Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 24
Filter
Add more filters

Complementary Medicines
Country/Region as subject
Publication year range
1.
Acupunct Med ; 42(1): 14-22, 2024 Feb.
Article in English | MEDLINE | ID: mdl-37800350

ABSTRACT

BACKGROUND: Postoperative gastrointestinal dysfunction (PGD) is one of the most common complications among patients who have undergone thoracic surgery. Acupuncture has long been used in traditional Chinese medicine to treat gastrointestinal diseases and has shown benefit as an alternative therapy for the management of digestive ailments. This study aimed to explore the therapeutic effectiveness of acupuncture as a means to aid postoperative recovery of gastrointestinal function in patients undergoing thoracoscopic surgery. METHODS: In total, 112 patients aged 18-70 years undergoing thoracoscopic surgery between 15 June 2022 and 30 August 2022 were randomized into two groups. Patients in the acupuncture group (AG) first received acupuncture treatment 4 h after surgery, and treatment was repeated at 24 and 48 h. Patients in the control group (CG) did not receive any acupuncture treatment. Both groups received the same anesthetic protocol. Ultrasound-guided thoracic paravertebral block (TPVB) was performed in the paravertebral spaces between T4 and T5 with administration of 20 mL of 0.33% ropivacaine. All patients received patient-controlled intravenous analgesia (PCIA) after surgery. RESULTS: Median time to first flatus [interquartile range] in the AG was significantly less than in the CG (23.25 [18.13, 29.75] vs 30.75 [24.13, 45.38] h, p < 0.001). Time to first fluid intake after surgery was significantly less in the AG, as compared with the CG (4 [3, 7] vs 6.5 [4.13, 10.75] h, p = 0.003). Static pain, measured by visual analog scale (VAS) score, was significantly different on the third day after surgery (p = 0.018). Dynamic pain VAS scores were lower in the AG versus CG on the first three postoperative days (p = 0.014, 0.003 and 0.041, respectively). CONCLUSION: Addition of acupuncture appeared to improve recovery of postoperative gastrointestinal function and alleviate posteoperative pain in patients undergoing thoracoscopic surgery. Acupuncture may represent a feasible strategy for the prevention of PGD occurrence. TRIAL REGISTRATION NUMBER: ChiCTR2200060888 (Chinese Clinical Trial Registry).


Subject(s)
Acupuncture Therapy , Gastrointestinal Diseases , Humans , Pain, Postoperative/prevention & control , Pain, Postoperative/drug therapy , Prospective Studies , Ropivacaine/therapeutic use , Thoracoscopy/adverse effects , Thoracoscopy/methods
2.
BMC Cardiovasc Disord ; 23(1): 580, 2023 11 24.
Article in English | MEDLINE | ID: mdl-38001480

ABSTRACT

BACKGROUND: To compare the post-operative pain and quality of life of patients who underwent total thoracoscopic surgery (TTS) or conventional full-sternotomy (CFS) for aortic valve replacement (AVR). METHODS: We reviewed the records of 223 consecutive AVR patients with either TTS or CFS from January 2018 to December 2022. We used a visual analogue scale (VAS) and the Short Form-36 Health Survey (SF-36) to measure the post-operative pain and quality of life, respectively. We also compared the operative data and clinical outcomes between the two groups. RESULTS: The TTS group had lower adjusted mean VAS scores than the CFS group at all time points after surgery (at 1 to 3 days and at 3 and 6 months, p < .001 for all comparisons), indicating less pain. The TTS group also had higher mean SF-36 scores than the CFS group up to 6 months after surgery (p < .001 for all comparisons), indicating better quality of life. The operative time was similar between the two groups (p = .224), but the TTS group had longer cardiopulmonary bypass time and aortic cross-clamp time than the CFS group (p < .001). The TTS group had more pulmonary complications than the CFS group (p = .023). However, there were no significant differences in other major complications or mortality between the two groups. CONCLUSIONS: TTS is a safe and effective alternative to CFS for AVR. TTS resulted in less pain and better quality of life, especially in the early recovery period. However, further prospective randomized controlled studies are needed to confirm our findings.


