsy and a right elevation paresis. His clinical picture was consistent with an isolated fascicular third cranial nerve palsy, considering the mass effect of a large left capsulothalamic lesion extending down into the mesencephalon, which was visualized by CT and (more precisely) by MRI. The patient's clinical status was improved with steroid and immunosuppressive therapy, and radiologic abnormalities resolved markedly in a month.