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1.
Acta Neurochir (Wien) ; 159(11): 2123-2125, 2017 11.
Artículo en Inglés | MEDLINE | ID: mdl-28681273

RESUMEN

In 1995 a 16-year old girl was diagnosed with a large left thalamic AVM that was considered unsuitable for microsurgical resection and was treated with radiotherapy twice, which led to angiographic cure. She re-presented 19 years after initial treatment with a symptomatic acute thalamic haemorrhage. Her digital subtraction angiography was negative for arterio-venous shunting. MRI/MRA showed cystic change with adjacent contrast enhancement in the region of the previously irradiated arteriovenous malformation. The patient underwent an interhemispheric transcallosal resection of the left thalamic haemorrhagic lesion via a contralateral craniotomy. Intra-operatively there was a cystic cavity filled with blood products in association with thrombosed, calcified vessels as well as actively filling vessels. Histologically there were aggregated abnormal blood vessels with a dilated lumen and surrounded by brain parenchyma. Some of the vessel walls were thickened with fibrosis and some were arterialised with presence of elastin fibres. Potential mechanisms for the delayed haemorrhage are discussed.


Asunto(s)
Hemorragia Cerebral/cirugía , Malformaciones Arteriovenosas Intracraneales/radioterapia , Tálamo/irrigación sanguínea , Adolescente , Adulto , Angiografía de Substracción Digital , Angiografía Cerebral , Hemorragia Cerebral/etiología , Progresión de la Enfermedad , Femenino , Humanos , Malformaciones Arteriovenosas Intracraneales/complicaciones , Malformaciones Arteriovenosas Intracraneales/diagnóstico por imagen , Angiografía por Resonancia Magnética , Imagen por Resonancia Magnética , Procedimientos Neuroquirúrgicos , Radiocirugia , Tálamo/cirugía , Factores de Tiempo
2.
ANZ J Surg ; 76(3): 163-74, 2006 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-16626360

RESUMEN

BACKGROUND: Traumatic brain injury is a major cause of mortality and morbidity, particularly among young men. The efficacy and safety of most of the interventions used in the management of patients with traumatic brain injury remain unproven. Examples include the 'cerebral perfusion pressure-targeted' and 'volume-targeted' management strategies for optimizing cerebrovascular haemodynamics and specific interventions, such as hyperventilation, osmotherapy, cerebrospinal fluid drainage, barbiturates, decompressive craniectomy, therapeutic hypothermia, normobaric hyperoxia and hyperbaric oxygen therapy. METHODS: A review of the literature was performed to examine the evidence base behind each intervention. RESULTS: There is no class I evidence to support the routine use of any of the therapies examined. CONCLUSION: Well-designed, large, randomized controlled trials are needed to determine therapies that are safe and effective from those that are ineffective or harmful.


Asunto(s)
Lesiones Encefálicas/terapia , Manitol/uso terapéutico , Barbitúricos/farmacología , Barbitúricos/uso terapéutico , Lesiones Encefálicas/fisiopatología , Lesiones Encefálicas/cirugía , Descompresión Quirúrgica , Diuréticos Osmóticos/uso terapéutico , Drenaje , Hemodinámica , Humanos , Oxigenoterapia Hiperbárica , Hipotermia , Presión Intracraneal/efectos de los fármacos , Solución Salina Hipertónica/uso terapéutico , Cráneo/cirugía
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