Subject(s)
Aortic Valve , Heart Valve Prosthesis Implantation , Humans , Aortic Valve/diagnostic imaging , Aortic Valve/surgery , Sternotomy/adverse effects , Quality of Life , Heart Valve Prosthesis Implantation/adverse effects , Postoperative Complications/etiology , Treatment Outcome , Pain, Postoperative/etiology , Pain, Postoperative/complications , Thoracoscopy/adverse effects , Retrospective Studies , Minimally Invasive Surgical Procedures/adverse effects
3.
Chron Respir Dis ; 19: 14799731221133389, 2022.
Article in English | MEDLINE | ID: mdl-36206158

ABSTRACT

OBJECTIVE: We aimed to explore the safety and diagnostic value of medical thoracoscopic lung biopsy in patients with unexplained diffuse interstitial lung disease (ILD) in a single center pilot study. METHOD: We retrospectively analyzed clinical and pathological diagnostic data from 52 patients with diffuse ILD undergoing medical thoracoscopic lung biopsy. RESULTS: Forty-four cases of diffuse ILD were confirmed pathologically, giving a diagnostic rate of 84.6%. Among these 44 patients, 11 patients were diagnosed with cancer, including eight patients with lung adenocarcinoma, three patients with metastases; two from a gastrointestinal malignancy, and one from a granulosa cell tumor of the ovary. There were 17 cases of idiopathic interstitial pneumonia, including nine cases of usual interstitial pneumonia (UIP), four cases of non-specific interstitial pneumonia (NSIP), three cases of cryptogenic organizing pneumonia (COP), and one case of acute interstitial pneumonia (AIP). There were 12 cases of rare interstitial pneumonias, which included six cases of pulmonary alveolar proteinosis, one case each of pulmonary Langerhans cell histiocytosis (LCH) and pulmonary lymphangiomyomatosis, two cases of nodular sarcoidosis, and two cases of chronic eosinophilic pneumonia. We recorded various complications, including bleeding, infection, and pneumothorax. A total of 28 patients (53.8%) experienced at least one of the above complications, but there were no deaths associated with biopsy. CONCLUSIONS: Medical thoracoscopic lung biopsy appears a safe and effective method for diagnosing diffuse ILD of unknown cause but further prospective studies, with larger numbers, including comparison with other established techniques are required.


Subject(s)
Idiopathic Interstitial Pneumonias , Lung Diseases, Interstitial , Anesthesia, Local , Biopsy/methods , Female , Humans , Idiopathic Interstitial Pneumonias/diagnosis , Lung/pathology , Lung Diseases, Interstitial/diagnosis , Pilot Projects , Prospective Studies , Retrospective Studies , Thoracoscopy/adverse effects
4.
Medicine (Baltimore) ; 101(4): e28675, 2022 Jan 28.
Article in English | MEDLINE | ID: mdl-35089213

ABSTRACT

BACKGROUND: Enhanced recovery after surgery suggests the use of multimodal analgesia to optimize the perioperative pain management scheme. At present, studies have shown that the application of acupuncture combined anesthesia in thoracoscopy has achieved good curative effect. However, there is no relevant systematic evaluation. Our study is the first meta-analysis of the effectiveness and safety of acupuncture combined anesthesia in pain management after thoracoscopy, in order to provide strong evidence for clinical support. METHODS: A comprehensive and systematic literature searching will mainly perform on 7 electronic databases (PubMed, the Cochrane Library, Embase, China National Knowledge Infrastructure, Chongqing VIP Information, and WanFang Data, Chinese Biomedical Database) from their inception up to November 30, 2021. We will also search for ongoing or unpublished studies from other websites (eg, PROSPERO, ClinicalTrials.gov, Chinese Clinical Trial Registry) and do manual retrieval for potential gray literature. Only the relevant randomized controlled trials published in English or Chinese were included. Two independent investigators will independently complete literature selection, assessment of risk bias, and data extraction, the disagreements will be discussed with the third party for final decisions. The primary outcome measures: visual analog scale, intraoperative anesthetic dosage, and the consumption of postoperative analgesics. The secondary outcome measures: Pittsburgh Sleep Quality Index, the total sleep time after operation, residence time in the anesthesia recovery room, the duration of hospitalization, and the incidence of adverse reactions and serious events. Assessment of bias risk will follow the Cochrane risk of bias tool. Data processing will be conducted by Stata 15.0 software. RESULTS: We will evaluate the efficacy and safety of acupuncture assisted anesthesia for postoperative pain after thoracoscopy based on randomized controlled trials. CONCLUSION: This study can provide more comprehensive and strong evidence whether acupuncture assisted anesthesia is efficacy and safe for postoperative pain in thoracoscopy. REGISTRATION: The research has been registered and approved on the INPLASY website. The registration number is INPLASY 2021120129.


Subject(s)
Acupuncture Therapy , Anesthesia/adverse effects , Pain, Postoperative/therapy , Thoracoscopy/adverse effects , Acupuncture Therapy/adverse effects , Anesthesia/methods , Humans , Meta-Analysis as Topic , Randomized Controlled Trials as Topic , Research Design , Systematic Reviews as Topic
5.
Reg Anesth Pain Med ; 45(4): 255-259, 2020 04.
Article in English | MEDLINE | ID: mdl-32066592

ABSTRACT

BACKGROUND: Interstitial lung disease (ILD) management guidelines support lung biopsy-guided therapy. However, the high mortality associated with thoracoscopic lung biopsy using general anesthesia (GA) in patients with ILD has deterred physicians from offering this procedure and adopt a diagnostic approach based on high-resolution CT. Here we report that thoracoscopy under regional anesthesia could be a safer alternative for lung biopsy and effectively guide ILD treatment. METHODS: This was a single-center retrospective review of prospectively maintained database and consisted of patients who underwent thoracoscopic lung biopsy between March 2016 and March 2018. Patients were divided into two groups: (A) GA, and (B) regional anesthesia using monitored anesthesia care (MAC) and thoracic epidural anesthesia (TEA). RESULTS: During the study period, 44 patients underwent thoracoscopic lung biopsy. Of these, 15 underwent MAC/TEA. There were no significant differences between the two groups with regard to pulmonary function test and clinicodemographic profile. However, operative time and hospital stay were shorter in MAC/TEA group (32.5±18.5 min vs 50.8±18.4; p=0.004, 1.0±1.3 days vs 10.0±34.7 days; p<0.001, respectively). Eight patients in the GA group, but none in the MAC/TEA group, experienced worsening of ILD after lung biopsy (p=0.03). Additionally, one patient in the GA group died due to acute ILD worsening. No cases of MAC/TEA group had to be converted to GA. In all cases a pathological diagnosis could be made. CONCLUSIONS: Thoracoscopy using regional anesthesia might be a safer alternative to lung biopsy in patients with ILD.


Subject(s)
Anesthesia, Conduction/methods , Anesthesia/methods , Biopsy/adverse effects , Lung Diseases, Interstitial/pathology , Thoracoscopy/adverse effects , Adult , Aged , Aged, 80 and over , Anesthesia/adverse effects , Anesthesia/mortality , Anesthesia, Epidural , Biopsy/methods , Cohort Studies , Female , Humans , Lung/pathology , Male , Middle Aged , Pain, Postoperative , Retrospective Studies , Risk Factors , Thoracoscopy/methods , Treatment Outcome
6.
Pulmonology ; 25(1): 9-14, 2019.
Article in English | MEDLINE | ID: mdl-29898873

ABSTRACT

If the seemingly less invasive semi-flexible pleuroscopes are combined with strategies of conscious sedation and local anesthesia the pleuroscopy has the potential to reach an increasing number of hospital settings. Local experiences can provide valuable information pertaining to the reproducibility of this technique in different scenarios. We performed a retrospective analysis of the clinical records of all patients that had undergone local anesthetic semi-flexible pleuroscopy in our unit between February 2015 and July 2017. Data on demographics, previous biochemical, cytological and histopathological analysis, procedure details, diagnostic and therapeutic results, complications and mortality were collected from all patients. Statistical analysis was performed using SPSS v23. A total of 30 patients were included. They were mainly male (66.7%), with a median age of 72 years (minimum 19 years, maximum 87 years). All presented with exudative pleural effusions and the exam was performed for diagnostic reasons. Pleural tissue was obtained in all patients and the overall diagnostic accuracy was 93.3%. Malignancy was the chief group of diagnosis (66.7%), followed by pleural tuberculosis (13.3%). The procedure was well tolerated and self-limited subcutaneous emphysema was the only complication registered (13.3%). No deaths were associated with the procedure. Our results globally overlap those of wider series and reinforce the perception that local anesthetic semi-flexible pleuroscopy is a well-tolerated, safe and highly accurate diagnostic and therapeutic tool which has proved to be both feasible and effective in our experience.


Subject(s)
Anesthesia, Local/adverse effects , Anesthetics, Local/adverse effects , Pleural Effusion/diagnostic imaging , Thoracoscopy/instrumentation , Adjuvants, Anesthesia/administration & dosage , Adult , Aged , Aged, 80 and over , Anesthetics, Local/administration & dosage , Female , Humans , Male , Midazolam/administration & dosage , Middle Aged , Pleura/pathology , Pleural Effusion/etiology , Pleural Effusion/metabolism , Pleural Effusion/pathology , Reproducibility of Results , Retrospective Studies , Subcutaneous Emphysema/etiology , Thoracoscopes/trends , Thoracoscopy/adverse effects , Thoracoscopy/methods
7.
J Cardiovasc Electrophysiol ; 28(4): 466-473, 2017 Apr.
Article in English | MEDLINE | ID: mdl-28063271

ABSTRACT

INTRODUCTION: Despite the overall safety, transvenous lead extraction (TLE) remains a challenging procedure with inherent risks, where surgery can still be required in elective cases. In this study, we report our experience with a minimally invasive "hybrid" approach, defined as a procedure performed by an electrophysiologist with the support of a cardiac surgeon in the same operative session. METHODS AND RESULTS: We reported 12 cases of planned hybrid lead extraction; minithoracotomy and thoracoscopy were performed on 10 (83%) and 2 (17%) patients, respectively. A total of 25 leads out of 27 (median lead age 19 years) were successfully extracted with laser, mechanical or combined transvenous sheath. In 3 patients, the direct monitoring of vascular and myocardial integrity allowed for prompt treatment of potential vascular injury during the lead extraction maneuvers. Mean in-hospital stay was 4 ± 2 days. There were no major intraoperative complications and no deaths occurred after 30 days' follow-up. CONCLUSION: The hybrid approach, with minithoracotomy or thoracoscopy, is feasible and it might increase the safety in the most challenging TLE procedures: the minimally invasive surgical intervention allows for continuous monitoring of the critical cardiac structures and prompt treatment of potential complications.


Subject(s)
Cardiac Resynchronization Therapy Devices , Defibrillators, Implantable , Device Removal/methods , Pacemaker, Artificial , Thoracoscopy , Thoracotomy , Adult , Aged , Aged, 80 and over , Cardiologists , Device Removal/adverse effects , Electrophysiologic Techniques, Cardiac , Feasibility Studies , Female , Humans , Length of Stay , Male , Patient Care Team , Prosthesis Design , Prosthesis Failure , Risk Factors , Surgeons , Thoracoscopy/adverse effects , Thoracotomy/adverse effects , Time Factors , Treatment Outcome
8.
J Pediatr Surg ; 51(2): 304-9, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26592954

ABSTRACT

AIM OF THE STUDY: The management of newborns with esophageal atresia (EA) and right aortic arch (RAA) is still an unsolved problem. This study provides a systematic review of epidemiology, diagnosis, management and short-term results of children with EA and RAA. MATERIALS AND METHODS: The PubMed database was searched for original studies on children with EA and RAA. In each study, data were extracted for the following outcomes: number of patients, associated anomalies, type of surgical repair, morbidity and mortality rate. RESULTS: Eight studies were selected, including 54 patients with EA and RAA. RAA was encountered in 3.6% of infants. Preoperative detection of RAA was reported in 7 of them. In these patients, primary anastomosis was achieved through the right approach in 3 (thoracotomy in 2 and thoracoscopy in 1) while the left approach was the primary choice in 4 (thoracotomy in 2 and thoracoscopy in 2). No significant differences were found between the right and left approaches with regard to leaks (P=0.89), strictures (P=1) or mortality (P=1). In 47/54 patients (87%) RAA was noted during right thoracotomy, and primary anastomosis was achieved through the same approach in 29 (61.7%); conversion to other approaches (left thoracotomy or esophageal substitution) was performed in 15 children (38.3%). No significant differences were found between primary left thoracotomy (LT) and LT after RT with regard to leaks (P=0.89), strictures (P=1) or mortality (P=1). CONCLUSIONS: Skills and preferences of the surgeon still guide the choice of surgical approach even when preoperatively faced with RAA. A multicenter, prospective randomized study is strongly required.


Subject(s)
Aorta, Thoracic/abnormalities , Aorta, Thoracic/surgery , Esophageal Atresia/surgery , Anastomotic Leak/etiology , Constriction, Pathologic/etiology , Esophageal Atresia/diagnosis , Esophageal Atresia/epidemiology , Humans , Infant, Newborn , Thoracoscopy/adverse effects , Thoracotomy/adverse effects
9.
World J Surg ; 39(9): 2269-73, 2015 Sep.
Article in English | MEDLINE | ID: mdl-26088611

ABSTRACT

OBJECTIVES: Thoracic sympathectomy is considered the most effective method to treat palmar hyperhidrosis. We presented a novel procedure for thoracic sympathectomy treating palmar hyperhidrosis which could be performed under monitored anesthesia care. The aim of this study was to evaluate the continuing efficacy and safety of this innovative surgery. METHOD: From May 2011 to May 2014, we performed the single-port endoscopic thoracic sympathectomy (ETS) with a flexible thoracoscopy in 32 patients under monitored anesthesia care. All patients were followed up until today. RESULTS: Under monitored anesthesia, all patients were awake during the procedure. A proper sedation and local anesthesia make it possible for patients to communicate with surgeons. The symptoms disappeared immediately when the sympathectomy was done. No surgical complications occurred during the procedure. All patients were discharged from the hospital on the first morning of postoperative day. Compared with the traditional approach, the advantages of less operative costs, fewer hospital days, and better recovery were suggested. CONCLUSIONS: Single-port ETS with flexible thoracoscopy under monitored anesthesia is a promising procedure for palmar hyperhidrosis.


Subject(s)
Anesthesia, Local , Conscious Sedation , Hand Dermatoses/surgery , Hyperhidrosis/surgery , Sympathectomy/methods , Thoracoscopy/methods , Adolescent , Adult , Female , Humans , Length of Stay , Male , Monitoring, Intraoperative , Prospective Studies , Sympathectomy/adverse effects , Thoracoscopy/adverse effects , Treatment Outcome , Young Adult
10.
Thorax ; 70(2): 189-91, 2015 Feb.
Article in English | MEDLINE | ID: mdl-24658342

ABSTRACT

The BTS pleural procedures audit collected data over a 2-month period in June and July 2011. In contrast with the 2010 audit, which focussed simply on chest drain insertions, data on all pleural aspirations and local anaesthetic thoracoscopy (LAT) was also collected. Ninety hospitals submitted data, covering a patient population of 33 million. Twenty-one per cent of centres ran a specialist pleural disease clinic, 71% had a nominated chest drain safety lead, and 20% had thoracic surgery on site. Additionally, one-third of centres had a physician-led LAT service.


Subject(s)
Chest Tubes/standards , Medical Audit , Paracentesis/standards , Patient Safety , Thoracoscopy/standards , Anesthesia, Local , Chest Tubes/adverse effects , Chest Tubes/statistics & numerical data , Hospitals/standards , Hospitals/statistics & numerical data , Humans , Informed Consent/statistics & numerical data , Paracentesis/adverse effects , Paracentesis/statistics & numerical data , Pleural Cavity , Pleural Effusion/surgery , Pneumothorax/surgery , Societies, Medical , Thoracoscopy/adverse effects , Thoracoscopy/statistics & numerical data , Ultrasonography, Interventional/standards , Ultrasonography, Interventional/statistics & numerical data , United Kingdom
11.
Chest ; 146(2): e34-e37, 2014 Aug.
Article in English | MEDLINE | ID: mdl-25091759

ABSTRACT

Local anesthetic (medical) thoracoscopy is used with increasing frequency by pulmonologists worldwide for both diagnostic and therapeutic purposes, notably in comorbid patients who may not be physiologically robust enough for general anesthesia. Understanding the complications that can arise and how to manage them is crucial for any physician performing this procedure. Reexpansion pulmonary edema is a rare but recognized complication of draining pleural effusions and pneumothoraces that has not been described previously in association with physician-led thoracoscopy. This case provides an opportunity for an overview of what is known about this unusual but potentially fatal condition. Data correlating ultrasonographic, radiographic, and clinical progression are also presented to highlight the potential usefulness of ultrasonography in identifying lung parenchymal abnormalities such as extravascular lung water.


Subject(s)
Anesthesia, Local/adverse effects , Anesthetics, Local/administration & dosage , Lung/diagnostic imaging , Pleural Effusion/surgery , Pulmonary Edema/diagnosis , Radiography, Thoracic/methods , Thoracoscopy/adverse effects , Anesthesia, Local/methods , Diagnosis, Differential , Drainage/methods , Follow-Up Studies , Humans , Male , Middle Aged , Pulmonary Edema/etiology , Recurrence , Ultrasonography
12.
Int J Cardiol ; 173(2): 229-35, 2014 May 01.
Article in English | MEDLINE | ID: mdl-24630384

ABSTRACT

INTRODUCTION: Patients with atrial fibrillation (AF) with enlarged atria or previous pulmonary vein isolation (PVI) are challenging patients for catheter ablation. Thoracoscopic surgery is an effective treatment for these patients but comes at the cost of an increase in adverse events. Recently, electrophysiological (EP) guided approaches to thoracoscopic surgery have been described which consist of EP guidance by measurement of conduction block across ablation lines. In this study we describe the efficacy and safety of EP-guided thoracoscopic surgery for AF in patients with enlarged atria and/or prior failed catheter ablation. METHODS & RESULTS: A total of 72 patients were included. Two different approaches to EP-guided thoracoscopic surgery were implemented: epicardial or endocardial EP-guidance at the time of surgery. Residual intraoperative conduction requiring additional ablation was detected with epicardial or endocardial mapping techniques in 50% and 11%, respectively. Additional epicardial or endocardial ablation was performed until bidirectional block was confirmed. Follow-up consisted of an ECG and a 24h Holter at 3, 6 and 12 months after the procedure. A total of 57 patients (79%) had freedom of AF and were off anti-arrhythmic drugs at one year follow-up (30 paroxysmal (83%), 27 persistent AF (75%)). Adverse events occurred in 13 patients (6 major). None of our patients died and all events were reversible. CONCLUSION: EP-guidance of thoracoscopic surgery can be safely performed both epicardially and endocardially and is associated with a high rate of long-term maintenance of sinus rhythm in patients with enlarged atria and/or a previously failed ablation.


Subject(s)
Atrial Fibrillation/physiopathology , Atrial Fibrillation/surgery , Catheter Ablation/methods , Electrophysiologic Techniques, Cardiac , Thoracoscopy/methods , Adult , Aged , Atrial Fibrillation/diagnosis , Catheter Ablation/adverse effects , Electrocardiography, Ambulatory , Endocardium/physiopathology , Female , Follow-Up Studies , Heart Block/diagnosis , Heart Block/physiopathology , Heart Block/surgery , Humans , Male , Middle Aged , Pericardium/physiopathology , Postoperative Complications/prevention & control , Prospective Studies , Thoracoscopy/adverse effects , Treatment Outcome
13.
Vestn Khir Im I I Grek ; 173(5): 23-6, 2014.
Article in Russian | MEDLINE | ID: mdl-25823330

ABSTRACT

The standard transvenous electrocardiostimulation (ECS) is currently used in many specialized hospitals. The authors offered and launched systematic application of simple but available technique of epymiocardiac ECS using pericardoscopy since middle of 80th. According to this principle, the authors developed some diversities of manipulation which are distinctive due to their availability, reliability and supersafety. The method could be recommended for wide-spread usage in practice because of high efficacy, few complications and absence of fatal outcomes in correct intervention. Described methods used in treatment of considerable quantity of patients and adapted to real work conditions of public health hospitals.


Subject(s)
Arrhythmias, Cardiac/therapy , Electrophysiologic Techniques, Cardiac , Postoperative Complications , Thoracoscopy , Arrhythmias, Cardiac/diagnosis , Comparative Effectiveness Research , Electrophysiologic Techniques, Cardiac/adverse effects , Electrophysiologic Techniques, Cardiac/instrumentation , Electrophysiologic Techniques, Cardiac/methods , Humans , Postoperative Complications/etiology , Postoperative Complications/prevention & control , Reproducibility of Results , Thoracoscopy/adverse effects , Thoracoscopy/methods
14.
Trials ; 13: 230, 2012 Nov 30.
Article in English | MEDLINE | ID: mdl-23199187

ABSTRACT

BACKGROUND: For esophageal cancer patients, radical esophagolymphadenectomy is the cornerstone of multimodality treatment with curative intent. Transthoracic esophagectomy is the preferred surgical approach worldwide allowing for en-bloc resection of the tumor with the surrounding lymph nodes. However, the percentage of cardiopulmonary complications associated with the transthoracic approach is high (50 to 70%).Recent studies have shown that robot-assisted minimally invasive thoraco-laparoscopic esophagectomy (RATE) is at least equivalent to the open transthoracic approach for esophageal cancer in terms of short-term oncological outcomes. RATE was accompanied with reduced blood loss, shorter ICU stay and improved lymph node retrieval compared with open esophagectomy, and the pulmonary complication rate, hospital stay and perioperative mortality were comparable. The objective is to evaluate the efficacy, risks, quality of life and cost-effectiveness of RATE as an alternative to open transthoracic esophagectomy for treatment of esophageal cancer. METHODS/DESIGN: This is an investigator-initiated and investigator-driven monocenter randomized controlled parallel-group, superiority trial. All adult patients (age ≥ 18 and ≤ 80 years) with histologically proven, surgically resectable (cT1-4a, N0-3, M0) esophageal carcinoma of the intrathoracic esophagus and with European Clinical Oncology Group performance status 0, 1 or 2 will be assessed for eligibility and included after obtaining informed consent. Patients (n = 112) with resectable esophageal cancer are randomized in the outpatient department to either RATE (n = 56) or open three-stage transthoracic esophageal resection (n = 56). The primary outcome of this study is the percentage of overall complications (grade 2 and higher) as stated by the modified Clavien-Dindo classification of surgical complications. DISCUSSION: This is the first randomized controlled trial designed to compare RATE with open transthoracic esophagectomy as surgical treatment for resectable esophageal cancer. If our hypothesis is proven correct, RATE will result in a lower percentage of postoperative complications, lower blood loss, and shorter hospital stay, but with at least similar oncologic outcomes and better postoperative quality of life compared with open transthoracic esophagectomy. The study started in January 2012. Follow-up will be 5 years. Short-term results will be analyzed and published after discharge of the last randomized patient. TRIAL REGISTRATION: Dutch trial register: NTR3291 ClinicalTrial.gov: NCT01544790.


Subject(s)
Adenocarcinoma/surgery , Carcinoma, Squamous Cell/surgery , Esophageal Neoplasms/surgery , Esophagectomy/methods , Laparoscopy , Research Design , Robotics , Surgery, Computer-Assisted , Thoracoscopy , Adenocarcinoma/economics , Adenocarcinoma/mortality , Adenocarcinoma/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Carcinoma, Squamous Cell/economics , Carcinoma, Squamous Cell/mortality , Carcinoma, Squamous Cell/pathology , Clinical Protocols , Cost-Benefit Analysis , Esophageal Neoplasms/economics , Esophageal Neoplasms/mortality , Esophageal Neoplasms/pathology , Esophagectomy/adverse effects , Esophagectomy/economics , Esophagectomy/mortality , Hospital Costs , Hospital Mortality , Humans , Laparoscopy/adverse effects , Laparoscopy/economics , Laparoscopy/mortality , Length of Stay , Lymph Node Excision , Middle Aged , Neoplasm Staging , Netherlands , Postoperative Complications/mortality , Quality of Life , Risk Factors , Surgery, Computer-Assisted/adverse effects , Surgery, Computer-Assisted/economics , Surgery, Computer-Assisted/mortality , Thoracoscopy/adverse effects , Thoracoscopy/economics , Thoracoscopy/mortality , Time Factors , Treatment Outcome , Young Adult
15.
J Thorac Cardiovasc Surg ; 144(3): S52-7, 2012 Sep.
Article in English | MEDLINE | ID: mdl-22743175

ABSTRACT

OBJECTIVE: The aim of this report is to describe technical maneuvers used to complete minimally invasive resections of the chest wall successfully. METHODS: Case videos of advanced thoracoscopic chest wall resections performed at a comprehensive cancer center were reviewed, as were published reports. These were analyzed for similarities and also categorized to summarize alternative approaches. RESULTS: Limited chest wall resections en bloc with lobectomy can be accomplished with port placement similar to that used for typical thoracoscopic anatomic resections, particularly when the utility incision is close to the region of excision. Generally, chest wall resection precedes lobectomy. Ribs can be transected with Gigli saws, endoscopic shears, or high-speed drills. Division of bone and overlying soft tissue can be planned precisely using thoracoscopic guidance. Isolated primary chest wall masses may require different port position and selective reconstruction using synthetic materials. Patch anchoring can be accomplished by devices that facilitate laparoscopic port site fascial closure. CONCLUSIONS: Thoracoscopic chest wall resections have been accomplished safely using tools and maneuvers summarized here. Further outcomes research is necessary to identify the benefits of thoracoscopic chest wall resection over an open approach.


Subject(s)
Plastic Surgery Procedures/methods , Pneumonectomy/methods , Thoracic Wall/surgery , Thoracoscopy , Humans , Osteotomy , Pneumonectomy/adverse effects , Plastic Surgery Procedures/adverse effects , Ribs/surgery , Thoracoscopy/adverse effects , Treatment Outcome , Video Recording
16.
Interact Cardiovasc Thorac Surg ; 12(5): 667-70, 2011 May.
Article in English | MEDLINE | ID: mdl-21297136

ABSTRACT

For pleurodesis, talc administered by poudrage is usually insufflated blindly from a single port of entry using the standard method with a small-diameter rigid thoracoscope. In order to visually perform talc poudrage from a single port, we introduced a catheter technique through a flexi-rigid thoracoscope. Patients with uncontrolled and symptomatic pleural effusion requiring pleurodesis underwent flexi-rigid thoracoscopy under local anesthesia for talc poudrage. A dedicated catheter with 2.1-mm inner diameter was connected to a talc atomizer and inserted through the working channel of the flexi-rigid thoracoscope to insufflate talc into the pleural cavity under visualization. Nine patients were included in this study. Three patients were >75 years old, and two were Karnofsky performance status 50. Three patients received propofol for sedation and six were not sedated. Mean operative time was 30.8 min for all patients, and 21.3 min for cases without sedation. All procedures were performed easily under clear visualization with no major complications or catheter obstructions. This novel approach for talc pleurodesis using a catheter was well-tolerated and seems feasible for patients with uncontrolled pleural effusion. We consider this technique useful even for difficult cases, such as elderly patients or those with relatively low performance status.


Subject(s)
Anesthesia, Local , Catheters , Pleural Effusion/therapy , Pleurodesis/instrumentation , Pleurodesis/methods , Talc/administration & dosage , Thoracoscopes , Thoracoscopy/instrumentation , Aged , Aged, 80 and over , Anesthetics, Intravenous/administration & dosage , Equipment Design , Female , Humans , Insufflation , Japan , Karnofsky Performance Status , Male , Middle Aged , Pleurodesis/adverse effects , Propofol/administration & dosage , Prospective Studies , Thoracoscopy/adverse effects , Time Factors , Treatment Outcome
18.
Vnitr Lek ; 52(4): 321-7, 2006 Apr.
Article in Czech | MEDLINE | ID: mdl-16755988

ABSTRACT

Videothoracoscopy (VTS) has been performed in the Department of Pneumology in Plzen since the year 2001. Up to-September 2005 there were realized 75 videothoracoscopies, all under local anaesthesia with analgosedation and during the spontaneous ventilation. The objective of the present work is to demonstrate that the so called "medical" videothoracoscopy is very well tolerated, quick and accurate miniinvasive method of examination of pleural pathological states, which has a high diagnostic effect and minimal complications. During the exploration it is possible to carry out, besides the collection of bioptic samples from parietal as well as visceral pleura, a whole range of therapeutical acts - evacuation of effusion, mechanical disruption of adhesions in case of empyema with its subsequent drainage or pleurodesis with talc in case of malignant exudates. As for the basic indication of the medica VTS, we consider it to be the differential diagnosis of a pleural effusion of unclear etiology, consisting mostly in the confirmation or exclusion of malignant exudates. The differential diagnosis with the help of VTS between the nonmalignant (mostly inflammatory) and malignant exudate was successful, in our group of patients, in 96 %. The operation was well tolerated by all patients and in none of them occurred significant complications or consequences.


Subject(s)
Anesthesia, Local , Pleural Effusion/diagnosis , Thoracoscopy , Video Recording , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Pleural Effusion/therapy , Pleural Effusion, Malignant/diagnosis , Pleural Effusion, Malignant/therapy , Thoracoscopy/adverse effects
19.
J Laparoendosc Adv Surg Tech A ; 16(6): 639-42, 2006 Dec.
Article in English | MEDLINE | ID: mdl-17243888

ABSTRACT

PURPOSE: To assess whether perioperative hypnosis can reduce the length of hospitalization and alter the need for postoperative analgesics in patients undergoing the Nuss procedure. MATERIALS AND METHODS: Ten consecutive patients (age range, 12-18 years) underwent the Nuss procedure with the same operative technique. For pain management they were divided into two sequential groups: the 5 patients in the nonhypnosis group were managed with an epidural catheter, and analgesia was supplemented with intravenous or oral narcotics as requested. These patients all required Foley catheters for bladder drainage while the epidural was in place. The second group of 5 patients was prepared by teaching them self-hypnosis for postoperative pain management in one or two brief sessions. Postoperative self-hypnosis was prescribed and encouraged. These patients were allowed patient controlled analgesia and were supplemented with intravenous or oral narcotics as requested. Four of the patients in this group required a straight catheterization of the bladder the evening of surgery. Data collected included hospitalization and analgesia requirements as well as other unusual findings. RESULTS: The patients in the hypnosis group spend an average of 2.8 days in the hospital compared with 4.6 days in the nonhypnosis group (p < 0.01). There was also a trend toward less parenteral narcotic use. Postoperative discomfort was better controlled with oral analgesics in the hypnosis group. There were no adverse effects from the hypnosis. CONCLUSION: In this small study, perioperative hypnosis was associated with a reduced hospital stay in patients undergoing the Nuss procedure for pectus excavatum.


Subject(s)
Funnel Chest/surgery , Hypnosis, Anesthetic , Length of Stay , Pain, Postoperative/prevention & control , Thoracoscopy/adverse effects , Adolescent , Child , Humans , Male , Narcotics/administration & dosage , Pain, Postoperative/etiology , Treatment Outcome
20.
Int Surg ; 82(3): 232-9, 1997.
Article in English | MEDLINE | ID: mdl-9372365

ABSTRACT

In many instances surgical intervention in the chest has been replaced by the minimally invasive thoracoscopic or VATS approach. With such a technique there are disadvantages, complications and contraindications that develop or exist. Disadvantages include the loss of tactile sensation and the cost of the procedural equipment. Absolute contraindications include a fused lung, markedly unstable patient, shock or cardiac arrest, and an individual unable to tolerate partial or complete unilateral collapse of the lung. Lesser contraindications include the patient with bleeding tendencies or under anticoagulant therapy. The few major complications we have seen include prolonged air leak, pulmonary atelectasis and respiratory failure, the "down" lung syndrome or retained secretions. Technical complications including inability to locate the lesion because of its small size, penetration of the lung or inadequate resection of a tumor with subsequent seeding of the tract through the pleural and chest wall have been reported. Major bleeding has not occurred in our institution. Mortality has been seen only in the preterminal malignancy patient.


Subject(s)
Thoracoscopy/adverse effects , Anesthesia, Local/adverse effects , Anesthesia, Local/methods , Contraindications , Heart Diseases/etiology , Humans , Lung Diseases/etiology
SELECTION OF CITATIONS
SEARCH DETAIL